A simple synthetic route to methyl 3-fluoropyridine-4-carboxylate by nucleophilic aromatic substitution

Tjosås, Freddy; Fiksdahl, Anne
Journal article, Peer reviewed
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URI
http://hdl.handle.net/11250/2359626
Date
2006
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Original version
Molecules 2006, 11:130-133   10.3390/11020130
Abstract
The nitro group of methyl 3-nitropyridine-4-carboxylate (1) has successfully

been replaced by fluoride anion via nucleophilic aromatic substitution to give the 3-fluoropyridine-

4-carboxylate 2.
Publisher
MDPI
Journal
Molecules