dc.contributor.author | Michalsen, Vilde Lehne | |
dc.contributor.author | Vandvik, Per Olav | |
dc.contributor.author | Farup, Per Grønaas | |
dc.date.accessioned | 2015-09-29T12:41:17Z | |
dc.date.accessioned | 2015-10-16T10:59:13Z | |
dc.date.available | 2015-09-29T12:41:17Z | |
dc.date.available | 2015-10-16T10:59:13Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Health and Quality of Life Outcomes 2015, 13(1) | nb_NO |
dc.identifier.issn | 1477-7525 | |
dc.identifier.uri | http://hdl.handle.net/11250/2356334 | |
dc.description.abstract | Background: Reduced quality of life (QoL) is often the main problem for patients with irritable bowel syndrome
(IBS). This study aimed at finding predictors of reduced physical and mental quality of life (QoL) accessible for
intervention.
Methods: Consecutive patients with IBS (according to the Rome II criteria) visiting a general practitioner were
included in a prospective cohort study and followed up for 6−9 months. At the last visit, information about
sociodemographic characteristics, abdominal complaints, QoL and a range of physical and mental comorbidities
were collected. Physical and mental QoL were measured with the generic QoL instrument Short Form-12 Physical
Component Score (SF-12 PCS) and Short Form-12 Mental Component Score (SF-12 MCS) respectively. The normal
scores are 50. This cross-sectional study used data from the last visit.
Results: Out of 208 patients included in the cohort study, 149 (female/male: 105/44) with a mean age of 52 years
(SD 15.3) were available for the analyses. Physical and mental QoL were reduced, the mean SF-12 PCS and SF-12
MCS scores were 38.4 (SD 11.9) and 45.0 (SD 11.3) respectively. The main independent predictors of low SF-12 PCS
and SF-12 MCS were subjective health complaints and organic diseases, and affective disorders respectively. The
severity of IBS symptoms was of minor clinical importance.
Conclusions: To help patients with IBS and reduced QoL, treatment should focus on QoL and not on relief of IBS
symptoms. The different causes of reduced physical and mental QoL make an individually directed treatment
necessary. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | BioMed Central | nb_NO |
dc.title | Predictors of health-related quality of life in patients with irritable bowel syndrome. A cross-sectional study in Norway | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | en_GB |
dc.date.updated | 2015-09-29T12:41:17Z | |
dc.source.volume | 13 | nb_NO |
dc.source.journal | Health and Quality of Life Outcomes | nb_NO |
dc.source.issue | 1 | nb_NO |
dc.identifier.doi | 10.1186/s12955-015-0311-8 | |
dc.identifier.cristin | 1265048 | |
dc.description.localcode | © 2015 Michalsen et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | nb_NO |