Now showing items 1-20 of 729

    • 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...
    • 18F-Fluciclovine PET/MRI for preoperative lymph node staging in high-risk prostate cancer patients 

      Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Willoch, Frode; Størkersen, Øystein; Sandsmark, Elise; Moestue, Siver Andreas; Tessem, May-Britt; Halvorsen, Dag; Kjøbli, Eirik; Angelsen, Anders; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)
      Objective To investigate the diagnostic potential of simultaneous 18F-fluciclovine PET/MRI for pelvic lymph node (LN) staging in patients with high-risk prostate cancer. Methods High-risk prostate cancer patients (n=28) ...
    • 2-hydroxyglutarate as a magnetic resonance biomarker for glioma subtyping 

      Esmaeili, Morteza; Vettukattil, Riyas M; Bathen, Tone Frost (Journal article; Peer reviewed, 2013)
      Mutations in the isocitrate dehydrogenase (IDH) genes are frequently found in gliomas and in a fraction of acute myeloid leukemia patients. This results in the production of an oncometabolite, 2-hydroxyglutarate (2-HG). ...
    • 3D ultrasound reconstruction algorithms from analog and digital data 

      Solberg, Ole Vegard; Lindseth, Frank; Bø, Lars Eirik; Muller, Sebastien; Meland, Janne Beate Lervik; Tangen, Geir Arne; Hernes, Toril A. Nagelhus (Journal article; Peer reviewed, 2010)
      Freehand 3D ultrasound is increasingly being introduced in the clinic for diagnostics and image-assisted interventions. Various algorithms exist for combining 2D images of regular ultrasound probes to 3D volumes, being ...
    • A 95 year-old suffering circulatory arrest after accidental hypothermia: A case report 

      Carlsen, Anders Wetting; Winnerkvist, Anders; Greiff, Guri (Journal article; Peer reviewed, 2017)
      Background The elderly are vulnerable to cold and prone to accidental hypothermia, both because of environmental and endogenous factors. The incidence of severe accidental hypothermia among the elderly is poorly described, ...
    • A balanced tissue composition reveals new metabolic and gene expression markers in prostate cancer 

      Tessem, May-Britt; Bertilsson, Helena; Angelsen, Anders; Bathen, Tone Frost; Drabløs, Finn Sverre; Rye, Morten Beck (Journal article; Peer reviewed, 2016)
      Molecular analysis of patient tissue samples is essential to characterize the in vivo variability in human cancers which are not accessible in cell-lines or animal models. This applies particularly to studies of tumor ...
    • A complete national cohort study of prescriptions of analgesics and benzodiazepines to cancer survivors in Norway 10 years after diagnosis 

      Fredheim, Olav Magnus; Skurtveit, Svetlana; Handal, Marte; Hjellvik, Vidar (Journal article; Peer reviewed, 2019)
      Chronic pain due to surgery, radiotherapy, or chemotherapy is prevalent in long-term cancer survivors. Chronic pain due to successful cancer treatment should be treated as chronic nonmalignant pain, primarily with ...
    • A computational pipeline for quantification of mouse myocardial stiffness parameters 

      Nordbø, Øyvind; Lamata, P.; Land, Sander; Niederer, Steven A.; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Martens, Harald; Gjuvsland, Arne Bjørke; Tøndel, Kristin; Torp, Hans; Lohezic, M; Schneider, Jürgen; Remme, Espen W.; Smith, Nicolas P; Omholt, Stig W; Vik, Jon Olav (Journal article; Peer reviewed, 2014)
      The mouse is an important model for theoretical–experimental cardiac research, and biophysically based whole organ models of the mouse heart are now within reach. However, the passive material properties of mouse myocardium ...
    • A consensus-based template for documenting and reporting in physician-staffed pre-hospital services 

      Krüger, Andreas J.; Lockey, David; Kurola, Juoni; Di Bartolomeo, Stefano; Castrén, Maaret; Mikkelsen, Søren; Lossius, Hans Morten (Journal article; Peer reviewed, 2011)
      Background: Physician-staffed pre-hospital units are employed in many Western emergency medical services (EMS) systems. Although these services usually integrate well within their EMS, little is known about the quality ...
    • A fast 4D B-spline framework for model-based reconstruction and regularization in vector flow imaging 

      Grønli, Thomas; Wigen, Morten Smedsrud; Segers, Patrick; Løvstakken, Lasse (Journal article; Peer reviewed, 2018)
      A generic framework for model-based regularization and reconstruction is described, with applications in a wide range of noisy measurement scenarios. The framework employs automatic differentiation and stochastic gradient ...
    • A flying start? Early interval training in heart failure rehabilitation 

      Ellingsen, Øyvind (Journal article; Peer reviewed, 2017)
    • A multi-center comparison of vO2peak trainability between interval training and moderate intensity continuous training 

      Williams, Camilla J.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Voisin, Sarah; Li, Zhixiu; Harvey, Nicholas; Croci, Ilaria; Taylor, Jenna L; Gajanand, Trishan; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Pattyn, Nele; Howden, Erin J.; Keating, Shelley E.; Bye, Anja; Stensvold, Dorthe; Wisløff, Ulrik; Papadimitriou, Ioannis; Yan, Xu; Bishop, David J.; Eynon, Nir; Coombes, Jeff S. (Journal article; Peer reviewed, 2019)
      There is heterogeneity in the observed www.frontiersin.orgO2peak response to similar exercise training, and different exercise approaches produce variable degrees of exercise response (trainability). The aim of this study ...
    • A multimodal image guiding system for Navigated Ultrasound Bronchoscopy (EBUS): A human feasibility study 

      Sorger, Hanne; Hofstad, Erlend Fagertun; Amundsen, Tore; Langø, Thomas; Bakeng, Janne Beate Lervik; Leira, Håkon Olav (Journal article; Peer reviewed, 2017)
      Background Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is the endoscopic method of choice for confirming lung cancer metastasis to mediastinal lymph nodes. Precision is crucial for correct staging ...
    • A new procedure for automatic path planning in bronchoscopy 

      Ciobirca, C; Langø, Thomas; Gruionu, G; Leira, Håkon Olav; Gruionu, Lucian; Pastrama, SD (Journal article; Peer reviewed, 2018)
      Virtual bronchoscopy is often used for planning a real bronchoscopy procedure. Software applications are developed for virtual bronchoscopy, involving usually segmentation of the tracheobronchial tree from the medical image ...
    • A novel non-canonical Wnt signature for prostate cancer aggressiveness 

      Sandsmark, Elise; Hansen, Ailin Falkmo; Selnæs, Kirsten Margrete; Bertilsson, Helena; Bofin, Anna M.; Wright, Alan J.; Viset, Trond; Richardsen, Elin; Drabløs, Finn Sverre; Bathen, Tone Frost; Tessem, May-Britt; Rye, Morten Beck (Journal article; Peer reviewed, 2016)
      Activation of the Canonical Wnt pathway (CWP) has been linked to advanced and metastatic prostate cancer, whereas the Wnt5a-induced non-canonical Wnt pathway (NCWP) has been associated with both good and poor prognosis. A ...
    • A particular effect of sleep, but not pain or depression, on the blood-oxygen-level dependent response during working memory tasks in patients with chronic pain 

      Elvemo, Nicolas-Andreas L.; Landrø, Nils Inge; Borchgrevink, Petter Chr.; Håberg, Asta (Peer reviewed; Journal article, 2015)
      Background: Patients with chronic pain (CP) are often reported to have deficits in working memory. Pain impairs working memory, but so do depression and sleep problems, which are also common in CP. Depression has been ...
    • A PET/MRI study towards finding the optimal [18F]Fluciclovine PET protocol for detection and characterisation of primary prostate cancer. 

      Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Tessem, May-Britt; Moestue, Siver Andreas; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2016)
      Purpose: [18F]Fluciclovine PET imaging shows promise for the assessment of prostate cancer. The purpose of this PET/MRI study is to optimise the PET imaging protocol for detection and characterisation of primary prostate ...
    • A pig model of acute right ventricular afterload increase by hypoxic pulmonary vasoconstriction 

      Knai, Kathrine; Skjaervold, Nils Kristian (Journal article; Peer reviewed, 2017)
      Background: The aim of this study was to construct a non-invasive model for acute right ventricular afterload increase by hypoxic pulmonary vasoconstriction. Intact animal models are vital to improving our understanding ...
    • A Preoperative Multimarker Approach to Evaluate Acute Kidney Injury After Cardiac Surgery. 

      Enger, Tone Bull; Pleym, Hilde; Stenseth, Roar; Greiff, Guri; Wahba, Alexander; Videm, Vibeke (Journal article; Peer reviewed, 2016)
      Objective To investigate whether a multimarker strategy combining preoperative biomarkers representing distinct pathophysiologic pathways enhances preoperative risk assessment of acute kidney injury after cardiac surgery ...
    • A Prospective Population Study of Resting Heart Rate and Peak Oxygen Uptake (the HUNT Study, Norway) 

      Nauman, Javaid; Aspenes, Stian Thoresen; Nilsen, Tom Ivar Lund; Vatten, Lars Johan; Wisløff, Ulrik (Journal article; Peer reviewed, 2012)
      Objectives: We assessed the prospective association of resting heart rate (RHR) at baseline with peak oxygen uptake (VO2peak) 23 years later, and evaluated whether physical activity (PA) could modify this association. ...