Browsing Institutt for sirkulasjon og bildediagnostikk by Journals "Scientific Reports"
Now showing items 1-20 of 33
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A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders
(Peer reviewed; Journal article, 2019)The clinical significance of anti-neuronal antibodies for psychiatric disorders is controversial. We investigated if a positive anti-neuronal antibody status at admission to acute psychiatric inpatient care was associated ... -
Acute effects of high intensity training on cardiac function: a pilot study comparing subjects with type 2 diabetes to healthy controls
(Peer reviewed; Journal article, 2022)This study evaluated acute cardiac stress after a high-intensity interval training session in patients with type 2 diabetes (T2D) versus healthy controls. High intensity aerobic exercise was performed by 4 × 4-min intervals ... -
Associations between circulating microRNAs and lipid-rich coronary plaques measured with near-infrared spectroscopy
(Peer reviewed; Journal article, 2023)Lipid-rich coronary atherosclerotic plaques often cause myocardial infarction (MI), and circulating biomarkers that reflect lipid content may predict risk of MI. We investigated the association between circulating microRNAs ... -
Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling
(Journal article; Peer reviewed, 2017)The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ... -
Detection and differentiation of breast cancer sub-types using a cPLA2a activatable fluorophore
(Journal article; Peer reviewed, 2019)Cytosolic phospholipase A2α (cPLA2α) has been shown to be elevated in breast cancer and is a potential biomarker in the differentiation of molecular sub-types. Using a cPLA2α activatable fluorophore, DDAO arachidonate, we ... -
Development of risk models of incident hypertension using machine learning on the HUNT study data
(Journal article; Peer reviewed, 2024)In this study, we aimed to create an 11-year hypertension risk prediction model using data from the Trøndelag Health (HUNT) Study in Norway, involving 17 852 individuals (20–85 years; 38% male; 24% incidence rate) with ... -
Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity
(Journal article; Peer reviewed, 2018)Given the association between high aerobic capacity and the prevention of metabolic diseases, elucidating the mechanisms by which high aerobic capacity regulates whole-body metabolic homeostasis is a major research challenge. ... -
Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation
(Peer reviewed; Journal article, 2015)Understanding how metabolite levels change over the 24 hour day is of crucial importance for clinical and epidemiological studies. Additionally, the association between sleep deprivation and metabolic disorders such as ... -
Effect of bubble size on ultrasound backscatter from bubble clouds in the context of gas kick detection in boreholes
(Peer reviewed; Journal article, 2023)Early detection of gas influx in boreholes while drilling is of significant interest to drilling operators. Several studies suggest a good correlation between ultrasound backscatter/attenuation and gas volume fraction (GVF) ... -
Effect of high-fat diet and morning or evening exercise on lipoprotein subfraction profiles: secondary analysis of a randomised trial
(Journal article; Peer reviewed, 2023) -
Endothelial dysfunction in small arteries and early signs of atherosclerosis in ApoE knockout rats
(Peer reviewed; Journal article, 2020)Endothelial dysfunction is recognized as a major contributor to atherosclerosis and has been suggested to be evident far before plaque formation. Endothelial dysfunction in small resistance arteries has been suggested to ... -
Exercise prevents impaired autophagy and proteostasis in a model of neurogenic myopathy
(Journal article; Peer reviewed, 2018)Increased proteolytic activity has been widely associated with skeletal muscle atrophy. However, elevated proteolysis is also critical for the maintenance of cellular homeostasis by disposing cytotoxic proteins and ... -
Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway
(Peer reviewed; Journal article, 2022)Previous studies indicate sex differences in incidence and severity of bloodstream infections (BSI). We examined the effect of sex on risk of BSI, BSI mortality, and BSI caused by the most common infecting bacteria. Using ... -
Genetic risk score associations for myocardial infarction are comparable in persons with and without rheumatoid arthritis: the population-based HUNT study
(Peer reviewed; Journal article, 2020)Persons with rheumatoid arthritis (RA) have increased risk of myocardial infarction (MI). Overlapping associations with MI of weighted genetic risk scores (wGRS) for coronary artery disease (CAD) and RA is unknown in a ... -
Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma
(Journal article; Peer reviewed, 2018)Reactive stroma is a tissue feature commonly observed in the tumor microenvironment of prostate cancer and has previously been associated with more aggressive tumors. The aim of this study was to detect differentially ... -
Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study
(Journal article; Peer reviewed, 2022) -
NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA
(Peer reviewed; Journal article, 2023)A cost-effective, viral nucleic acid (NA) isolation kit based on NAxtra magnetic nanoparticles was developed at the Norwegian University of Science and Technology in response to the shortage of commercial kits for isolation ... -
O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes
(Journal article; Peer reviewed, 2019)Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the ... -
Outdoor artificial light at night, air pollution, and risk of childhood acute lymphoblastic leukemia in the California Linkage Study of Early-Onset Cancers
(Peer reviewed; Journal article, 2023)Acute lymphoblastic leukemia (ALL) is the most common type of cancer in children (age 0–14 years); however, the etiology remains incompletely understood. Several environmental exposures have been linked to risk of childhood ... -
Raidionics: an open software for pre- and postoperative central nervous system tumor segmentation and standardized reporting
(Peer reviewed; Journal article, 2023)For patients suffering from central nervous system tumors, prognosis estimation, treatment decisions, and postoperative assessments are made from the analysis of a set of magnetic resonance (MR) scans. Currently, the lack ...