• Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations 

      Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Peer reviewed; Journal article, 2021)
      Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ...
    • Dyslipidemia and Risk of Preeclampsia: A Multiancestry Mendelian Randomization Study 

      Hosier, Hillary; Lipkind, Heather S.; Rasheed, Humaira; Dewan, Andrew T.; Rogne, Tormod (Journal article; Peer reviewed, 2023)
      Preeclampsia is a leading cause of maternal morbidity, and dyslipidemia has been associated with preeclampsia in observational studies. We use Mendelian randomization analyses to estimate the association between lipid ...
    • Metabolomics identifies placental dysfunction and confirms Flt-1 (FMS-like tyrosine kinase receptor 1) biomarker specificity 

      Austdal, Marie; Silva, Gabriela; Bowe, Sophie; Thomsen, Liv Cecilie Vestrheim; Tangerås, Line Haugstad; Bjørge, Line; Bathen, Tone Frost; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2019)
      Clinical end-stage parameters define the pregnancy disorders preeclampsia and fetal growth restriction while classification of the underlying placental dysfunction is missing and urgently needed. Flt-1 (FMS-like tyrosine ...
    • Relationship between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses 

      Malik, Rainer; Georgakis, Marios K.; Vujkovic, Marijana; Damrauer, Scott M.; Elliott, Paul; Karhunen, Ville; Giontella, Alice; Fava, Cristiano; Hellwege, Jacklyn N.; Shuey, Megan M.; Edwards, Todd L.; Rogne, Tormod; Åsvold, Bjørn Olav; Brumpton, Ben Michael; Burgess, Stephen; Dichgans, Martin; Gill, Dipender (Peer reviewed; Journal article, 2021)
      Observational studies exploring whether there is a nonlinear effect of blood pressure on cardiovascular disease (CVD) risk are hindered by confounding. This limitation can be overcome by leveraging randomly allocated genetic ...