Blar i Institutt for sirkulasjon og bildediagnostikk på tidsskrift "Breast Cancer Research"
Viser treff 1-4 av 4
-
DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival
(Peer reviewed; Journal article, 2022)Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ... -
Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer
(Journal article; Peer reviewed, 2019)Introduction Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 ... -
Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
(Journal article; Peer reviewed, 2017)Background Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify integrated ... -
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
(Journal article; Peer reviewed, 2014)Introduction Dysregulated choline metabolism is a well-known feature of breast cancer, but the underlying mechanisms are not fully understood. In this study, the metabolomic and transcriptomic characteristics of a large ...