• 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...
    • 18F-FACBC PET/MRI in the evaluation of human brain metastases: a case report 

      Johannessen, Knut; Berntsen, Erik Magnus; Johansen, Håkon; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2021)
      Abstract Background: Patients with metastatic cancer to the brain have a poor prognosis. In clinical practice, MRI is used to delineate, diagnose and plan treatment of brain metastases. However, MRI alone is limited in ...
    • A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders 

      Schou, Morten Brix; Sæther, Sverre Georg; Drange, Ole Kristian; Brenner, Eiliv; Crespi, Joan Vidal; Eikenes, Live; Mykland, Martin Syvertsen; Pintzka, Carl Wolfgang Schøyen; Håberg, Asta; Sand, Trond; Vaaler, Arne; Kondziella, Daniel (Peer reviewed; Journal article, 2019)
      The clinical significance of anti-neuronal antibodies for psychiatric disorders is controversial. We investigated if a positive anti-neuronal antibody status at admission to acute psychiatric inpatient care was associated ...
    • Acute Diffusion Tensor and Kurtosis Imaging and Outcome following Mild Traumatic Brain Injury 

      Stenberg, Jonas; Eikenes, Live; Moen, Kent Gøran; Vik, Anne; Håberg, Asta; Skandsen, Toril (Peer reviewed; Journal article, 2021)
      In this prospective cohort study, we investigated associations between acute diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) metrics and persistent post-concussion symptoms (PPCS) 3 months after mild ...
    • Acute thalamic connectivity precedes chronic post-concussive symptoms in mild traumatic brain injury 

      Woodrow, Rebecca E; Winzeck, Stefan; Luppi, Andrea I; Kelleher-Unger, Isaac R; Spindler, Lennart R B; Wilson, J T Lindsay; Newcombe, Virginia F.J.; Coles, Jonathan P; Menon, David K; Stamatakis, Emmanuel A; Amrein, Krisztina; Andelic, Nada; Frisvold, Shirin K; Anke, Audny Gabriele Wagner; Andreassen, Lasse; Azouvi, Philippe; Bellander, Bo- Michael; Benali, Habib; Caccioppola, Alessio; Buki, Andras; Calappi, Emiliana; Citerio, Guiseppe; Carbonara, Marco; Clusmann, Hans; Coburn, Mark; Coles, Jonathan; Correia, Marta; Czeiter, Endre; De Keyser, Véronique; Degos, Vincent; Depreitere, Bart; Eikenes, Live; Ezer, Erzsébet; Foks, Kelly; Ghuysen, Alexandre; Galanaud, Damien; Glocker, Ben; Håberg, Asta; Haitsma, Iain; Helseth, Eirik; Hutchinson, Peter J.; Kornaropoulos, Evgenios; Kovács, Noémi; Kowark, Ana; Laureys, Steven; Ledoux, Didier; Lingsma, Hester; Maas, Andrew I. R.; Manley, Geoffrey; Menovsky, Tomas; Misset, Benoit; Muraleedharan, Visakh; Nakken, Ingeborg; Nordhøy, Wibeke; Nyirádi, József; Ortolano, Fabrizio; Parizel, Paul M.; Perlbarg, Vincent; Persona, Paolo; Peul, Wilco; Posti, Jussi P.; Puybasset, Louis; Richter, Sophie; Røe, Cecilie; Røise, Olav; Rossaint, Rolf; Rossi, Sandra; Rueckert, Daniel; Skandsen, Toril; Sorinola, Abayomi; Steyerberg, Ewout W; Stocchetti, Nino; Takala, Riikka; Tamás, Viktória; Tenovuo, Olli; Vámos, Zoltán; Van der Steen, Gregory; Van Hecke, Wim; Vande Vyvere, Thijs; Verheyden, Jan; Vik, Anne; Volovici, Victor; Westlye, Lars Tjelta; Williams, Guy; Ylen, Peter; Zoerle, Tommaso (Journal article; Peer reviewed, 2023)
      Chronic post-concussive symptoms are common after mild traumatic brain injury (mTBI) and are difficult to predict or treat. Thalamic functional integrity is particularly vulnerable in mTBI and may be related to long-term ...
    • AI-driven attenuation correction for brain PET/MRI: Clinical evaluation of a dementia cohort and importance of the training group size 

      Ladefoged, Claes Nøhr; Hansen, Adam Espe; Henriksen, Otto Mølby; Bruun, Frederik Jager; Eikenes, Live; Øen, Silje Kjærnes; Karlberg, Anna Maria; Højgaard, Liselotte; Law, Ian; Andersen, Flemming Littrup (Peer reviewed; Journal article, 2020)
      Introduction Robust and reliable attenuation correction (AC) is a prerequisite for accurate quantification of activity concentration. In combined PET/MRI, AC is challenged by the lack of bone signal in the MRI from which ...
    • Atypical brain structure mediates reduced IQ in young adults born preterm with very low birth weight 

      Rimol, Lars Morten; Rise, Henning Hoel; Evensen, Kari Anne Indredavik; Yendiki, Anastasia; Løhaugen, Gro; Indredavik, Marit Sæbø; Brubakk, Ann-Mari; Bjuland, Knut Jørgen; Eikenes, Live; Weider, Siri; Håberg, Asta; Skranes, Jon Sverre (Peer reviewed; Journal article, 2022)
      Preterm birth with very low birth weight (VLBW) confers heightened risk for perinatal brain injury and long-term cognitive deficits, including a reduction in IQ of up to one standard deviation. Persisting gray and white ...
    • Both brain size and biological sex contribute to variation in white matter microstructure in middle-aged healthy adults 

      Eikenes, Live; Visser, Eelke; Vangberg, Torgil Riise; Håberg, Asta (Peer reviewed; Journal article, 2022)
      Whether head size and/or biological sex influence proxies of white matter (WM) microstructure such as fractional anisotropy (FA) and mean diffusivity (MD) remains controversial. Diffusion tensor imaging (DTI) indices are ...
    • A comparison of FDG PET/MR and PET/CT for staging, response assessment, and prognostic imaging biomarkers in lymphoma 

      Husby, Trine; Johansen, Håkon; Bogsrud, Trond; Hustad, Kari Vekseth; Evensen, Birte Veslemøy; Boellard, Ronald; Giskeødegård, Guro F.; Fagerli, Unn-Merete; Eikenes, Live (Peer reviewed; Journal article, 2022)
      The aim of the current study was to investigate the diagnostic performance of FDG PET/MR compared to PET/CT in a patient cohort including Hodgkins lymphoma, diffuse large B-cell lymphoma, and high-grade B-cell lymphoma at ...
    • Diagnostic accuracy of anti-3-[18F]-FACBC PET/MRI in gliomas 

      Karlberg, Anna Maria; Pedersen, Lars Kjelsberg; Vindstad, Benedikte Emilie; Skjulsvik, Anne Jarstein; Johansen, Håkon; Solheim, Ole Skeidsvoll; Skogen, Karoline; Kvistad, Kjell Arne; Bogsrud, Trond; Myrmel, Kristin Smistad; Giskeødegård, Guro F.; Ingebrigtsen, Tor; Berntsen, Erik Magnus; Eikenes, Live (Peer reviewed; Journal article, 2023)
      Purpose - The primary aim was to evaluate whether anti-3-[18F]FACBC PET combined with conventional MRI correlated better with histomolecular diagnosis (reference standard) than MRI alone in glioma diagnostics. The ability ...
    • Diagnostic Value of 18F-FACBC PET/MRI in Brain Metastases 

      Øen, Silje Kjærnes; Johannessen, Knut; Pedersen, Lars Kjelsberg; Berntsen, Erik Magnus; Totland, Jon Andre; Johansen, Håkon; Bogsrud, Trond Velde; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2022)
      Purpose The study aims to evaluate whether combined 18F-FACBC PET/MRI could provide additional diagnostic information compared with MRI alone in brain metastases. Patients and Methods Eighteen patients with newly ...
    • Diffusion kurtosis imaging in mild traumatic brain injury and postconcussional syndrome 

      Karlsen, Rune Hatlestad; Einarsen, Cathrine Elisabeth; Moe, Hans Kristian; Håberg, Asta; Vik, Anne; Skandsen, Toril; Eikenes, Live (Journal article; Peer reviewed, 2019)
      ims of this study were to investigate white matter (WM) and thalamus microstructure 72 hr and 3 months after mild traumatic brain injury (TBI) with diffusion kurtosis imaging (DKI) and diffusion tensor imaging (DTI), and ...
    • Diffusion Tensor and Kurtosis Imaging Findings the First Year Following Mild Traumatic Brain Injury 

      Stenberg, Jonas; Skandsen, Toril; Moen, Kent Gøran; Vik, Anne; Eikenes, Live; Håberg, Asta (Journal article; Peer reviewed, 2022)
    • Diffusion tensor imaging in middle-aged headache sufferers in the general population: A cross-sectional population-based imaging study in the Nord-Trøndelag health study (HUNT-MRI) 

      Husøy, Andreas Kattem; Eikenes, Live; Håberg, Asta; Hagen, Knut; Stovner, Lars Jacob (Journal article; Peer reviewed, 2019)
      Background Several studies have investigated white matter with diffusion tensor imaging (DTI) in those suffering from headache, but so far only in clinic based samples and with conflicting results. Methods In the present ...
    • Effects of a 5-Year Exercise Intervention on White Matter Microstructural Organization in Older Adults. A Generation 100 Substudy 

      Pani, Jasmine; Eikenes, Live; Reitlo, Line Skarsem; Stensvold, Dorthe; Wisløff, Ulrik; Håberg, Asta (Peer reviewed; Journal article, 2022)
      Aerobic fitness and exercise could preserve white matter (WM) integrity in older adults. This study investigated the effect on WM microstructural organization of 5 years of exercise intervention with either supervised ...
    • How Does the Accuracy of Intracranial Volume Measurements Affect Normalized Brain Volumes? Sample Size Estimates Based on 966 Subjects from the HUNT MRI Cohort 

      Hansen, Tor Ivar; Brezova, Veronika; Eikenes, Live; Håberg, Asta; Vangberg, Torgil Riise (Peer reviewed; Journal article, 2015)
      BACKGROUND AND PURPOSE: The intracranial volume is commonly used for correcting regional brain volume measurements for variations in head size. Accurate intracranial volume measurements are important because errors will ...
    • Image Quality and Detectability in Siemens Biograph PET/MRI and PET/CT Systems - A Phantom study 

      Øen, Silje Kjærnes; Aasheim, Lars Birger; Eikenes, Live; Karlberg, Anna Maria (Journal article; Peer reviewed, 2019)
      Background The technology of modern positron emission tomography (PET) systems continuously improving, and with it the possibility to detect smaller lesions. Since first introduced in 2010, the number of hybrid PET/magnetic ...
    • Incidental Intracranial Findings and Their Clinical Impact; The HUNT MRI Study in a General Population of 1006 Participants between 50-66 Years 

      Håberg, Asta; Hammer, Tommy Arild; Kvistad, Kjell Arne; Jana, Rydland; Müller, Tomm Brostrup; Eikenes, Live; Gårseth, Mari; Stovner, Lars Jacob (Journal article; Peer reviewed, 2016)
      Objectives Evaluate types and prevalence of all, incidental, and clinically relevant incidental intracranial findings, i.e. those referred to primary physician or clinical specialist, in a cohort between 50 and 66 years ...
    • Limited microstructural and connectivity deficits despite subcortical volume reductions in school-aged children born preterm with very low birth weight. 

      Sølsnes, Anne Elisabeth; Sripada, Kam; Yendiki, Anastasia; Bjuland, Knut Jørgen; Østgård, Heidi Furre; Aanes, Synne; Grunewaldt, Kristine Hermansen; Løhaugen, Gro; Eikenes, Live; Håberg, Asta; Rimol, Lars Morten; Skranes, Jon Sverre (Journal article; Peer reviewed, 2015)
      Preterm birth and very low birth weight (VLBW, ≤ 1500 g) are worldwide problems that burden survivors with lifelong cognitive, psychological, and physical challenges. In this multimodal structural magnetic resonance imaging ...
    • Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Myrthue, Mariane Olesen; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Esmaeili, Morteza; Dai, Hong Yan; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2017)
      Background Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, ...