• Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway 

      Mohus, Randi Marie; Gustad, Lise Tuset; Furberg, Anne-Sofie; Moen, Martine Kjølberg; Liyanarachi, Kristin Vardheim; Askim, Åsa Susanne; Åsberg, Signe Elisabeth; DeWan, Andrew T.; Rogne, Tormod; Simonsen, Gunnar Skov; Nilsen, Tom Ivar Lund; Åsvold, Bjørn Olav; Damås, Jan Kristian; Solligård, Erik (Peer reviewed; Journal article, 2022)
      Previous studies indicate sex differences in incidence and severity of bloodstream infections (BSI). We examined the effect of sex on risk of BSI, BSI mortality, and BSI caused by the most common infecting bacteria. Using ...
    • Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection 

      Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Kim, Haelin; Marstad, Anne; Åsberg, Signe Elisabeth; Strand, Trine Aakvik; Haug, Markus; Niederweis, Michael; Stenmark, Harald Alfred; Flo, Trude Helen (Peer reviewed; Journal article, 2020)
      Mycobacterium tuberculosis is a global health problem in part as a result of extensive cytotoxicity caused by the infection. Here, we show how M. tuberculosis causes caspase-1/NLRP3/gasdermin D-mediated pyroptosis of human ...