Blar i Institutt for sirkulasjon og bildediagnostikk på forfatter "Kaasa, Stein"
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The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain 11 Medical and Health Sciences 1103 Clinical Sciences
Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2018)Background Radiation therapy (RT) results in pain relief for about 6 of 10 patients with cancer induced bone pain (CIBP) caused by bone metastases. The high number of non-responders, the long median time from RT to pain ... -
The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses
Skorpen, Frank; von Hofacker, Sebastian; Bjørngaard, Mads; Skogholt, Anne Heidi; Dale, Ola; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2016)BACKGROUND: Genetic variability contributes to variable clinical response to opioids. This study emerged from the observation of three Norwegian patients who showed no or extraordinary poor response to very high doses of ... -
Which factors can aid clinicians to identify a risk of pain during the following month in patients with bone metastases? A longitudinal analyses
Habberstad, Ragnhild H; Hjermstad, Marianne Jensen; Brunelli, Cinzia; Kaasa, Stein; Bennett, Michael I; Pardon, Koen; Klepstad, Pål (Journal article; Peer reviewed, 2018)Purpose Explore clinical factors associated with higher pain intensity and future pain in patients with bone metastases to identify patients who can benefit from closer follow-up or pain-modifying interventions. Methods This ... -
Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer-a double-blind, randomized placebo-controlled clinical multicenter phase IV trial
Jakobsen, Gunnhild; Sjue, Karin; Paulsen, Ørnulf; Kaasa, Stein; Hjermstad, Marianne Jensen; Klepstad, Pål (Peer reviewed; Journal article, 2022)Purpose: Insomnia is frequent in patients with advanced cancer, and a variety of pharmacological agents is used to treat this condition. Still, few clinical trials have investigated the effectiveness of pharmacological ... -
Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer: study protocol for a double-blind, randomized, placebo-controlled, clinical multicenter trial
Jakobsen, Gunnhild; Engstrøm, Morten; Paulsen, Ørnulf; Sjue, Karin; Raj, Sunil Xavier; Thronæs, Morten; Hjermstad, Marianne Jensen; Kaasa, Stein; Fayers, Peter; Klepstad, Pål (Journal article; Peer reviewed, 2018)Background Despite the high prevalence of insomnia in patients with advanced cancer, there are no randomized controlled trials on pharmacological interventions for insomnia in this group of patients. A variety of ...