Blar i Institutt for samfunnsmedisin og sykepleie på tidsskrift "Tumour Biology"

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    • The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer 

      Lønning, Per Eystein; Gansmo, Liv Beathe; Salvesen, Helga; Romundstad, Pål Richard; Birkeland, Einar Elvbakken; Bjørnslett, Merete Pauline; Halle, Mari Kyllesø; Dørum, Anne; Hveem, Kristian; Knappskog, Stian; Vatten, Lars Johan (Journal article; Peer reviewed, 2016)
      The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in ...