Blar i Institutt for samfunnsmedisin og sykepleie på forfatter "Gabrielsen, Maiken Elvestad"

Viser treff 41-45 av 45

    • The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study 

      Bjørngaard, Johan Håkon; Gunnell, David; Gabrielsen, Maiken Elvestad; Davey Smith, George; Skorpen, Frank; Krokan, Hans Einar; Vatten, Lars Johan; Romundstad, Pål Richard (Journal article; Peer reviewed, 2013)
      Cigarette smoking is strongly associated with mental illness but the causal direction of the association is uncertain. We investigated the causal relationship between smoking and symptoms of anxiety and depression in the ...

    • The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT study 

      Johnsen, Marianne Bakke; Vie, Gunnhild Åberge; Winsvold, Bendik K S; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Pedersen, Linda Margareth; Hellevik, Alf Inge; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Skorpen, Frank; Romundstad, Pål Richard; Storheim, Kjersti; Nordsletten, Lars; Zwart, John-Anker (Journal article; Peer reviewed, 2017)
      Objective Smoking has been associated with a reduced risk of hip and knee osteoarthritis (OA) and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely to be ...

    • Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2 

      Fan, Yanbo; Wolford, Brooke N.; Lu, Haocheng; Liang, Wenying; Sun, Jinjian; Zhou, Wei; Rom, Oren; Mahajan, Anubha; Surakka, Ida; Graham, Sarah E.; Liu, Zhipeng; Kim, Hyunbae; Ramdas, Shweta; Fritsche, Lars; Nielsen, Jonas B.; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Yang, Dongshan; Song, Jun; Garcia-Barrio, Minerva T.; Zhang, Jifeng; Liu, Wanqing; Zhang, Kezhong; Willer, Cristen J.; Chen, Y. Eugene (Peer reviewed; Journal article, 2021)
      The rs58542926C >T (E167K) variant of the transmembrane 6 superfamily member 2 gene (TM6SF2) is associated with increased risks for nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). Nevertheless, the role ...

    • Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index 

      Hartley, April; Sanderson, Eleanor; Granell, Raquel; Paternoster, Lavinia; Zheng, Jie; Smith, George Davey; Southam, Lorraine; Hatzikotoulas, Konstantinos; Boer, Cindy G.; Van Meurs, Joyce; Zeggini, Eleftheria; Gregson, Celia L.; Tobias, Jon H.; Stefánsdóttir, Lilja; Zhang, Yanfei; De Almeida, Rodrigo Coutinho; Wu, Tian T.; Teder-Laving, Maris; Skogholt, Anne Heidi; Terao, Chikashi; Zengini, Eleni; Alexiadis, George; Barysenka, Andrei; Bjornsdottir, Gyda; Gabrielsen, Maiken Elvestad; Gilly, Arthur; Ingvarsson, Thorvaldur; Johnsen, Marianne Bakke; Jonsson, Helgi Freyr; Kloppenburg, Margreet G.; Luetge, Almut; Mägi, Reedik; Mangino, Massimo; Nelissen, Rob R.G.H.H.; Shivakumar, Manu; Steinberg, Julia; Takuwa, Hiroshi; Thomas, Laurent; Tuerlings, Margo; Babis, George; Cheung, Jason Pui Yin; Samartzis, Dino; Lietman, Steve A.; Slagboom, P. Eline; Stefansson, Kari; Uitterlinden, André G.; Winsvold, Bendik K S; Zwart, John Anker Henrik; Sham, Pak Chung; Thorleifsson, Gudmar; Gaunt, Tom R.; Morris, Andrew P.; Valdes, Ana M.; Tsezou, Aspasia; Cheah, Kathryn S.E.; Ikegawa, Shiro; Hveem, Kristian; Esko, Tõnu; Wilkinson, J. Mark; Meulenbelt, Ingrid; Michael Lee, Ming Ta; Styrkársdóttir, Unnur (Peer reviewed; Journal article, 2022)
      Objectives Observational analyses suggest that high bone mineral density (BMD) is a risk factor for osteoarthritis (OA); it is unclear whether this represents a causal effect or shared aetiology and whether these ...

    • Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition 

      Brumpton, Ben Michael; Fritsche, Lars; Zheng, Jie; Nielsen, Jonas Bille; Mannila, Maria Nastase; Surakka, Ida; Rasheed, Humaira; Vie, Gunnhild Åberge; Graham, Sarah E.; Gabrielsen, Maiken Elvestad; Laugsand, Lars Erik; Aukrust, Pål; Vatten, Lars Johan; Damås, Jan Kristian; Ueland, Thor; Janszky, Imre; Zwart, John-Anker; van't Hooft, Ferdinand M.; Seidah, Nabil Georges; Hveem, Kristian; Willer, Cristen; Smith, George Davey; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2019)
      PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce serum LDL (low-density lipoprotein) cholesterol (LDL-C) by increasing uptake in the liver. Although some long-term trials have evaluated their safety, ...