• Assessment of kallikrein 6 as a cross-sectional and longitudinal biomarker for Alzheimer's disease 

      Patra, Kalicharan; Soosaipillai, Antoninus; Sando, Sigrid Botne; Lauridsen, Camilla; Berge, Guro; Møller, Ina; Grøntvedt, Gøril Rolfseng; Bråthen, Geir; Begcevic, Ilijana; Moussaud, Simon; Minthon, Lennart; Hansson, Oskar; Diamandis, Eleftherios P.; White, Linda Rosemary; Nielsen, Henrietta M. (Journal article; Peer reviewed, 2018)
      Background Kallikrein 6 (KLK6) is known to be an age-related protease expressed at high levels in the central nervous system. It was previously shown to be involved in proteolysis of extracellular proteins implicated in ...
    • Association between blood pressure and Alzheimer disease measured up to 27 years prior to diagnosis: the HUNT Study 

      Gabin, Jessica Mira; Tambs, Kristian; Saltvedt, Ingvild; Sund, Erik; Holmen, Jostein (Journal article; Peer reviewed, 2017)
      Background A lot of attention has been paid to the relationship of blood pressure and dementia because epidemiological research has reported conflicting evidence. Observational data has shown that midlife hypertension is ...
    • Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer’s disease 

      Giannisis, Andreas; Al-Grety, Asma; Carlsson, Henrik; Patra, Kalicharan; Twohig, Daniel; Sando, Sigrid Botne; Lauridsen, Camilla; Berge, Guro; Grøntvedt, Gøril Rolfseng; Bråthen, Geir; White, Linda Rosemary; Kultima, Kim; Nielsen, Henrietta M. (Peer reviewed; Journal article, 2022)
      Background Low levels of plasma apolipoprotein E (apoE) and presence of the APOE ε4 allele are associated with an increased risk of Alzheimer’s disease (AD). Although the increased risk of AD in APOE ε4-carriers is ...