• Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial 

      Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)
      Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ...
    • How well do neurosurgeons predict survival in patients with high-grade glioma? 

      Sagberg, Lisa Millgård; Jakola, Asgeir S.; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2021)
      Due to the lack of reliable prognostic tools, prognostication and surgical decisions largely rely on the neurosurgeons’ clinical prediction skills. The aim of this study was to assess the accuracy of neurosurgeons’ prediction ...
    • Lower-Grade Gliomas: An Epidemiological Voxel-Based Analysis of Location and Proximity to Eloquent Regions 

      Gómez Vecchio, Tomás; Neimantaite, Alice; Corell, Alba; Bartek, Jiri; Jensdottir, Margret; Reinertsen, Ingerid; Solheim, Ole; Jakola, Asgeir S. (Peer reviewed; Journal article, 2021)
      Background: Glioma is the most common intra-axial tumor, and its location relative to critical areas of the brain is important for treatment decision-making. Studies often report tumor location based on anatomical taxonomy ...
    • Preoperative Brain Tumor Imaging: Models and Software for Segmentation and Standardized Reporting 

      Bouget, David Nicolas Jean-Mar; Pedersen, André; Jakola, Asgeir S.; Kavouridis, Vasileios; Emblem, Kyrre Eeg; Eijgelaar, Roelant S; Kommers, Ivar; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Nibali, Marco Conti; Furtner, Julia; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Kloet, Alfred; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre A; Rossi, Marco; Sciortino, Tommaso; van den Brink, Wimar A.; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Hamer, Philip C De Witt; Solheim, Ole; Reinertsen, Ingerid (Peer reviewed; Journal article, 2022)
      For patients suffering from brain tumor, prognosis estimation and treatment decisions are made by a multidisciplinary team based on a set of preoperative MR scans. Currently, the lack of standardized and automatic methods ...
    • Surgical management of lumbar spinal stenosis: Observational studies based on the Norwegian registry for spine surgery 

      Nerland, Ulf Skule (Doctoral thesis at NTNU;2016:50, Doctoral thesis, 2016)
      SUMMARY: This doctoral thesis deals with the surgical management of lumbar spinal stenosis (LSS), a disease in the spinal column. This is a degenerative condition with reduced space in the spinal canal due to age-related ...