• Long-Term Outcomes of Genetic Parkinson's Disease 

      Aasly, Jan (Journal article, 2020)
      Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects 1-2% of people by the age of 70 years. Age is the most important risk factor, and most cases are sporadic without any known environmental ...
    • Long-term posttraumatic stress after disaster: A controlled study of survivors’ health 27 years after the capsized North Sea oil rig 

      Bøe, Hans Jakob (Doktoravhandlinger ved NTNU, 1503-8181; 2011:244, Doctoral thesis, 2011)
      Vedvarende posttraumatisk stress: en kontrollert studie av overlevendes helse 27 år etter Alexander L. Kielland ulykken Alexander L. Kielland ulykken i 1980 kostet 123 menn livet, bare 89 overlevde. Kort tid etter ble ...
    • Long-Term Results After Surgery for Degenerative Cervical Myelopathy 

      Johansen, Tonje Okkenhaug; Holmberg, Siril Therese; Danielsen, Elisabet; Rao, Vidar; Salvesen, Øyvind Olav; Andresen, Hege; Carmen, Vleggeert-Lankamp; Solberg, Tore; Gulati, Sasha; Nygaard, Øystein Petter (Peer reviewed; Journal article, 2023)
      BACKGROUND AND OBJECTIVES: Degenerative cervical myelopathy (DCM) is a frequent cause of spinal cord dysfunction, and surgical treatment is considered safe and effective. Long-term results after surgery are limited. ...
    • The Long-Term Risk of Knee Arthroplasty in Patients with Arthroscopically Verified Focal Cartilage Lesions : A Linkage Study with the Norwegian Arthroplasty Register, 1999 to 2020 

      Birkenes, Thomas; Furnes, Ove Nord; Lygre, Stein Håkon Låstad; Solheim, Eirik Johan; Årøen, Asbjørn; Knutsen, Gunnar; Drogset, Jon Olav; Heir, Stig; Engebretsen, Lars; Løken, Sverre Bertrand; Visnes, Håvard (Journal article; Peer reviewed, 2023)
      Background: Focal cartilage lesions are common in the knee. The risk of later ipsilateral knee arthroplasty remains unknown. The purposes of the present study were to evaluate the long-term cumulative risk of knee arthroplasty ...
    • Long-term temporal trends in incidence rate and case fatality of sepsis and COVID-19-related sepsis in Norwegian hospitals, 2008-2021: a nationwide registry study 

      Skei, Nina Vibeche; Nilsen, Tom Ivar Lund; Knoop, Siri Tandberg; Prescott, Hallie; Lydersen, Stian; Mohus, Randi Marie; Brkic, Alen; Liyanarachi, Kristin Vardheim; Solligård, Erik; Damås, Jan Kristian; Gustad, Lise Tuset (Peer reviewed; Journal article, 2023)
      Objectives To estimate temporal trends in incidence rate (IR) and case fatality during a 14-year period from 2008 to 2021, and to assess possible shifts in these trends during the COVID-19 pandemic. Setting All Norwegian ...
    • Long-term work outcomes and the efficacy of multidisciplinary rehabilitation programs on labor force participation in cancer patients - a protocol for a longitudinal prospective cohort study 

      Engan, Harald; Oldervoll, Line Merethe; Bertheussen, GF; Gaarder, MH; Nielsen, Roy; Paraponaris, Alain; Stene, GB; Tandstad, Torgrim; Torp, Steffen (Journal article; Peer reviewed, 2020)
      Background. Many cancer survivors experience late effects of cancer treatment and therefore struggle to return to work. Norway provides rehabilitation programs to increase labor force participation for cancer survivors ...
    • Longer Length of First Stay in Intermittent Residential Programmes Is Associated with Larger Weight Loss at 1 and 2 Years 

      Martins, Catia; Strømmen, Magnus; Kulseng, Bård (Journal article; Peer reviewed, 2013)
      Objective: To determine if length of first stay impacts on weight loss and cardiovascular fitness, at 1 and 2 years in severely obese patients enrolled in intermittent residential programs. Methods: In a retrospective ...
    • Longitudinal Associations Between Persistent Post-Concussion Symptoms and Blood Biomarkers of Inflammation and CNS-Injury Following Mild Traumatic Brain Injury 

      Clarke, Gerard Janez; Skandsen, Toril; Zetterberg, Henrik; Follestad, Turid; Einarsen, Cathrine Elisabeth; Vik, Anne; Mollnes, Tom Eirik; Pischke, Soeren; Blennow, Kaj; Håberg, Asta (Peer reviewed; Journal article, 2023)
      The aim of our study was to investigate the biological underpinnings of persistent post-concussion symptoms (PPCS) at 3 months following mild traumatic brain injury (mTBI). Patients (n = 192, age 16–60 years) with mTBI, ...
    • Longitudinal brain age prediction and cognitive function after stroke 

      Aamodt, Eva Birgitte; Alnæs, Dag; de Lange, Ann-Marie Glasø; Aam, Stina; Schellhorn, Till; Saltvedt, Ingvild Tina; Beyer, Mona Kristiansen; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2022)
      Advanced age is associated with post-stroke cognitive decline. Machine learning based on brain scans can be used to estimate brain age of patients, and the corresponding difference from chronological age, the brain age gap ...
    • Longitudinal Brain Changes After Stroke and the Association With Cognitive Decline 

      Aamodt, Eva Birgitte; Lydersen, Stian; Alnæs, Dag; SCHELLHORN, TILL; Saltvedt, Ingvild; Beyer, Mona K.; Håberg, Asta (Peer reviewed; Journal article, 2022)
      Background: Cognitive impairment is common after stroke. So is cortical- and subcortical atrophy, with studies reporting more atrophy in the ipsilesional hemisphere than the contralesional hemisphere. The current study ...
    • Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease 

      Nordengen, Kaja; Kirsebom, Bjørn-Eivind Seljelid; Richter, Grit; Pålhaugen, Lene; Gisladottir, Berglind; Siafarikas, Nikias Ioannis; Nakling, Arne Exner; Rongve, Arvid; Bråthen, Geir; Grøntvedt, Gøril Rolfseng; Gonzalez, Fernando; Waterloo, Knut; Sharma, Kulbhushan; Karikari, Thomas; Vromen, Eleonora M.; Tijms, Betty M.; Visser, Pieter J.; Selnes, Per; Kramberger, Milicia G.; Winblad, Bengt; Blennow, Kaj; Fladby, Tormod (Peer reviewed; Journal article, 2023)
      Background Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal ...
    • Longitudinal Changes in Circulating Metabolites and Lipoproteins After Breast Cancer Treatment 

      Giskeødegård, Guro F.; Madssen, Torfinn Støve; Sangermani, Matteo; Lundgren, Steinar; Wethal, Torgeir; Andreassen, Trygve; Reidunsdatter, Randi Johansen; Bathen, Tone Frost (Peer reviewed; Journal article, 2022)
      The multimodal treatment of breast cancer may induce long term effects on the metabolic profile and increase the risk of future cardiovascular disease. In this study, we characterized longitudinal changes in serum lipoprotein ...
    • Longitudinal high-density EEG study of looming in full-term and preterm infants 

      Nouman, Arshia (Master thesis, 2013)
      Electroencephalogram (EEG) was used on full-term and preterm infants at the age of 5 months and again at the age of 12 months to investigate brain electrical activity as a function of looming visual stimuli on a collision ...
    • Longitudinal looming study in infants using high-density EEG 

      Soltvedt, Lisa Marie (Master thesis, 2013)
      A rapidly approaching object provides information about the object’s approach and how imminent a collision is. Prospective control when responding to a looming object approaching on a direct collision course was studied ...
    • Longitudinal Monitoring of Parkinson's Disease in Different Ethnic Cohorts: The DodoNA and LONG-PD Study 

      Markopoulou, Katerina; Aasly, Jan; Ju Chung, Sun; Dardiotis, Efthimios; Wirdefeldt, Karin; Premkumar, Ashvini; Schoneburg, Bernadette; Kartha, Ninith; Wilk, Gary; Wei, Jun Rong; Simon, Kelly Claire; Tideman, Samuel; Epshteyn, Alexander; Hadsell, Bryce; Garduno, Lisette; Pham, Anna; Frigerio, Roberta; Maraganore, Demetrius M. (Peer reviewed; Journal article, 2020)
      Background: Different factors influence severity, progression, and outcomes in Parkinson's disease (PD). Lack of standardized clinical assessment limits comparison of outcomes and availability of well-characterized cohorts ...
    • Longitudinal study of the effect of a 5-year exercise intervention on structural brain complexity in older adults. A Generation 100 substudy 

      Pani, Jasmine; Marzi, Chiara; Stensvold, Dorthe; Wisløff, Ulrik; Håberg, Asta; Diciotti, Stefano (Peer reviewed; Journal article, 2022)
      Physical inactivity has been identified as an important risk factor for dementia. High levels of cardiorespiratory fitness (CRF) have been shown to reduce the risk of dementia. However, the mechanism by which exercise ...
    • Longitudinal trajectories of functional recovery after hip fracture 

      Dakhil, Shams; Saltvedt, Ingvild Tina; Saltyte Benth, Jurate; Thingstad, Anne Pernille Mæhle; Watne, Leiv; Wyller, Torgeir Bruun; Helbostad, Jorunn Hege Lægdheim; Frihagen, Frede; Johnsen, Lars Gunnar; Taraldsen, Kristin (Peer reviewed; Journal article, 2023)
      Background There is limited evidence regarding predictors of functional trajectories after hip fracture. We aimed to identify groups with different trajectories of functional recovery the first year after hip fracture, ...
    • Long‐term changes in self‐reported sleep quality and risk of chronic musculoskeletal pain: The HUNT Study 

      Skarpsno, Eivind S.; Nilsen, Tom Ivar Lund; Hagen, Knut; Mork, Paul Jarle (Peer reviewed; Journal article, 2021)
      We examined the association between long‐term (~10 years) changes in self‐reported sleep quality and risk of any chronic musculoskeletal pain and chronic widespread pain. The study comprised data on 6,033 people who ...
    • Long‐term efficacy and safety of biosimilar infliximab (CT‐P13) after switching from originator infliximab: Open‐label extension of the NOR‐SWITCH trial 

      Goll, Guro Løvik; Jørgensen, Kristin Kaasen; Sexton, Joseph; Olsen, Inge Christoffer; Bolstad, Nils; Haavardsholm, Espen A.; Lundin, Knut Erik Aslaksen; Tveit, Kåre Steinar; Lorentzen, Merete; Berset, Ingrid Prytz; Fevang, Bjørg-Tilde Svanes; Kalstad, Synnøve; Ryggen, Kristin; Warren, David; Klaasen, Rolf; Asak, Øivind Wessel; Baigh, Somyeh; Blomgren, Ingrid; Brenna, Øystein; Bruun, Trude J; Dvergsnes, Katrine; Frigstad, Svein Oskar; Myrnes, Inger; Hatten, Ingvild Helgheim; Huppertz-Hauss, Gert; Henriksen, Magne; Hoie, Sunniva S.; Krogh, Jan Reidar; Midtgard, Irina P.; Mielnik, Pawel; Moum, Bjørn; Noraberg, Geir; Poyan, Armin; Prestegård, Ulf; Rashid, Haroon Ur; Strand, Eldri Kveine; Skjetne, Kristine; Seeberg, Kathrine; Torp, Roald; Ystrøm, Carl Magnus; Vold, Cecilia; Zettel, Camilla C.; Waksvik, Kenneth; Gulbrandsen, Bjørn; Hagfors, Jon; Mørk, Cato; Jahnsen, Jørgen; Kvien, Tore Kristian (Journal article; Peer reviewed, 2019)
      Background and objectives The 52‐week, randomized, double‐blind, noninferiority, government‐funded NOR‐SWITCH trial demonstrated that switching from infliximab originator to less expensive biosimilar CT‐P13 was not ...
    • Loss of glutamate transporter eaat2a leads to aberrant neuronal excitability, recurrent epileptic seizures, and basal hypoactivity 

      Hotz, Adriana L.; Jamali, Ahmed; Rieser, Nicolas N.; Niklaus, Stephanie; Aydin, Ecem; Myren-Svelstad, Sverre; Lalla, Laetitia Noelle Patricia; Jurisch-Yaksi, Nathalie; Yaksi, Emre; Neuhauss, Stephan C.F. (Peer reviewed; Journal article, 2021)
      Astroglial excitatory amino acid transporter 2 (EAAT2, GLT-1, and SLC1A2) regulates the duration and extent of neuronal excitation by removing glutamate from the synaptic cleft. Hence, an impairment in EAAT2 function could ...