Blar i Fakultet for medisin og helsevitenskap (MH) på tittel
Viser treff 2634-2653 av 14995
-
Current European guidelines for management of arterial hypertension: Are they adequate for use in primary care? Modelling study based on the Norwegian HUNT 2 population
(Journal article; Peer reviewed, 2009)Background: Previous studies indicate that clinical guidelines using combined risk evaluation for cardiovascular diseases (CVD) may overestimate risk. The aim of this study was to model and discuss implementation of the ... -
Current postgraduate training in emergency medicine in the Nordic countries
(Peer reviewed; Journal article, 2023)Background Emergency Medicine (EM) is an independent specialty in all five Nordic countries. This study aims to evaluate the structure of post-graduate EM training in the area. Methods A leading hospital or hospitals ... -
Current vaginal discharge management at a tertiary referral hospital in Nepal, patient reported outcomes
(Master thesis, 2022)Background: Abnormal vaginal discharge is a common medical problem among women of childbearing age, with an estimated 5–10 million clinic visits each year worldwide. (1,2,12) Due to hesitation to undergo vaginal examination ... -
Cut-off evaluation of intrathecal oligoclonal bands of IgM in relapsing-remitting multiple sclerosis; a retrospective study
(Peer reviewed; Journal article, 2022)Background Multiple sclerosis (MS) is the most common demyelinating disease and characterized by immunological changes. Oligoclonal bands of IgG in CSF not seen in corresponding serum have been used for many years as ... -
Cycle acceleration and suicide attempt in patients with bipolar disorder
(Doctoral thesis at NTNU;2015:248, Doctoral thesis, 2015)Sammendrag av avhandlingen: Bipolar lidelse kjennetegnes av både depresjoner og hypomanier eller manier i sykehistorien. Det er ofte uforutsigbart når neste sykdomsepisode kommer. Noen pasienter opplever at de friske ... -
Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
(Journal article; Peer reviewed, 2011)Background Multiple myeloma is an incurable disease requiring the development of effective therapies which can be used clinically. We have elucidated the potential for manipulating the cAMP signaling pathway as a target ... -
Cyclic Arginine–Glycine–Aspartate-Decorated Lipid Nanoparticle Targeting toward Inflammatory Lesions Involves Hitchhiking with Phagocytes
(Peer reviewed; Journal article, 2021)Active-targeting nanomedicine formulations have an intricate in vivo behavior. Nanomedicines developed to target endothelial αvβ3-integrin are recently demonstrated to display extensive uptake by circulating phagocytes. ... -
Cycling at Altitude: Lower Absolute Power Output as the Main Cause of Lower Gross Efficiency
(Peer reviewed; Journal article, 2019)Background: Although cyclists often compete at altitude, the effect of altitude on gross efficiency (GE) remains inconclusive. Purpose: To investigate the effect of altitude on GE at the same relative exercise intensity ... -
A cycling exergaming platform to improve cardiorespiratory fitness and encourage independent exercise behaviour among adults
(Doctoral theses at NTNU;2021:304, Doctoral thesis, 2021) -
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
(Journal article, 2016)Atherosclerosis is an inflammatory disease linked to elevated blood cholesterol concentrations. Despite ongoing advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains the leading cause ... -
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
(Journal article, 2017)Cholesterol crystals (CC) are abundant in atherosclerotic plaques and promote inflammatory responses via the complement system and inflammasome activation. Cyclic oligosaccharide 2-hydroxypropyl-β-cyclodextrin (BCD) is a ... -
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
(Journal article; Peer reviewed, 2017)Cholesterol crystals (CC) are abundant in atherosclerotic plaques and promote inflammatory responses via the complement system and inflammasome activation. Cyclic oligosaccharide 2-hydroxypropyl-β-cyclodextrin (BCD) is a ... -
The Cyclooxygenase 2 inhibitor etoricoxib as adjunctive therapy in tuberculosis impairs macrophage control of mycobacterial growth
(Peer reviewed; Journal article, 2023)Background Current tuberculosis treatment regimens could be improved by adjunct host-directed therapies (HDT) targeting host responses. We investigated the antimycobacterial capacity of macrophages from patients with ... -
CYP2C19 – genvariant CYP2C19*17 og rask omsetting av legemidler
(Master thesis, 2011)Mutasjoner i genene som koder for CYP-enzymene med klinisk betydning, påvirker aktiviteten til enzymet. Doseringen av legemidler må tilpasses for å oppnå den ønskede responsen på legemiddelbehandlingen. Genet CYP2C19 koder ... -
Cytochrome P-450 (CYP) inhibition by commercial Rhodiola rosea products in vitro and in humans
(Doctoral theses at NTNU;2017:244, Doctoral thesis, 2017)Cytokrom P-450 (CYP) inhibering av kommersielle Rhodiola rosea produkter in vitro og i mennesker. Rosenrot (Rhodiola rosea) er et populært naturprodukt med en global utbredelse. Tidligere studier har vist at naturprodukter ... -
Cytokine Network in Scrub Typhus: High Levels of Interleukin-8 Are Associated with Disease Severity and Mortality
(Journal article; Peer reviewed, 2014)Background: Scrub typhus, caused by Orientia tsutsugamushi, is endemic in the Asia-Pacific region. Mortality is high if untreated, and even with treatment as high as 10–20%, further knowledge of the immune response during ... -
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
(Peer reviewed; Journal article, 2023)Background Tocilizumab improves myocardial salvage index (MSI) in patients with ST-elevation myocardial infarction (STEMI), but its mechanisms of action are unclear. Here, we explored how cytokines were affected by tocilizumab ... -
Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond
(Peer reviewed; Journal article, 2021)Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands. We performed cytokine profiling of 1149 longitudinal serum ... -
Cytokine profiles and diagnoses in elderly, hospitalised psychiatric patients
(Journal article; Peer reviewed, 2018)Background There is a paucity of studies on inflammatory markers in elderly psychiatric patients. Hence, our study was undertaken to investigate cytokines as biomarkers in diagnostically unselected elderly patients admitted ... -
Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis
(Journal article; Peer reviewed, 2016)Human metapneumovirus (hMPV) causes severe airway infection in children that may be caused by an unfavorable immune response. The nature of the innate immune response to hMPV in naturally occurring infections in children ...