Blar i Fakultet for medisin og helsevitenskap (MH) på tittel
Viser treff 9728-9747 av 15834
-
Musikkterapiens effekt på livskvalitet hos personer med demens
(Bachelor thesis, 2022)Eldre personer med demens er en økende og sårbar gruppe i samfunnet. Pasientgruppen behøver bistand til å håndtere de utfordringene diagnosen medfører. Vernepleiere kan bidra med en systematisk og planlagt oppfølging, og ... -
Mutasjonstesting ved ikke-småcellet lungekreft
(Peer reviewed; Journal article, 2012)BAKGRUNN. Epidermal vekstfaktor-reseptor (EGFR) tyrosinkinasehemmere (EGFR-TKI) er en relativt ny klasse legemidler til behandling av ikke-småcellet lungekreft. Den nasjonale faggruppen for lungekreft, Norsk Lunge Cancer ... -
Mutation Spectrum in Liquid Versus Solid Biopsies From Patients With Advanced astroenteropancreatic Neuroendocrine Carcinoma
(Peer reviewed; Journal article, 2023)Purpose Gastroenteropancreatic neuroendocrine carcinomas (GEP-NEC) are rare and have a poor prognosis. Most GEP-NEC are diagnosed with metastatic disease, with only minor biopsies available for molecular diagnostics. We ... -
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
(Peer reviewed; Journal article, 2022)Introduction: Multiple myeloma (MM) is a heterogeneous disease where cancer-driver mutations and aberrant signaling may lead to disease progression and drug resistance. Drug responses vary greatly, and there is an unmet ... -
Mutational signature analysis reveals NTHL1 deficiency to cause a multi-tumor phenotype
(Peer reviewed; Journal article, 2019)Biallelic germline mutations affecting NTHL1 predispose carriers to adenomatous polyposis and colorectal cancer, but the complete phenotype is unknown. We describe 29 individuals carrying biallelic germline NTHL1 mutations ... -
Mutations in the substrate binding site of human heat-shock protein 70 indicate specific interaction with HLA-DR outside the peptide binding groove
(Journal article; Peer reviewed, 2014)Heat-shock protein 70 (Hsp70)–peptide complexes are involved in MHC class I- and II-restricted antigen presentation, enabling enhanced activation of T cells. As shown previously, mammalian cytosolic Hsp70 (Hsc70) molecules ... -
MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP
(Journal article; Peer reviewed, 2018)Nucleotides in the free pool are more susceptible to nonenzymatic methylation than those protected in the DNA double helix. Methylated nucleotides like O6-methyl-dGTP can be mutagenic and toxic if incorporated into DNA. ... -
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool
(Peer reviewed; Journal article, 2020)MutT homologue 1 (MTH1) removes oxidized nucleotides from the nucleotide pool and thereby prevents their incorporation into the genome and thereby reduces genotoxicity. We previously reported that MTH1 is an efficient ... -
My Health Sensor, my Classifier – Adapting a Trained Classifier to Unlabeled End-User Data
(Peer reviewed; Journal article, 2022)Sleep apnea is a common yet severely under-diagnosed sleep related disorder. Unattended sleep monitoring at home with low-cost sensors can be leveraged for condition detection, and Machine Learning offers a generalized ... -
My husband is not ill; He has memory loss - Caregivers perspectives on health care services for persons with dementia
(Journal article; Peer reviewed, 2019)Background To explore informal caregivers’ perspectives and perceived needs related to health care services/activities for older adults with dementia, in order to understand barriers and facilitators to participation. The ... -
MYC amplifications in myeloma cell lines; correlation with MYC-inhibitor efficacy
(Journal article; Peer reviewed, 2015)In multiple myeloma, elevated MYC expression is related to disease initiation and progression. We found that in myeloma cell lines, MYC gene amplifications were common and correlated with MYC mRNA and protein. In primary ... -
MYC dysregulation in the progression of multiple myeloma
(Journal article; Peer reviewed, 2019) -
Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition
(Journal article; Peer reviewed, 2014)The type VII secretion systems are conserved across mycobacterial species and in many Gram-positive bacteria. While the well-characterized Esx-1 pathway is required for the virulence of pathogenic mycobacteria and conjugation ... -
Mycobacterium smegmatis Vaccine Vector Elicits CD4+ Th17 and CD8+ Tc17 T Cells With Therapeutic Potential to Infections With Mycobacterium avium
(Peer reviewed; Journal article, 2020)Mycobacterium avium (Mav) complex is increasingly reported to cause non-tuberculous infections in individuals with a compromised immune system. Treatment is complicated and no vaccines are available. Previous studies have ... -
Mycoplasma genitalium and sexual behaviour: A cross-sectional study of students in Trondheim, Norway
(Master thesis, 2016)Background: Screening of Mycoplasma genitalium is not recommended in Norway. Our objective was to investigate the prevalence of M. genitalium and associated sexual habits among students in Trondheim, Norway. Methods: In ... -
Mycoplasma genitalium in the Far North Queensland backpacker population: An observational study of prevalence and azithromycin resistance
(Journal article; Peer reviewed, 2018)Background Mycoplasma genitalium is a sexually transmitted infection (STI), and a common cause of non-gonococcal urethritis (NGU). There is concern regarding the rise in prevalence of M. genitaliumand rates of resistance ... -
Mycoplasma genitalium Macrolide-resistance and treatment options
(Doctoral theses at NTNU;2020:360, Doctoral thesis, 2020) -
Mycotic abdominal aortic aneurysm caused by Borrelia afzelii: a case report
(Peer reviewed; Journal article, 2022)Background Inflammatory aneurysms and mycotic aneurysms make up a minority of abdominal aortic aneurysms. Mainly autoimmune mechanisms are proposed in the pathogenesis of inflammatory aneurysms, and it is not routine ... -
Myeloma-derived extracellular vesicles mediate HGF/c-Met signaling in osteoblast-like cells
(Journal article; Peer reviewed, 2019)Multiple myeloma is an incurable cancer of antibody-producing plasma cells. Hepatocyte growth factor (HGF), a cytokine aberrantly expressed in half of myeloma patients, is involved in myeloma pathogenesis by enhancing ... -
Mykpreservering og klinisk anatomi
(Peer reviewed; Journal article, 2022)Mykpreservering av legemer kan være en stor mulighet i anatomisk videreutdanning av kirurger og andre klinikere. Universitetene kan legge til rette, men hvem tar regningen? De siste årene har anatomiske avdelinger i ...