Browsing Institutt for kjemi by Author "Yu, Qiang"
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Enantioselective Synthesis of Homo-N-Nucleosides Containing a 1,4-Dioxane Sugar Analog
Yu, Qiang; Carlsen, Per Henning (Journal article; Peer reviewed, 2008)A dioxane homo-sugar analog, (2S,5S)-and (2R,5S)-5-[(4S)-2,2-dimethyl-1,3- dioxolan-4-yl]-2-iodomethyl-1,4-dioxane was prepared from (2R,3R)-dimethyl tartrate, and further elaborated into the corresponding homo-N-nucleoside ... -
Synthesis of a Novel Benzoyl Adenosine Analog Containing a 1, 4-Dioxane Sugar Analog and the Synthesis of a Corresponding Uracil Adenine Dinucleotide
Yu, Qiang; Carlsen, Per Henning (Journal article; Peer reviewed, 2011)Adenosine analogs in which the sugar unit was replaced by a 1,4-dioxane sugar equivalent, were prepared by coupling the 1,4-dioxane sugar analog as its anomeric acetates, with N6-benzoyl protected adenine. The 1,4-dioxane ... -
Synthesis of Novel Homo-N-Nucleoside Analogs Composed of a Homo-1,4-Dioxane Sugar Analog and Substituted 1,3,5-Triazine Base Equivalents
Yu, Qiang; Schwidom, Dirk; Exner, Alexander; Carlsen, Per Henning (Journal article; Peer reviewed, 2008)Enantioselective syntheses from dimethyl tartrate of 1,3,5-triazine homo-Nnucleoside analogs, containing a 1,4-dioxane moiety replacing the sugar unit in natural nucleosides, were accomplished. The triazine heterocycle ... -
Synthesis of Optically Active Nucleosides, Nucleotides and Oligonucleatide Analogues
Yu, Qiang (Doktoravhandlinger ved NTNU, 1503-8181; 2008:328, Doctoral thesis, 2008)The main goal of this project was to synthesize various kinds of polynucleotide analogues that contained either 1,3-dioxane or 1,4-dioxane sugar moiety and several optically active nucleoside analogues that containing ... -
Synthesis of polynucleotide analogs containing a polyvinyl alcohol backbone
Yu, Qiang; Carlsen, Per Henning (Journal article; Peer reviewed, 2008)Water soluble homo-base polynucleotide analogues were synthesized in which polyvinyl alcohol and partially phosphonated polyvinyl alcohol constituted the backbones, onto which were grafted uracil or adenine via 1,3-dioxane ...