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Synthetic Efforts to Investigate the Effect of Planarizing the Triarylamine Geometry in Dyes for Dye-Sensitized Solar Cells
(Peer reviewed; Journal article, 2022)The geometry of a dye for dye-sensitized solar cells (DSSCs) has a major impact on its optical and electronic properties. The dye structure also dictates the packing properties and how well the dye insulates the metal–oxide ... -
Synthetic exploration towards total synthesis of Fusolanone B
(Master thesis, 2021)γ-pyronet Fusolanone B (28), tidligere isolert av sopp, har vist potensiale som mulig antibiotika. I dette prosjektet er en retrosyntese inspirert av biosyntese av polyketider blitt utført, og to ulike reaksjonsveier har ... -
Synthetic strategies towards 4,6-disubstituted pyrrolo[2,3-d]pyrimidines as potential CSF-1R inhibitors
(Master thesis, 2019)Målet med denne masteroppgaven var å syntetisere nye 4,6-disubstituerte pyrrolo[2,3-d]pyrimidiner som hemmere for CSF-1R (”colony stimulating factor 1 receptor”) tyrosinkinase. En ny strategi for syntese av disse er også ... -
Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents
(Peer reviewed; Journal article, 2021)Imidazopyridinones and 7-azaoxindoles are two classes of heterocyclic compounds with only limited previous use in organic and medicinal chemistry. Various synthetic methods and routes have been evaluated to identify safe ... -
Synthetic Strategies Towards Substituted Purines and Their CSF1R Activity
(Master thesis, 2018)Overexpression of colony stimulating factor 1 (CF1R) has been implicated in a number of disease states, such as cancer, inflammatory disorders and bone disease. Inhibition of the colony stimulating factor 1 receptor kinase ... -
Synthetic Strategies Towards Substituted Pyrrolopyridines as Possible CSF1R Inhibitors
(Master thesis, 2017) -
Synthetic Studies Toward a chemical library of Piperine analogs
(Master thesis, 2022)Kalium 5-hydroksypenta-2,4-dienalsalt ble fremstilt basert på litteraturprosedyrene. Dette fungerer som det første utgangsmaterialet i fem-karbon homologeringsprosessen og amideringsreaksjonene for å gi henholdsvis dienal- ... -
Synthetic Studies Toward Dysoxylactam A
(Master thesis, 2021)Naturproduktet dysoxylactam A (1) ble isolert fra barken av Dysoxylum Hongkongense i 2019 og ble funnet til å være en potent inhibitor av P-gp i kreftceller. Målet for dette master prosjektet var å utvikle en ny tilnærming ... -
Synthetic Studies toward Gold(I)-catalyzed preparation of Trifluoromethyl Compounds
(Master thesis, 2015)In this project gold(I)-catalyzed reactions on triple bonds has been investigated, with the trifluoromethyl group incorporated. Initially the goal was to develop a new gold(I)-catalyzed trifluoromethylation reaction, as ... -
A systematic non-equilibrium thermodynamics approach for assessing transport mechanisms in membrane distillation
(Peer reviewed; Journal article, 2023)Membrane distillation (MD) is a promising technique for purifying volatile liquids at temperatures below their boiling points. This study presents a systematic non-equilibrium thermodynamics (NET) approach for analysis of ... -
Tailored Porosities of the Cathode Layer for Improved Polymer Electrolyte Fuel Cell Performance
(Journal article; Peer reviewed, 2015)We show experimentally for the fi rst time that the introduction of macro-pores in the nanoporous catalyst layer of a polymer electrolyte membrane fuel cell can improve its performance. We have ach- ieved a Pt utilization ... -
TD-DFT based fine-tuning of molecular excitation energies using evolutionary algorithms
(Journal article; Peer reviewed, 2016)An evolutionary de novo design method is presented to fine-tune the excitation energies of molecules calculated using time-dependent density functional theory (TD-DFT). The approach is applied to a π-conjugated molecular ... -
Teaching complex molecular simulation algorithms: Using self‐evaluation to tailor web‐based exercises at an individual level
(Peer reviewed; Journal article, 2020)It is quite challenging to learn complex mathematical algorithms used in molecular simulations, stressing the importance of using the most advantageous teaching methods. Ideally, individuals should learn at their pace and ... -
Temperature anisotropy at equilibrium reveals nonlocal entropic contributions to interfacial properties
(Journal article, 2018)Density gradient theory for fluids has played a key role in the study of interfacial phenomena for a century. In this work, we revisit its fundamentals by examining the vapor-liquid interface of argon, represented by the ... -
Temporal dynamics of carbon sequestration in coastal North Atlantic fjord system as seen through dissolved organic matter characterisation
(Peer reviewed; Journal article, 2021)Fjord systems in higher latitudes are unique coastal water ecosystems that facilitate the study of dissolved organic matter (DOM) dynamics from surface to deeper waters. The current work was undertaken in the Trondheim ... -
Temporal Trends and Age-Dependent Sex Differences in Chlorinated Paraffin Accumulation in Moose
(Peer reviewed; Journal article, 2022)Previous studies have found relatively high chlorinated paraffin (CP) concentrations in moose (Alces alces) compared with other wildlife from Scandinavia. To explore CP accumulation behaviors in this long-lived terrestrial ... -
Ten-year trends in atmospheric mercury concentrations, meteorological effects and climate variables at Zeppelin, Ny-Ålesund
(Journal article; Peer reviewed, 2013)Results from ten years of gaseous elemental mercury (GEM) measurements at Zeppelin station, Ny-A° lesund, Svalbard, show no overall annual trend between 2000 and 2009. Seasonal trend analysis showed significantly ... -
Ten-year trends of atmospheric mercury in the high Arctic compared to Canadian sub-Arctic and mid-latitude sites
(Journal article; Peer reviewed, 2013)Global emissions of mercury continue to change at the same time as the Arctic is experiencing ongoing climatic changes. Continuous monitoring of atmospheric mercury provides important information about long-term trends in ... -
The anti-cancer potential of sulfoquinovosyl-derivatives from marine sources
(Bachelor thesis, 2020)Cancer is among the deadliest diseases known to man. What makes cancer more challenging to treat than other diseases is the fact that it, by its very nature, undergoes rapid and frequent mutations, making every case – to ... -
The antihypertensive activity of benzimidazoles and the binding of its derivatives to the AT1 receptor
(Bachelor thesis, 2021)For å undersøke den antihypertensive effekten til benzimidazol derivater og effekten av ulike substituenter, på benzimidazol kjernemolekylet, på den antihypertensive effekten vil denne oppgaven se på bindingen av inverse ...