• Effect of acoustic radiation force on displacement of nanoparticles in collagen gels 

      Løvmo, Mia Kvåle; Yemane, Petros Tesfamichael; Bjørkøy, Astrid; Hansen, Rune; Cleveland, Robin O.; Angelsen, Bjørn Atle Johan; Davies, Catharina de Lange (Peer reviewed; Journal article, 2020)
      Penetration of nanoscale therapeutic agents into the extracellular matrix (ECM) of a tumor is a limiting factor for the sufficient delivery of drugs in tumors. Ultrasound (US) in combination with microbubbles causing ...
    • Effect of Acoustic Radiation Force on the Distribution of Nanoparticles in Solid Tumors. 

      Afadzi, Mercy; Myhre, Ola Finneng; Yemane, Petros Tesfamichael; Bjørkøy, Astrid; Torp, Sverre Helge; van Wamel, Annemieke; Lelu, Sylvie; Angelsen, Bjørn Atle Johan; Davies, Catharina de Lange (Peer reviewed; Journal article, 2020)
      Acoustic radiation force (ARF) might improve the distribution of nanoparticles (NPs) in tumors. To study this, tumors growing subcutaneously in mice were exposed to focused ultrasound (FUS) either 15 min or 4 h after the ...
    • Primary Porcine Brain Endothelial Cells as In Vitro Model to Study Effects of Ultrasound and Microbubbles on Blood-Brain Barrier Function 

      Lelu, Sylvie; Afadzi, Mercy; Berg, Sigrid; Åslund, Andreas; Torp, Sverre Helge; Sattler, Wolfgang; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2017)
      Focused ultrasound in the presence of microbubbles transiently and reversibly opens the blood-brain barrier (BBB) in rodents and humans thereby providing a time window for increased drug delivery into brain tissue. To get ...