Blar i Institutt for bioteknologi og matvitenskap på forfatter "Irla, Marta"
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Effect of hydrogen peroxide in the production of L-lysine-derived amino acids in Bacillus methanolicus
Skagestad, Brynjar (Master thesis, 2022)Bacillus methanolicus er en termofil, fakultativ metylotrofisk bakterie som nylig har tiltrukket seg økt interesse for sitt potensiale som en bærekraftig cellefabrikk innenfor industriell bioteknologi. Bakteriens evne til ... -
Genome-based genetic tool development for Bacillus methanolicus: Theta-and rolling circle-replicating plasmids for inducible gene expression and application to methanol-based cadaverine production
Irla, Marta; Heggset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer; Brautaset, Trygve; Wendisch, Volker F. (Peer reviewed; Journal article, 2016)Bacillus methanolicus is a thermophilic methylotroph able to overproduce amino acids from methanol, a substrate not used for human or animal nutrition. Based on our previous RNA-seq analysis a mannitol inducible promoter ... -
L-lysine production by Bacillus methanolicus: Genome-based mutational analysis and L-lysine secretion engineering
Nærdal, Ingemar; Netzer, Roman; Irla, Marta; Krog, Anne; Heggset, Tonje Marita Bjerkan; Wendisch, Volker F.; Brautaset, Trygve (Journal article; Peer reviewed, 2017)Bacillus methanolicus is a methylotrophic bacterium with an increasing interest in academic research and for biotechnological applications. This bacterium was previously applied for methanol-based production of l-glutamate, ... -
Metabolic engineering of Bacillus methanolicus for production of recombinant proteins and acetoin from methanol
Drejer, Eivind Bøe (Doctoral theses at NTNU;2020:339, Doctoral thesis, 2020)The use of methanol as a carbon source for industrial biotechnology is a tantalizing prospect. Methanol is highly abundant, and has a long history of efficient, large-scale production. It can be produced abiotically from ... -
Metabolic Engineering of Bacillus methanolicus MGA3 for Production of Acetoin
Chan, Dennis Tin Chat (Master thesis, 2018)Being a pure, inexpensive, non-food chemical that can be sustainably produced, methanol has attracted great interest as a carbon feedstock for microbial production of commodity/specialty chemicals. In this thesis, ... -
Methanol-based γ-aminobutyric acid (GABA) production by genetically engineered Bacillus methanolicus strains
Irla, Marta; Nærdal, Ingemar; Brautaset, Trygve; Wendisch, Volker F. (Journal article; Peer reviewed, 2017)The use of methanol as a carbon source for biotechnological processes has recently attracted great interest due to relatively low price, high abundance, high purity of methanol, and the fact that it is a non-food raw ... -
Transcriptome analysis of thermophilic methylotrophic Bacillus methanolicus MGA3 using RNA-sequencing provides detailed insights into its previously uncharted transcriptional landscape
Irla, Marta; Neshat, Armin; Brautaset, Trygve; Rückert, Christian; Kalinowski, Jörn; Wendisch, Volker F. (Journal article; Peer reviewed, 2015)Background Bacillus methanolicus MGA3 is a thermophilic, facultative ribulose monophosphate (RuMP) cycle methylotroph. Together with its ability to produce high yields of amino acids, the relevance of this microorganism ...