• Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations 

      Huie, Russel J; Mondello, Stefania; Lindsell, Christopher J.; Antiga, L; Yuh, Esther; Zanier, Elisa; Masson, Serge; Rosario, Bedda; Ferguson, Adam; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Ackerlund, Cecilia; Adams, Hadie; Agnoletti, Vanni; Allanson, Judith; Amrein, Krisztina; Andaluz, Norberto; Azasevac, Antun; Antoni, Anna; Ardon, Hilko; Audibert, Gerard; Auslands, Kaspars; Azouvi, Philippe; Azzolini, Luisa; Baciu, Camelia; Badenes, Rafael; Bartels, Ronald; Barzo, Pal; Bauerfeind, Ursula; Beauvais, Romuald; Beer, Ronny; Belda, Francisco Javier; Bellander, Bo Michael; Belli, Antonio; Bellier, Remy; Benali, Habib; Benard, Thierry; Berardino, Maurizio; Beretta, Luigi; Beynon, Christopher; Bilotta, Federico; Binder, Harald; Biqiri, Erta (Peer reviewed; Journal article, 2020)
      Recent biomarker innovations hold potential for transforming diagnosis, prognostic modeling, and precision therapeutic targeting of traumatic brain injury (TBI). However, many biomarkers, including brain imaging, genomics, ...
    • Blood biomarkers on admission in acute traumatic brain injury: Relations to severity, CT findings and care path in the CENTER-TBI study 

      Czeiter, Endre; Amrein, Krisztina; Gravesteijn, BY; Lecky, Fiona; Menon, David K; Mondello, Stefania; Newcombe, Virginia F; Richter, Sophie; Steyerberg, Ewout W; Vande Vyvere, Thijs; Verheyden, Jan; Xu, Haiyan; Yang, Zhihui; Maas, Andrew I.R.; Wang, Kevin KW; Buki, Andras; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa (Peer reviewed; Journal article, 2020)
      Background: Serum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed to correlate serum biomarkers with clinical severity, care path and imaging abnormalities in TBI, and explore their incremental ...
    • Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study 

      van Veen, Ernest; Van Der Jagt, Mathieu; Cnossen, Maryse C.; Maas, Andrew I. R.; De Beaufort, Inez D.; Menon, David K.; Citerio, Giuseppe; Stocchetti, Nino; Rietdijk, Wim J. R.; van Dijck, Jeroen T. J. M.; Kompanje, Erwin J. O.; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Peer reviewed, 2018)
      Background We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation. Methods Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in ...
    • Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study. 

      Steyerberg, Ewout W; Wiegers, E; Sewalt, C.; Buki, Andras; Citerio, Giuseppe; De Keyser, Veronique; Ercole, Ari; Kunzmann, K.R.; Lanyon, Linda; Lecky, Fiona; Lingsma, Hester F; Manley, Geoffrey T; Nelson, D; Peul, Wilco; Stocchetti, Nino; von Steinbüchel, Nicole; Vande Vyvere, Thijs; Verheyden, Jan; Wilson, Lindsay; Maas, AIR; Menon, David; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røise, Olav; Skandsen, Toril; Røe, Cecilie (Peer reviewed; Journal article, 2019)
      BACKGROUND: The burden of traumatic brain injury (TBI) poses a large public health and societal problem, but the characteristics of patients and their care pathways in Europe are poorly understood. We aimed to characterise ...
    • Change in Headache Suffering and Predictors of Headache after Mild Traumatic Brain Injury: A Population-Based, Controlled, Longitudinal Study with Twelve-Month Follow-Up 

      Nordhaug, Lena Hoem; Linde, Mattias; Follestad, Turid; skandsen, øystein njølstad; Bjarkø, Vera Vik; Skandsen, Toril; Vik, Anne (Journal article; Peer reviewed, 2019)
      Headache attributed to traumatic injury to the head (HAIH) is claimed to be the most common sequela following mild traumatic brain injury (MTBI), but epidemiological evidence is scarce. We explored whether patients with ...
    • Change in Self-Reported Cognitive Symptoms After Mild Traumatic Brain Injury Is Associated With Changes in Emotional and Somatic Symptoms and Not Changes in Cognitive Performance 

      Stenberg, Jonas; Karr, Justin E.; Terry, Douglas P.; Håberg, Asta; Vik, Anne; Skandsen, Toril; Iverson, Grant L. (Peer reviewed; Journal article, 2020)
      Objective: To investigate (a) whether self-reported cognitive symptoms after mild traumatic brain injury (MTBI) are associated with cognitive test performances, and (b) whether improvement in self-reported symptoms from 2 ...
    • Changing care pathways and between-center practice variations in intensive care for traumatic brain injury across Europe: a CENTER-TBI analysis 

      Huijbers, Jilske; Wiegers, E; Lingsma, Hester F; Citerio, Giuseppe; Maas, Andrew I.R.; Menon, David K; Ercole, Ari; Nelson, David; van der Jagt, Mathieu; Steyerberg, Ewout; Helbok, Raimund; Lecky, Fiona; Peul, Wilco; Birg, Tatiana; Zoerle, Tomaso; Carbonara, Marco; Stocchetti, Nino; Andelic, Nada; Andreassen, Lasse; Lund, Stine Borgen; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Sandrød, Oddrun; Schirmer-Mikalsen, Kari; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Brorsson, Camilla; Azzolini, Maria Luisa; Bartels, Ronald; Beer, Ronny; Bellander, Bo-Michael; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Beqiri, Erta; Blaabjerg, Morten; Buki, Andras; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emaliana; Calvi, Maria Rosa; Cameron, Peter; Guillermo, Carbayo Lozano; Sundström, Nina; Tibboel, Dick; Ples, Horia; Sakowitz, Oliver; Ziverte, Agate (Peer reviewed; Journal article, 2020)
      Purpose: To describe ICU stay, selected management aspects, and outcome of Intensive Care Unit (ICU) patients with traumatic brain injury (TBI) in Europe, and to quantify variation across centers. Methods: This is a ...
    • Cognitive Reserve Moderates Cognitive Outcome After Mild Traumatic Brain Injury 

      Stenberg, Jonas; Håberg, Asta; Follestad, Turid; Olsen, Alexander; Iverson, Grant L.; Terry P., Douglas; Karlsen, Rune Hatlestad; Saksvik, Simen Berg; Karaliute, Migle; Ek, John Andre Nebb; Skandsen, Toril; Vik, Anne (Journal article; Peer reviewed, 2019)
      Objective To investigate whether cognitive reserve moderates differences in cognitive functioning between patients with mild traumatic brain injury (MTBI) and controls without MTBI and to examine whether patients with ...
    • Cognitive Reserve Moderates Cognitive Outcome After Mild Traumatic Brain Injury 

      Stenberg, Jonas; Håberg, Asta; Follestad, Turid; Olsen, Alexander; Iverson, Grant L.; Terry P., Douglas; Karlsen, Rune Hatlestad; Saksvik, Simen Berg; Karaliute, Migle; Ek, John Andre Nebb; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2019)
      Objective To investigate whether cognitive reserve moderates differences in cognitive functioning between patients with mild traumatic brain injury (MTBI) and controls without MTBI and to examine whether patients with ...
    • Developing Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery 

      Stenberg, Jonas; Karr, Justin E.; Terry, Douglas P.; Saksvik, Simen Berg; Vik, Anne; Skandsen, Toril; Silverberg, Noah D.; Iverson, Grant L. (Peer reviewed; Journal article, 2020)
      Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores ...
    • Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury 

      Mikolic, Ana; van Klaveren, David; Oude Groeniger, Joost; Wiegers, E; Lingsma, Hester F; Zeldovich, Marina; von Steinbüchel, Nicole; Maas, Andrew I.R.; Roeters van Lennep, Jeanine; Polinder, Suzanne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina (Peer reviewed; Journal article, 2020)
      Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, ...
    • Diffusion kurtosis imaging in mild traumatic brain injury and postconcussional syndrome 

      Karlsen, Rune Hatlestad; Einarsen, Cathrine Elisabeth; Moe, Hans Kristian; Håberg, Asta; Vik, Anne; Skandsen, Toril; Eikenes, Live (Journal article; Peer reviewed, 2019)
      ims of this study were to investigate white matter (WM) and thalamus microstructure 72 hr and 3 months after mild traumatic brain injury (TBI) with diffusion kurtosis imaging (DKI) and diffusion tensor imaging (DTI), and ...
    • Effects of alcohol on Glasgow Coma Scale score and outcome in patients with moderate and severe traumatic brain injury 

      Rundhaug, Nils Petter (Master thesis, 2013)
      Introduction/object: Alcohol is among many clinicians assumed to be a confounding factor when evaluating the consciousness of traumatic brain injury (TBI) patients. Research findings are divergent, and the aim of this study ...
    • End-of-life practices in traumatic brain injury patients: Report of a questionnaire from the CENTER-TBI study 

      van Veen, Ernest; van der Jagt, Mathieu; Citerio, Guiseppe; Stocchetti, Nino; Epker, Jelle; Gommers, Diederik; Burdorf, Lex; Menon, David K; Maas, Andrew I.R.; Lingsma, Hester F; Kompanje, Erwin J.O.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco (Peer reviewed; Journal article, 2020)
      Purpose We aimed to study variation regarding specific end-of-life (EoL) practices in the intensive care unit (ICU) in traumatic brain injury (TBI) patients. Materials and methods Respondents from 67 hospitals ...
    • Epidemiology of physical trauma at Dhulikhel hospital in Nepal - a 10 week survey 

      Tyridal, Ingrid (Master thesis, 2013)
      Background: Dhulikhel Hospital (DH) is a Nepalese community hospital serving approximately 1 million people in the district of Kavre and its neighbouring areas. DH also provides services to outreach centres all over Nepal. ...
    • Evaluation of the Scandinavian guidelines for head injuries based on a consecutive series with computed tomography from a Norwegian university hospital 

      Strand, Ingrid H.; Solheim, Ole; Moen, Kent Gøran; Vik, Anne (Journal article; Peer reviewed, 2012)
      Background: This study prospectively assesses clinical characteristics and management of consecutive minimal, mild and moderate head injury patients referred for CT scans. Compliance with the Scandinavian head injury guidelines ...
    • Frequency and prognostic factors of olfactory dysfunction after traumatic brain injury 

      Bratt, Mette; Skandsen, Toril; Hummel, Thomas; Moen, Kent Gøran; Vik, Anne; Nordgård, Ståle; Helvik, Anne-Sofie (Journal article; Peer reviewed, 2018)
      Objective: To assess the frequency and factors associated with posttraumatic olfactory dysfunction, including anosmia, in a follow-up of patients with moderate and severe traumatic brain injury (TBI). Methods: The setting ...
    • Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study 

      Andelic, Nada; Røe, Cecilie; Brunborg, Cathrine; Zeldovich, Marina; Løvstad, Marianne; Løke, Daniel; Borgen, Ida Maria Henriksen; Voormolen, Daphne; Howe, Emilie; Forslund, Marit Vindal; DAHL, HILDE MARGRETE; von Steinbuechel, Nicole; Helseth, Eirik; Røise, Olav; Frisvold, Shirin; Anke, Audny; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background Fatigue is one of the most commonly reported subjective symptoms following traumatic brain injury (TBI). The aims were to assess frequency of fatigue over the first 6 months after TBI, and examine whether fatigue ...
    • Global Characterisation of Coagulopathy in Isolated Traumatic Brain Injury (iTBI): A CENTER-TBI Analysis 

      Böhm, JK; Güting, Helge; Thorn, S; Schäfer, Nadine; Rambach, V; Schöchl, Herbert; Grottke, Oliver; Rossaint, Rolf; Stanworth, Simon; Curry, Nicola; Lefering, Rolf; Maegele, Marc; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is associated with high rates of complications, unfavourable outcomes and mortality. The mechanism of the development of TBI-associated ...
    • Headache Attributed to Traumatic Injury to the Head: Epidemiological Evidence and Natural Course 

      Nordhaug, Lena Hoem (Doctoral theses at NTNU;2019:58, Doctoral thesis, 2019)