Browsing NTNU Open by Author "Partali, Vassilia"
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Cationic polyene phospholipids as DNA carriers for ocular gene therapy
Machado, Susana; Calado, Sofia; Bitoque, Diogo; Oliveira, Ana Vanessa; Øpstad, Christer Lorentz; Zeeshan, Muhammad; Sliwka, Hans-Richard; Partali, Vassilia; Pungente, Michael; Silva, Gabriela (Journal article; Peer reviewed, 2014)Recent success in the treatment of congenital blindness demonstrates the potential of ocular gene therapy as a therapeutic approach. The eye is a good target due to its small size, minimal diffusion of therapeutic agent ... -
Key to xenobiotic carotenoids
Sliwka, Hans-Richard; Partali, Vassilia (Journal article; Peer reviewed, 2012)A listing of carotenoids with heteroatoms (X = F, Cl, Br, I, Si, N, S, Se, Fe) directly attached to the carotenoid carbon skeleton has been compiled. The 178 listed carotenoids with C,H,X atoms demonstrate that the ... -
Novel cationic carotenoid lipids as delivery vectors of antisense oligonucleotides for exon skipping in duchenne muscular dystrophy
Popplewell, Linda; Abu-Dayya, Aseel; Khanna, Tushar; Flinterman, Marcella; Abdul Khalique, nada; Raju, Liji; Øpstad, Christer Lorentz; Sliwka, Hans-Richard; Partali, Vassilia; Dickson, George; Pungente, Michael (Journal article; Peer reviewed, 2012)Duchenne Muscular Dystrophy (DMD) is a common, inherited, incurable, fatal muscle wasting disease caused by deletions that disrupt the reading frame of the DMD gene such that no functional dystrophin protein is produced. ... -
Syntese av crocin-derivater
Bjørk, Tina Beate (Master thesis, 2008)Syntese av crocinderivater. Syntese av crocetin, både kjemisk og ved hjelp av mikroorganisme. -
Syntese av crocin-derivater
Bjørk, Tina Beate (Master thesis, 2008)Syntese av crocinderivater. Syntese av crocetin, både kjemisk og ved hjelp av mikroorganisme. -
Syntheses and properties of long chain polyenes - Syntheses and properties of cationic and anionic polyene lipids
Zeeshan, Muhammad (Doctoral Theses at NTNU, 1503-8181; 2012-271, Doctoral thesis, 2012) -
Synthesis and preliminary investigations of the siRNA delivery potential of novel, single-chain rigid cationic carotenoid lipids
Pungente, Michael; Jubeli, Emile; Øpstad, Christer Lorentz; Al-Kawaz, Mais; Barakat, Nour; Ibrahim, Tarek; Abdul Khalique, Nada; Raju, Liji; Jones, Rachel; Leopold, Philip; Sliwka, Hans-Richard; Partali, Vassilia (Journal article; Peer reviewed, 2012)The success of nucleic acid delivery requires the development of safe and efficient delivery vectors that overcome cellular barriers for effective transport. Herein we describe the synthesis of a series of novel, ... -
Synthesis of a Novel Tocopherol/Carotenoid Derivative
Haugland, Marius Myreng (Master thesis, 2012)The goal of this work is the synthesis of a tocopherol/carotenoid hybridderivative (1, figure II). The novel derivative is believed to exhibitsynergistic antioxidant effects between its chromanol and polyene consituents.The ... -
Synthesis of a Precursor for a Carotenoid Cationic Lipid
Vo, Mong Truc (Master thesis, 2012)The goal of this work was the synthesis of a carotenoid cationic lipid for the research of carriers of nucleic acids into defective cells via transfection therapy. In the course of this project a precursor for the carotenoid ... -
Synthesis of conjugated unsaturated Amino Acids
Buvik, Vanja (Master thesis, 2016)Of the three main groups of biomolecules - lipids, carbohydrates and proteins - lipids and carbohydrates containing polyene functionalities have already been investigated. This thesis describes a first approach to the ...