• Cationic polyene phospholipids as DNA carriers for ocular gene therapy 

      Machado, Susana; Calado, Sofia; Bitoque, Diogo; Oliveira, Ana Vanessa; Øpstad, Christer Lorentz; Zeeshan, Muhammad; Sliwka, Hans-Richard; Partali, Vassilia; Pungente, Michael; Silva, Gabriela (Journal article; Peer reviewed, 2014)
      Recent success in the treatment of congenital blindness demonstrates the potential of ocular gene therapy as a therapeutic approach. The eye is a good target due to its small size, minimal diffusion of therapeutic agent ...
    • Key to xenobiotic carotenoids 

      Sliwka, Hans-Richard; Partali, Vassilia (Journal article; Peer reviewed, 2012)
      A listing of carotenoids with heteroatoms (X = F, Cl, Br, I, Si, N, S, Se, Fe) directly attached to the carotenoid carbon skeleton has been compiled. The 178 listed carotenoids with C,H,X atoms demonstrate that the ...
    • Novel cationic carotenoid lipids as delivery vectors of antisense oligonucleotides for exon skipping in duchenne muscular dystrophy 

      Popplewell, Linda; Abu-Dayya, Aseel; Khanna, Tushar; Flinterman, Marcella; Abdul Khalique, nada; Raju, Liji; Øpstad, Christer Lorentz; Sliwka, Hans-Richard; Partali, Vassilia; Dickson, George; Pungente, Michael (Journal article; Peer reviewed, 2012)
      Duchenne Muscular Dystrophy (DMD) is a common, inherited, incurable, fatal muscle wasting disease caused by deletions that disrupt the reading frame of the DMD gene such that no functional dystrophin protein is produced. ...
    • Syntese av crocin-derivater 

      Bjørk, Tina Beate (Master thesis, 2008)
      Syntese av crocinderivater. Syntese av crocetin, både kjemisk og ved hjelp av mikroorganisme.
    • Syntese av crocin-derivater 

      Bjørk, Tina Beate (Master thesis, 2008)
      Syntese av crocinderivater. Syntese av crocetin, både kjemisk og ved hjelp av mikroorganisme.
    • Syntheses and properties of long chain polyenes - Syntheses and properties of cationic and anionic polyene lipids 

      Zeeshan, Muhammad (Doctoral Theses at NTNU, 1503-8181; 2012-271, Doctoral thesis, 2012)
    • Synthesis and preliminary investigations of the siRNA delivery potential of novel, single-chain rigid cationic carotenoid lipids 

      Pungente, Michael; Jubeli, Emile; Øpstad, Christer Lorentz; Al-Kawaz, Mais; Barakat, Nour; Ibrahim, Tarek; Abdul Khalique, Nada; Raju, Liji; Jones, Rachel; Leopold, Philip; Sliwka, Hans-Richard; Partali, Vassilia (Journal article; Peer reviewed, 2012)
      The success of nucleic acid delivery requires the development of safe and efficient delivery vectors that overcome cellular barriers for effective transport. Herein we describe the synthesis of a series of novel, ...
    • Synthesis of a Novel Tocopherol/Carotenoid Derivative 

      Haugland, Marius Myreng (Master thesis, 2012)
      The goal of this work is the synthesis of a tocopherol/carotenoid hybridderivative (1, figure II). The novel derivative is believed to exhibitsynergistic antioxidant effects between its chromanol and polyene consituents.The ...
    • Synthesis of a Precursor for a Carotenoid Cationic Lipid 

      Vo, Mong Truc (Master thesis, 2012)
      The goal of this work was the synthesis of a carotenoid cationic lipid for the research of carriers of nucleic acids into defective cells via transfection therapy. In the course of this project a precursor for the carotenoid ...
    • Synthesis of conjugated unsaturated Amino Acids 

      Buvik, Vanja (Master thesis, 2016)
      Of the three main groups of biomolecules - lipids, carbohydrates and proteins - lipids and carbohydrates containing polyene functionalities have already been investigated. This thesis describes a first approach to the ...