Browsing NTNU Open by Author "Jakola, Asgeir Store"
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Are there predilection sites for intracranial meningioma? A population-based atlas
Hosainey, Sayied Abdol Mohieb; Bouget, David; Reinertsen, Ingerid; Sagberg, Lisa Millgård; Torp, Sverre Helge; Jakola, Asgeir Store; Solheim, Ole (Peer reviewed; Journal article, 2021)Meningioma is the most common benign intracranial tumor and is believed to arise from arachnoid cap cells of arachnoid granulations. We sought to develop a population-based atlas from pre-treatment MRIs to explore the ... -
Brain atlas for assessing the impact of tumor location on perioperative quality of life in patients with high-grade glioma: A prospective population-based cohort study
Sagberg, Lisa Millgård; Iversen, Daniel Høyer; Fyllingen, Even Hovig; Jakola, Asgeir Store; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2019)Background Tumor location is important for surgical decision making. Particular attention is paid to regions that contain sensorimotor and language functions, but it is unknown if these are the most important regions from ... -
Clinical Course in Chronic Subdural Hematoma Patients Aged 18–49 Compared to Patients 50 Years and Above: A Multicenter Study and Meta-Analysis
Bartek, Jiri; Sjåvik, Kristin; Dhawan, Sanjay; Sagberg, Lisa Millgård; Kristiansson, Helena; Ståhl, Fredrik; Förander, Petter; Chen, Clark C.; Jakola, Asgeir Store (Journal article; Peer reviewed, 2019)Objective: Chronic Subdural Hematoma (cSDH) is primarily a disease of elderly, and is rare in patients <50 years, and this may in part be related to the increased brain atrophy from 50 years of age. This fact may also ... -
Comparative effectiveness of microdecompression and laminectomy for central lumbar spinal stenosis: Study protocol for an observational study
Nerland, Ulf Skule; Jakola, Asgeir Store; Solheim, Ole; Weber, Clemens; Rao, Vidar; Lønne, Greger; Solberg, Tore; Salvesen, Øyvind; Carlsen, Sven Magnus; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Peer reviewed, 2014)Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal ... -
Depression and ability to work after vestibular schwannoma surgery: a nationwide registry-based matched cohort study on antidepressants, sedatives, and sick leave
Thurin, Erik; Förander, Petter; bartek, Jiri Jr.; Gulati, Sasha; Rydén, Isabelle; Smits, Anja; Hesselager, Göran; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)Background In patients with vestibular schwannomas (VS), tumor control is often achieved, and life expectancy is relatively good. The main risks of surgical treatment are hearing loss and facial nerve function. The occurrence ... -
Determinants for Effective ALECSAT Immunotherapy Treatment on Autologous Patient-Derived Glioblastoma Stem Cells
Wenger, Anna; Werlenius, Katja; Hallner, Alexander; Fredrik Bergh, Thoren; Farahmand, Dan; Tisell, Magnus; Smits, Anja; Rydenhag, Bertil; Jakola, Asgeir Store; Caren, Helena (Peer reviewed; Journal article, 2018)Glioblastoma (GBM) is the most aggressive primary brain tumor with a median survival of less than 15 months, emphasizing the need for better treatments. Immunotherapy as a treatment for improving or aiding the patient’s ... -
Development and external validation of a clinical prediction model for functional impairment after intracranial tumor surgery
Staartjes, Victor E.; Broggi, Morgan; Zattra, Costanza Maria; Vasella, Flavio; Velz, Julia; Schiavolin, Silvia; Serra, Carlo; Bartek, Jiri; Fletcher-Sandersjöö, Alexander; Förander, Petter; Kalasauskas, Darius; Renovanz, Mirjam; Ringel, Florian; Brawanski, Konstantin R.; Kerschbaumer, Johannes; Freyschlag, Christian F.; Jakola, Asgeir Store; Sjåvik, Kristin; Solheim, Ole; Schatlo, Bawarjan; Sachkova, Alexandra; Bock, Hans Christoph; Hussein, Abdelhalim; Rohde, Veit; Broekman, Marike L.D.; Nogarede, Claudine O.; Lemmens, Cynthia M.C.; Kernbach, Julius M.; Neuloh, Georg; Bozinov, Oliver; Krayenbühl, Niklaus; Sarnthein, Johannes; Ferroli, Paolo; Regli, Luca; Stienen, Martin N. (Peer reviewed; Journal article, 2021)OBJECTIVE Decision-making for intracranial tumor surgery requires balancing the oncological benefit against the risk for resection-related impairment. Risk estimates are commonly based on subjective experience and generalized ... -
DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomas
Ferreyra Vega, Sandra; Olsson Bontell, Thomas; Corell, Alba; Smits, Anja; Jakola, Asgeir Store; Carén, Helena (Peer reviewed; Journal article, 2021)Background - DNA methylation profiling has facilitated and improved the classification of a wide variety of tumors of the central nervous system. In this study, we investigated the potential utility of DNA methylation ... -
Does risk of brain cancer increase with intracranial volume? A population-based case control study
Fyllingen, Even Hovig; Hansen, Tor Ivar; Jakola, Asgeir Store; Håberg, Asta; Salvesen, Øyvind; Solheim, Ole (Journal article; Peer reviewed, 2018)Background Glioma is the most common primary brain tumor and is believed to arise from glial stem cells. Despite large efforts, there are limited established risk factors. It has been suggested that tissue with more ... -
Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients with Recurrent Glioblastoma: A Randomized Clinical Trial
Werlenius, Katja; Kinhult, Sara; Solheim, Tora S; Magelssen, Henriette; Löfgren, David; Mudaisi, Munila; Hylin, Sofia; Bartek, Jiri; Strandéus, Michael; Lindskog, Magnus; Rashid, Havyan Bahroz; Carstam, Louise; Gulati, Sasha; Solheim, Ole Skeidsvoll; Salvesen, Øyvind Olav; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)Importance Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. Objective To evaluate the efficacy and safety of ... -
Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial
Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger; Vangen-Lønne, Vetle; Taraldsen, Kristin; Tronvik, Erling Andreas; Øie, Lise Rystad; Gulati, Agnete Malm; Sagberg, Lisa Millgård; Jakola, Asgeir Store; Solberg, Tore; Nygaard, Øystein Petter; Salvesen, Øyvind; Gulati, Sasha (Peer reviewed; Journal article, 2022)Importance: The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence of its efficacy is lacking. Objective: To investigate the efficacy of spinal cord burst ... -
Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study
Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders; Padayachy, Llewellyn; Jensberg, Heidi; Dodick, David W.; Salvesen, Øyvind; Gulati, Sasha (Journal article; Peer reviewed, 2018)Background Accurate and reliable clinical and radiological predictors of intracerebral hemorrhage (ICH) outcomes are needed to optimize treatment of ICH. The aim of this study was to investigate functional outcome and ... -
Impact of meningioma surgery on use of antiepileptic, antidepressant, and sedative drugs: A Swedish nationwide matched cohort study
Thurin, Erik; Rydén, Isabelle; Skoglund, Thomas; Smits, Anja; Gulati, Sasha; Hesselager, Göran; Bartek, Jiri Jr.; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)Background: Meningioma is the most common primary intracranial tumor and surgery is the main treatment modality. As death from lack of tumor control is rare, other outcome measures like anxiety, depression and post-operative ... -
Investigating survival, quality of life and cognition in PROton versus photon therapy for IDH- mutated diffuse grade 2 and 3 GLIOmas (PRO-GLIO): a randomised controlled trial in Norway and Sweden
Heggebø, Liv Cathrine; Borgen, Ida Maria Henriksen; Rylander, Hillevi; Kiserud, Cecilie E.; Nordenmark, Tonje Kristin Haug; Hellebust, Taran Annette Paulsen; Evensen, Morten Egeberg; Gustavsson, Magnus; Ramberg, Christina; Sprauten, Mette; Magelssen, Henriette; Blakstad, Hanne; Moorthy, Janani; Andersson, Karin; Raunert, Ingela; Henry, Thomas; Moe, Cecilie; Granlund, Carin; Goplen, Dorota; Brekke, Jorunn; Johannessen, Tor-Christian Aase; Solheim, Tora S; Marienhagen, Kirsten; Humberset, Øyvind; Bergström, Per; Agrup, Måns; Dahl, Ludvig; Gubanski, Michael; Gojon, Helene; Brahme, Carl-Johan; Rydén, Isabelle; Jakola, Asgeir Store; Vik-Mo, Einar O.; Lie, Hanne Cathrine; Asphaug, Lars; Hervani, Maziar; Kristensen, Ingrid; Rüegg, Corina Silvia; Olsen, Inge Christoffer; Ledal, Rolf J; Degsell, Eskil; Werlenius, Katja; Blomstrand, Malin; Brandal, Petter (Peer reviewed; Journal article, 2023)Abstract Introduction The use of proton therapy increases globally despite a lack of randomised controlled trials demonstrating its efficacy and safety. Proton therapy enables sparing of non-neoplastic tissue from ... -
Is intracranial volume a risk factor for IDH-mutant low-grade glioma? A case-control study
Sagberg, Lisa Millgård; Fyllingen, Even Hovig; Hansen, Tor Ivar; Strand, Per Sveino; Håvik, Aril Løge; Sundstrøm, Terje; Corell, Alba; Jakola, Asgeir Store; Salvesen, Øyvind; Solheim, Ole (Peer reviewed; Journal article, 2022)Purpose Risk of cancer has been associated with body or organ size in several studies. We sought to investigate the relationship between intracranial volume (ICV) (as a proxy for lifetime maximum brain size) and risk of ... -
Neurosurgical treatment and outcome patterns of meningioma in Sweden: a nationwide registry-based study
Corell, Alba; Thurin, Erik; Skoglund, Thomas; Farahmand, Dan; Henriksson, Roger; Rydenhag, Bertil; Gulati, Sasha; Bártek, Jiří; Jakola, Asgeir Store (Peer reviewed; Journal article, 2019)Background Surgery is the main treatment modality for intracranial meningiomas, but data on short-term surgical outcome are limited. The aim of this Swedish nationwide registry-based study was to benchmark the 30-day ... -
Prognostic markers for survival in patients with oligodendroglial tumors; a single-institution review of 214 cases
Zetterling, Maria; Berhane, Luwane; Alafuzoff, Irina; Jakola, Asgeir Store; Smits, Anja (Peer reviewed; Journal article, 2017)Background: In the 2016 WHO classification, the diagnosis of oligodendroglioma has been restricted to IDH mutated, 1p19q codeleted tumors (IDHmut-codel). IDHmut oligoastrocytoma is now classified either as oligodendroglioma ... -
Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study
Rydén, Isabelle; Thurin, Erik; Carstam, Louise; Smits, Anja; Gulati, Sasha; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Journal article; Peer reviewed, 2021)Background: Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease. While epilepsy is well-described in patients ... -
Quantitative texture analysis in the prediction of IDH status in low-grade gliomas
Jakola, Asgeir Store; Zang, YH; Skjulsvik, Anne Jarstein; Solheim, Ole; Bø, Hans Kristian; Berntsen, Erik Magnus; Reinertsen, Ingerid; Gulati, Sasha; Förander, Petter; Brismar, Torkel B. (Journal article; Peer reviewed, 2017)Objectives Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of ... -
Return to work following meningioma surgery: a Swedish nationwide registry-based matched cohort study
Thurin, Erik; Corell, Alba; Gulati, Sasha; Smits, Anja; Henriksson, Roger; Bartek, Jiri Jr.; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2020)Background Meningioma is the most common primary intracranial tumor. It is usually slow growing and benign, and surgery is the main treatment modality. There are limited data on return to work following meningioma ...