Browsing NTNU Open by Journals "mAbs"
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NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies.
(Journal article; Peer reviewed, 2020)The mechanism of action of recombinant IgG2/4 antibodies involves blocking of their target without the induction of effector functions. Examples are eculizumab (Soliris®), which is used clinically to block complement factor ...