Blar i NTNU Open på forfatter "Arum, Carl-Jørgen"
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A Study of Urothelial Carcinoma: Gene Expression Profiling, Tumorigenesis and Therapies in Orthotopic Animal Models
Arum, Carl-Jørgen (Doktoravhandlinger ved NTNU, 1503-8181; 2011:27, Doctoral thesis, 2011)En studie om urothelial karsinom: Genekspresjonsprofilering, tumorutvikling og terapi i ortotopiskiske dyremodeller. Urinblærekreft er en hyppig forekommende kreftform som i noen tilfeller har dårlig prognose. Dette arbeide ... -
Analysis of perioperative, postoperative and oncological results after open or robot assisted laparoscopic cystectomy for surgical treatment of bladder cancer
Frøystad, Svenn Joar; Brandal, Anders Egge (Master thesis, 2020)Bakgrunn: Radikal cystektomi er gullstandard for behandling av invasiv blærekreft, men er assosiert med en høy risiko for komplikasjoner med varierende alvorlighetsgrad. Robot Assistert Radikal Cystektomi (RARC) ble innført ... -
Analysis of the movements of kidney stones - Analysis of the movements of kidney stones with the help of 4D ultrasound. A cooperation project between the institute of technical cybernetics at NTNU, clinic of image diagnostics and urologic department at St. Olav’s hospital.
Kragset, Oda (Master thesis, 2015)Objective: The main purpose of this pilot study was to gather information on the movements of kidney stones in a 4 dimensional (4D) perspective through a respiratory cycle, making time the first dimension and space the ... -
Bladder cancer from bench to bedside: Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Blindheim, Augun Jodis (Doctoral theses at NTNU;2021:72, Doctoral thesis, 2021) -
Can a Dinosaur Think? Implementation of Artificial Intelligence in Extracorporeal Shock Wave Lithotripsy
Muller, Sebastien; Abildsnes, Håkon; Østvik, Andreas; Kragset, Oda; Gangås, Inger Sofie Hovd; Birke, Harriet; Langø, Thomas; Arum, Carl-Jørgen (Peer reviewed; Journal article, 2021)Background: Extracorporeal shock wave lithotripsy (ESWL) of kidney stones is losing ground to more expensive and invasive endoscopic treatments. Objective: This proof-of-concept project was initiated to develop artificial ... -
Differentially expressed extracellular vesicle-contained micrornas before and after transurethral resection of bladder tumors
Strømme, Olaf; Heck, Kathleen; Brede, Gaute; Lindholm, Håvard Takle; Otterlei, Marit; Arum, Carl-Jørgen (Peer reviewed; Journal article, 2021)Bladder cancer (BC) is currently diagnosed and monitored by cystoscopy, a costly and invasive procedure. Potential biomarkers in urine, blood, and, more recently, extracellular vesicles (EVs), have been explored as ... -
En bloc radical cystectomy: An overview of the technique and oncological results
Kjøbli, Eirik; Salvesen, Øyvind Olav; Langørgen, Sverre; Størkersen, Øystein; Wibe, Arne; Arum, Carl-Jørgen (Journal article; Peer reviewed, 2022)Objectives To reduce recurrence after radical cystectomy (RC), we developed a technique based on the principles of the circumferential resection margin used during total mesorectal excision for rectal cancer, namely, en ... -
Increased Anticancer Efficacy of Intravesical Mitomycin C Therapy when combined with a PCNA Targeting Peptide
Gederaas, Odrun Arna; Søgaard, Caroline Danielsen; Viset, Trond; Bachke, Siri; Bruheim, Per; Arum, Carl-Jørgen; Otterlei, Marit (Journal article; Peer reviewed, 2014)Non–muscle-invasive bladder cancers (NMIBCs) are tumors confined to the mucosa or the mucosa/submucosa. An important challenge in treatment of NMIBC is both high recurrence and high progression rates. Consequently, more ... -
Myeloma-derived extracellular vesicles mediate HGF/c-Met signaling in osteoblast-like cells
Strømme, Olaf; Psonka Antonczyk, Katarzyna Maria; Stokke, Bjørn Torger; Sundan, Anders; Arum, Carl-Jørgen; Brede, Gaute (Journal article; Peer reviewed, 2019)Multiple myeloma is an incurable cancer of antibody-producing plasma cells. Hepatocyte growth factor (HGF), a cytokine aberrantly expressed in half of myeloma patients, is involved in myeloma pathogenesis by enhancing ... -
T1 bladder cancer in Norway: treatment and survival
Blindheim, Augun Jodis; Fosså, Sophie Dorothea; Babigumira, Ronnie; Myklebust, Tor Åge; Haug, Erik Skaaheim; Arum, Carl-Jørgen; Kulle, Bettina (Peer reviewed; Journal article, 2020)Aim: Evaluation of treatment and survival of pT1 stage (T1) bladder cancer (BC) patients diagnosed with transitional cell carcinoma of the urinary bladder in Norway. Material and methods: According to the Cancer Registry ... -
Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action
Arum, Carl-Jørgen; Gederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Hjelde, Astrid; Krokan, Hans Einar; Svaasand, Lars O.; Chen, Duan; Zhao, Chun-Mei (Journal article; Peer reviewed, 2011)Orthotopic bladder cancer model in rats mimics human bladder cancer with respect to urothelial tumorigenesis and progression. Utilizing this model at pT1 (superficial stage), we analyze the tissue responses to hexyl ... -
"Two hits - one stone" increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling
Søgaard, Caroline Krogh; Blindheim, Augun; Røst, Lisa Marie; Petrovic, Voin; Nepal, Anala; Bachke, Siri; Liabakk, Nina-Beate; Gederaas, Odrun Arna; Viset, Trond; Arum, Carl-Jørgen; Bruheim, Per; Otterlei, Marit (Journal article; Peer reviewed, 2018)Low response rate and rapid development of resistance against commonly used chemotherapeutic regimes demand new multi-targeting anti-cancer strategies. In this study, we target the stress-related roles of the scaffold ...