Browsing NTNU Open by Author "Langhammer, Arnulf"

Now showing items 61-80 of 113

    • Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools 

      Feng, Xiaoshuang; Wu, Wendy Yi-Ying; Onwuka, Justina Ucheojor; Haider, Zahra; Alcala, Karine; Smith-Byrne, Karl; Zahed, Hana; Guida, Florence; Wang, Renwei; Bassett, Julie K.; Stevens, Victoria; Wang, Ying; Weinstein, Stephanie; Freedman, Neal D.; Chen, Chu; Tinker, Lesley; Nøst, Therese Haugdahl; Koh, Woon-Puay; Muller, David; Colorado-Yohar, Sandra M.; Tumino, Rosario; Hung, Rayjean J.; Amos, Christopher I.; Lin, Xihong; Zhang, Xuehong; Arslan, Alan A.; Sánchez, Maria-Jose; Sørgjerd, Elin Pettersen; Severi, Gianluca; Hveem, Kristian; Brennan, Paul; Langhammer, Arnulf; Milne, Roger L.; Yuan, Jian-Min; Melin, Beatrice; Johansson, Mikael; Robbins, Hilary A.; Johansson, Mattias (Peer reviewed; Journal article, 2023)
      Background We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available ...

    • Lung function and exercise capacity in health and cardiopulmonary disease – Associations between resting measures of lung function and directly measured peak oxygen uptake in health, coronary artery and chronic obstructive pulmonary disease 

      Rasch-Halvorsen, Øystein (Doctoral theses at NTNU;2022:204, Doctoral thesis, 2022)
      Selv om kondisjon målt ved maksimalt oksygenopptak har veletablert prognostisk betydning både ved helse og sykdom vil den primære mekanismen for funksjonell begrensning variere betydelig. Lungefunksjonen er integrert i den ...

    • Lung function and peak oxygen uptake in chronic obstructive pulmonary disease phenotypes with and without emphysema 

      Rasch-Halvorsen, Øystein; Steinshamn, Sigurd Loe; Langhammer, Arnulf; Hassel, Erlend; Brumpton, Ben Michael; Jenssen, Haldor; Spruit, Martijn A. (Journal article; Peer reviewed, 2021)
      Previous studies of associations of forced expiratory lung volume in one second (FEV1) with peak oxygen uptake (VO2peak) in chronic obstructive pulmonary disease (COPD) have not taken sex, age and height related variance ...

    • Lung function parameters improve prediction of VO2peak in an elderly population: The Generation 100 study. 

      Hassel, Erlend; Stensvold, Dorthe; Halvorsen, Thomas; Wisløff, Ulrik; Langhammer, Arnulf; Steinshamn, Sigurd Loe (Journal article; Peer reviewed, 2017)
      Peak oxygen uptake (VO2peak) is an indicator of cardiovascular health and a useful tool for risk stratification. Direct measurement of VO2peak is resource-demanding and may be contraindicated. There exist several non-exercise ...

    • MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk 

      Surakka, Ida; Fritsche, Lars; Zhou, Wei; Backman, Joshua; Kosmicki, Jack A.; Lu, Haocheng; Brumpton, Ben Michael; Nielsen, Jonas B.; Gabrielsen, Maiken Elvestad; Skogholt, Anne Heidi; Wolford, Brooke N.; Graham, Sarah E.; Chen, Y. Eugene; Lee, Seunggeun; Kang, Hyun Min; Langhammer, Arnulf; Forsmo, Siri; Åsvold, Bjørn Olav; Styrkarsdottir, Unnur; Holm, Hilma; Gudbjartsson, Daniel F.; Stefansson, Kari; Baras, Aris; Bai, Xiaodong; Balasubramanian, Suganthi; Barnard, Leland; Blumenfeld, Andrew; Cantor, Michael; Coppola, Giovanni; Economides, Aris; Eom, Gisu; Habegger, Lukas; Hahn, Young; Hawes, Alicia; Jones, Marcus B.; Khalid, Shareef; Lotta, Luca A.; Maxwell, Evan K.; Mitnaul, Lyndon J.; Overton, John D.; Reid, Jeffrey G.; Ferreira, Manuel Allen Revez; Salerno, William; Sharma, Deepika; Shuldiner, Alan R.; Staples, Jeffrey C.; Yadav, Ashish; Abecasis, Goncalo R.; Hveem, Kristian; Willer, Cristen J. (Peer reviewed; Journal article, 2020)
      A major challenge in genetic association studies is that most associated variants fall in the non-coding part of the human genome. We searched for variants associated with bone mineral density (BMD) after enriching the ...

    • Metabolic syndrome and incidence of asthma in adults: the HUNT study 

      Brumpton, Ben Michael; Camargo, Carlos; Romundstad, Pål Richard; Langhammer, Arnulf; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2013)
      Obesity is a risk factor for incident asthma in adults, and obesity is a major component of metabolic syndrome. This study aimed to explore the associations of metabolic syndrome and its components with the cumulative ...

    • Metabolic syndrome as a risk factor for total hip or knee replacement due to primary osteoarthritis: A prospective cohort study (the HUNT study and the Norwegian arthroplasty register) 

      Hellevik, Alf Inge; Johnsen, Marianne Bakke; Langhammer, Arnulf; Baste, Valborg; Furnes, Ove; Storheim, Kjersti; Zwart, John-Anker; Flugsrud, Gunnar B; Nordsletten, Lars (Journal article; Peer reviewed, 2018)
      Objective: Biochemical changes associated with obesity may accelerate osteoarthritis beyond the effect of mechanical factors. This study investigated whether metabolic syndrome and its components (visceral obesity, ...

    • Mortality in persons with undetected and diagnosed hypertension, type 2 diabetes, and hypothyroidism, compared with persons without corresponding disease - a prospective cohort study; The HUNT Study, Norway 

      Jørgensen, Pål; Langhammer, Arnulf; Krokstad, Steinar; Forsmo, Siri (Journal article; Peer reviewed, 2017)
      Background Suggested strategies in reducing the impact of non-communicable diseases (NCD) are early diagnosing and screening. We have limited proof of benefit of population screening for NCD. Increased mortality in persons ...

    • Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk 

      Shrine, Nick; Izquierdo, Abril G.; Chen, Jing; Packer, Richard; Hall, Robert J.; Guyatt, Anna L.; Batini, Chiara; Thompson, Rebecca J.; Pavuluri, Chandan; Malik, Vidhi; Hobbs, Brian D.; Moll, Matthew; Kim, Wonji; Tal-Singer, Ruth; Bakke, Per S.; Fawcett, Katherine A.; John, Catherine; Coley, Kayesha; Piga, Noemi Nicole; Pozarickij, Alfred; Lin, Kuang; Millwood, Iona Y.; Chen, Zhengming; Li, Liming; Wijnant, Sara R A; Lahousse, Lies; Brusselle, Guy; Uitterlinden, Andre G.; Manichaikul, Ani; Oelsner, Elizabeth C.; Rich, Stephen S.; Barr, R Graham; Kerr, Shona M.; Vitart, Veronique; Brown, Michael R.; Wielscher, Matthias; Imboden, Medea; Jeong, Ayoung; Bartz, Traci M.; Gharib, Sina A.; Flexeder, Claudia; Karrasch, Stefan; Gieger, Christian; Peters, Annette; Stubbe, Beate; Hu, Xiaowei; Ortega, Victor E.; Meyers, Deborah A.; Bleecker, Eugene R.; Gabriel, Stacey B.; Gupta, Namrata; Smith, Albert Vernon; Luan, Jian'an; Zhao, Jing-Hua; Hansen, Ailin Falkmo; Langhammer, Arnulf; Willer, Cristen; Bhatta, Laxmi; Porteous, David; Smith, Blair H.; Campbell, Archie; Sofer, Tamar; Lee, Jiwon; Daviglus, Martha L.; Yu, Bing; Lim, Elise; Xu, Hanfei; O'Connor, George T.; Thareja, Gaurav; Albagha, Omar M E; Suhre, Karsten; Granell, Raquel; Faquih, Tariq O.; Hiemstra, Pieter S.; Slats, Annelies M.; Mullin, Benjamin H.; Hui, Jennie; James, Alan; Beilby, John; Patasova, Karina; Hysi, Pirro; Koskela, Jukka T.; Wyss, Annah B.; Jin, Jianping; Sikdar, Sinjini; Lee, Mikyeong; May-Wilson, Sebastian; Pirastu, Nicola; Kentistou, Katherine A.; Joshi, Peter K.; Timmers, Paul R H J; Williams, Alexander T.; Free, Robert C.; Wang, Xueyang; Morrison, John L.; Gilliland, Frank D.; Chen, Zhanghua; Wang, Carol A.; Foong, Rachel E.; Harris, Sarah E.; Taylor, Adele; Redmond, Paul; Cook, James P.; Mahajan, Anubha; Lind, Lars; Palviainen, Teemu; Lehtimäki, Terho; Raitakari, Olli T.; Kaprio, Jaakko; Rantanen, Taina; Pietiläinen, Kirsi H.; Cox, Simon R.; Pennell, Craig E.; Hall, Graham L.; Gauderman, W James; Brightling, Chris; Wilson, James F.; Vasankari, Tuula; Laitinen, Tarja; Salomaa, Veikko; Mook-Kanamori, Dennis O.; Timpson, Nicholas J.; Zeggini, Eleftheria; Dupuis, Josée; Hayward, Caroline; Brumpton, Ben Michael; Langenberg, Claudia; Weiss, Stefan; Homuth, Georg; Schmidt, Carsten Oliver; Probst-Hensch, Nicole; Jarvelin, Marjo-Riitta; Morrison, Alanna C.; Polasek, Ozren; Rudan, Igor; Lee, Joo-Hyeon; Sayers, Ian; Rawlins, Emma L.; Dudbridge, Frank; Silverman, Edwin K.; Strachan, David P.; Walters, Robin G.; Morris, Andrew P.; London, Stephanie J.; Cho, Michael H.; Wain, Louise V.; Hall, Ian P.; Tobin, Martin D. (Peer reviewed; Journal article, 2023)
      Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 ...

    • Multimorbidity in Finnish and Swedish speaking Finns; association with daily habits and socioeconomic status – Nordic EpiLung cross-sectional study 

      Andersén, Heidi; Kankaanranta, Hannu; Tuomisto, Leena E.; Piirilä, Päivi; Sovijärvi, Anssi; Langhammer, Arnulf; Backman, Helena; Lundbäck, Bo; Rönmark, Eva; Lehtimäki, Lauri; Ilmarinen, Pinja (Peer reviewed; Journal article, 2021)
      Multimorbidity is an emerging public health priority. This study aims to assess the role of lifestyle and socioeconomic status in the prevalence of multimorbidity and chronic diseases by using two language groups that are ...

    • National health registries – a ‘goldmine’ for studying non-communicable disease occurrence in Norway – the NCDNOR project 

      Nystad, Wenche; Hjellvik, Vidar; Larsen, Inger Kristin; Robsahm, Trude Eid; Sund, Erik Reidar; Krokstad, Steinar; Hopstock, Laila Arnesdatter; Grimsgaard, Anne Sameline; Langhammer, Arnulf; Bramness, Jørgen Gustav; Wisløff, Torbjørn; Lergenmuller, Simon; Dalene, Knut Eirik; Meyer, Haakon Eduard; Holvik, Kristin; Helgeland, Jon; Karlstad, Øystein; Ariansen, Inger (Peer reviewed; Journal article, 2023)
      To estimate occurrence of non-communicable diseases (NCDs) over the life-course in the Norwegian population, national health registries are a vital source of information since they fully represent the entire non-institutionalised ...

    • No association between circulating concentrations of vitamin D and risk of lung cancer: An analysis in 20 prospective studies in the Lung Cancer Cohort Consortium (LC3) 

      Muller, David C.; Hodge, Allison M.; Fanidi, Anouar; Albanes, Demetrius; Mai, Xiao-Mei; Shu, Xiao Ou; Weinstein, Stephanie J.; Larose, Tricia L; Zhang, Xuehong; Han, Jingquan; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Ma, Jing; Gaziano, John Michael; Sesso, Howard D.; Stevens, Victoria L.; McCullough, Marjorie L.; Layne, Tracy M.; Prentice, Ross; Pettinger, Mary; Thomson, Cynthia A.; Zheng, Wei; Gao, Yutang; Rothman, Nathaniel; Xiang, Yong-Bing; Cai, Hui; Wang, Rui; Yuan, Jian-Min; Koh, Woon-Puay; Butler, Lesley M.; Cai, Qiuyin; Blot, William James; Wu, Jie; Ueland, Per Magne; Midttun, Øivind; Langhammer, Arnulf; Hveem, Kristian; Johansson, Mikael B.; Hultdin, Johan; Grankvist, Kjell; Arslan, Alan A.; Le Marchand, Loïc; Severi, Gianluca; Johansson, Mattias; Brennan, Paul (Journal article; Peer reviewed, 2018)
      Background There is observational evidence suggesting that high vitamin D concentrations may protect against lung cancer. To investigate this hypothesis in detail, we measured circulating vitamin D concentrations in ...

    • Ovulation prevalence in women with spontaneous normal-length menstrual cycles - A population-based cohort from HUNT3, Norway 

      Prior, Jerilynn C.; Næss, Marit; Langhammer, Arnulf; Forsmo, Siri (Journal article, 2015)
      Background: Ovulatory menstrual cycles are essential for women’s fertility and needed to prevent bone loss. There is a medical/cultural expectation that clinically normal menstrual cycles are inevitably ovulatory. ...

    • Physical Activity and Incident Asthma in Adults: The HUNT Study, Norway. 

      Brumpton, Ben Michael; Langhammer, Arnulf; Ferreira, Manuel A R; Chen, Yue; Mai, Xiao-Mei (Journal article; Peer reviewed, 2016)
      Objective: We aimed to investigate the associations of physical activity and change in physical activity with incident asthma in a cohort of Norwegian adults. Design: We conducted a prospective cohort study using ...

    • Potential causal associations of serum 25-hydroxyvitamin D with lipids: a Mendelian randomization approach of the HUNT study 

      Mai, Xiao-Mei; Videm, Vibeke; Sheehan, Nuala A.; Chen, Yue; Langhammer, Arnulf; Sun, Yi-Qian (Journal article; Peer reviewed, 2018)
      Background: Observational studies have shown consistent associations between higher circulating 25-hydroxyvitamin D [25(OH)D] levels and favorable serum lipids. We sought to investigate if such associations were causal. ...

    • Prediagnosis Leisure-Time Physical Activity and Lung Cancer Survival: A Pooled Analysis of 11 Cohorts 

      Yang, Jae Jeong; Yu, Danxia; White, Emily; Lee, Dong Hoon; Blot, William; Robien, Kim; Sinha, Rashmi; Park, Yikyung; Takata, Yumie; Gao, Yu-Tang; Smith-Byrne, Karl; Monninkhof, Evelyn M; Kaaks, Rudolf; Langhammer, Arnulf; Borch, Kristin Benjaminsen; Al-Shaar, Laila; Lan, Qing; Sørgjerd, Elin Pettersen; Zhang, Xuehong; Zhu, Clair; Chirlaque, María Dolores; Severi, Gianluca; Overvad, Kim; Sacerdote, Carlotta; Aune, Dagfinn; Johansson, Mattias; Smith-Warner, Stephanie A; Zheng, Wei; Shu, Xiao-Ou (Peer reviewed; Journal article, 2022)
      Background Little is known about the association between physical activity before cancer diagnosis and survival among lung cancer patients. In this pooled analysis of 11 prospective cohorts, we investigated associations ...

    • Prediagnostic calcium intake and lung cancer survival: A pooled analysis of 12 cohort studies 

      Yu, Danxia; Takata, Yumie; Smith-Warner, Stephanie A.; Blot, William; Sawada, Norie; White, Emily; Freedman, Neal; Robien, Kim; Giovannucci, Edward; Zhang, Xuehong; Park, Yikyung; Gao, Yu-Tang; Chlebowski, Rowan T.; Langhammer, Arnulf; Yang, Gong; Severi, Gianluca; Manjer, Jonas; Khaw, Kay-Tee; Weiderpass, Elisabete; Liao, Linda M.; Caporaso, Neil; Krokstad, Steinar; Hveem, Kristian; Sinha, Rashmi; Ziegler, Regina; Tsugane, Shoichiro; Xiang, Yong-Bing; Johansson, Mattias; Zheng, Wei; Shu, Xiao-Ou (Journal article, 2017)
      Background: Lung cancer is the leading cause of cancer death. Little is known about whether prediagnostic nutritional factors may affect survival. We examined the associations of prediagnostic calcium intake from foods ...

    • Prevalence of, and work-related risk factors for, hand eczema in a Norwegian general population (The HUNT Study) 

      Vindenes, Hilde Kristin; Svanes, Cecilie; Lygre, Stein Håkon Låstad; Hollund, Bjørg Eli; Langhammer, Arnulf; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2017)
      Background Chemical exposures at work and at home may cause hand eczema. However, this has been scarcely described for Norway. Objectives To investigate the prevalence of, and occupational risk factors for, hand eczema ...

    • Prolonged Sitting, Its Combination With Physical Inactivity and Incidence of Lung Cancer: Prospective Data From the HUNT Study 

      Jiang, Lin; Sun, Yi-Qian; Brumpton, Ben Michael; Langhammer, Arnulf; Chen, Yue; Nilsen, Tom Ivar Lund; Mai, Xiao-Mei (Journal article; Peer reviewed, 2019)
      Background: Prolonged sitting as a major sedentary behavior potentially contributes to illness, but its relation with lung cancer risk is unclear. Prolonged sitting can be presented in physically active or inactive ...

    • Proton pump inhibitors and fracture risk. The HUNT study, Norway. 

      Hoff, Mari; Skovlund, Eva; Skurtveit, Svetlana; Meyer, Haakon E; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Forsmo, Siri; Abrahamsen, Bo; Schei, Berit (Journal article; Peer reviewed, 2019)
      Summary Proton pump inhibitors (PPIs) have been linked to increased risk of fracture; the data have, however, been diverging. We did not find any increased risk of fractures among users of PPIs in a Norwegian population ...