Blar i NTNU Open på forfatter "Sletmoen, Marit"
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Interaksjoner mellom galektiner og deres substrater
Wik, Viktoria Rosfjord (Master thesis, 2019)Glykoforskning representerer et nytt og spennende forskningsfelt som handler om å forstå funksjonen og strukturen til glykaner, og det gir håp om spennende utvikling innen områder som medisin, energigenerering og ... -
Microarrays for High Throughput Analysis of Cellular Heterogeneity
Dunker, Karen (Master thesis, 2017)The importance of cellular heterogeneity within cell populations has been increasingly realized in recent years. As a result, there has been a focus on developing methods for single cell analysis. µCP represents a cheap, ... -
Microarrays for the study of compartmentalized microorganisms in alginate microbeads and (W/O/W) double emulsions
Håti, Armend Gazmeno; Arnfinnsdottir, Nina Bjørk; Østevold, Camilla; Sletmoen, Marit; Etienne, Gianluca; amstad, esther; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2016)Understanding of cells has mainly been achieved through analysis of average properties of large cellular populations. The increased awareness of cellular heterogeneity in various biological systems, spans from single ... -
Microscale tools for the development of bacterial microarrays
Arnfinnsdottir, Nina Bjørk (Doctoral thesis at NTNU;2016:61, Doctoral thesis, 2016)Heterogeneity within bacterial populations is a phenomenon that has gained much interest over the last decades. It has been shown that even isogeneous colonies under homogeneous conditions can display different phenotypes. ... -
Mucins: Galectin 3 interactions measured by atomic force microscopy - Carbohydrate antigens in human health and disease
Bugge, Ragna Emilie (Master thesis, 2017)Galectins are a family of widely distributed sugar-binding proteins characterized by a specificity for β-galactosides. These lectins are assumed to be involved in diverse biological phenomena critical for multicellular ... -
Nanoscale characterization of mechanisms for bacterial adhesion to mucosal surfaces
Dunker, Karen (Doctoral theses at NTNU;2023:289, Doctoral thesis, 2023)Glycan-based interactions have been the subject of an increasing number of studies in recent years, as their importance in biological systems is becoming more understood. As glycans are present on the majority of cell ... -
Påvirkning av tapet av CMAH genet på hydrofobisiteten til lymfecelleoverflater
Pedersen, Kristine Mathingsdal (Master thesis, 2019)Overflaten til alle eukaryote celler er dekket av et tett lag med glykaner som ofte er terminert med sialinsyrer. N-acetylneuraminsyre (Neu5Ac) og N-glykolylneuraminsyre (Neu5Gc) er de vanligste, der sistnevnte består av ... -
Preparation of cellular microarrays using microcontact printing
Dekov, Maren (Master thesis, 2019)Verktøy som forenkler analyse av enkeltceller har i de siste årene blitt utviklet som følge av en nylig oppdaget viktighet av cellulær heterogenitet. Et eksempel på et slikt verktøy som kan brukes for enkeltcelle analyse ... -
Quantification of Specific Adhesive Interactions between Wild Type and Mutant Saccharomyces cerevisiae and relevant Lectins using Optical Tweezers.
Bringe, Katrine (Master thesis, 2014)The cell surface of yeast cells are covered with a specific set of molecules that are involved in cellular communication, adhesion and microbial infection. In an effort to expand the knowledge of the relevant interactions ... -
Responsive Hydrogels for Label-Free Signal Transduction within Biosensors
Gawel, Kamila; Barriet, David; Sletmoen, Marit; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2010)Hydrogels have found wide application in biosensors due to their versatile nature. This family of materials is applied in biosensing either to increase the loading capacity compared to two-dimensional surfaces, or to support ... -
Rheology of skin mucus from yolk-sac salmon fry
Nordgård, Catherine Taylor; Gomez de la Torre Canny, Sol; Dunker, Karen; Sletmoen, Marit; Bakke, Ingrid (Journal article; Peer reviewed, 2020)As part of our project “Microbial contributions to the Atlantic salmon (Salmo salar) skin mucosal barrier” we have explored techniques to investigate and characterise the rheological properties of the skin mucus of yolk-sac ... -
Single molecule dynamic force spectroscopy of alginate-epimerase interactions using optical tweezers
Håti, Armend Gazmeno (Master thesis, 2012)Alginate, a naturally occurring polysaccharide found in various cell lines, is synthesized as a homopolymer polymannuronic acid also known as mannuronan or PolyM. Conversion of the polymers subunits β-D-mannuronic acid (M) ... -
Studies of MUC1 - Gal3 lectin interaction by the sensitive force probe Optical Tweezers (OT)
Haug, Øystein (Master thesis, 2017)Aberrant glycosylation patterns of membrane-bound proteins have been observed to be a universal feature of malignant cells. Members of the mucin family of glycoproteins form one of the major carriers of aberrant glycosylation, ... -
The breast cancer-associated glycoforms of MUC1, MUC1-Tn and sialyl-Tn, are expressed in COSMC wild-type cells and bind the C-type lectin MGL
Beatson, Richard; Maurstad, Gjertrud; Picco, Gianfranco; Arulappu, Appitha; Coleman, Julia; Wandell, Hans H; Clausen, Henrik; Mandel, Ulla; Taylor-Papadimitriou, Joyce; Sletmoen, Marit; Burchell, Joy (Journal article, 2015)Aberrant glycosylation occurs in the majority of human cancers and changes in mucin-type O-glycosylation are key events that play a role in the induction of invasion and metastases. These changes generate novel cancer-specific ... -
The Design of Simple Bacterial Microarrays: Development towards Immobilizing Single Living Bacteria on Predefined Micro-Sized Spots on Patterned Surfaces
Arnfinnsdottir, Nina Bjørk; Ottesen, Vegar; Lale, Rahmi; Sletmoen, Marit (Journal article; Peer reviewed, 2015)In this paper we demonstrate a procedure for preparing bacterial arrays that is fast, easy, and applicable in a standard molecular biology laboratory. Microcontact printing is used to deposit chemicals promoting bacterial ... -
The Role of Glycans in Bacterial Adhesion to Mucosal Surfaces: How Can Single-Molecule Techniques Advance Our Understanding?
formosa dague, cecile; Castelain, Mickael; Martin-Yken, Helene; Dunker, Karen; dague, etienne; Sletmoen, Marit (Journal article; Peer reviewed, 2018)Bacterial adhesion is currently the subject of increased interest from the research community, leading to fast progress in our understanding of this complex phenomenon. Resent research within this field has documented the ... -
Thin film breakage in oil–in–water emulsions, a multidisciplinary study
Aarøen, Ola; Riccardi, Enrico; van Erp, Titus Sebastiaan; Sletmoen, Marit (Peer reviewed; Journal article, 2022)Coalescence is a critical phenomenon in separation and transport processes. An improved understanding of coalescence can enhance current models predicting emulsion stability and separation. We here report a combined ... -
A Titratable Cell Lysis-on-Demand System for Droplet-Compartmentalised Ultrahigh-Throughput Screening in Functional Metagenomics and Directed Evolution
Wong, Che Fai Alex; Van Vliet, L.; Bhujbal, Swapnil Vilas; Guo, Chengzhi; Sletmoen, Marit; Stokke, Bjørn Torger; Hollfelder, Florian; Lale, Rahmi (Journal article; Peer reviewed, 2021)Water-in-oil emulsion droplets are an attractive format for ultrahigh-throughput screening in functional metagenomics and directed evolution applications that allow libraries with more than 107 members to be characterized ... -
Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactions
Sletmoen, Marit; Gerken, Thomas A.; Stokke, Bjørn Torger; Burchell, Joy; Brewer, C. Fred (Journal article; Peer reviewed, 2018)The mucin-type O-glycome in cancer aberrantly expresses the truncated glycans Tn (GalNAcα1-Ser/Thr) and STn (Neu5Acα2,6GalNAcα1-Ser/Thr). However, the role of Tn and STn in cancer and other diseases is not well understood. ... -
Use of atomic force microscopy to study bacterial adhesion to mucins
Bugge, Tove Enmo (Master thesis, 2020)I høyere organismers indre organer, som luftveiene, mage- og tarmkanalen og det urogenitale system, dekkes overflateepitel av et slimlag, også kalt mucus. Mucus dekker også huden til amfibier, snegler og fisk. Mucus spiller ...