Blar i NTNU Open på forfatter "Sarno, Antonio"
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TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data
Lefol, Yohan Pierre; Korfage, Tom; Mjelle, Robin; Prebensen, Christian Haugland; Lüders, Torben; Müller, Bruno; Krokan, Hans Einar; Sarno, Antonio; Alsøe, Lene; Berdal, Jan-Erik; Sætrom, Pål; Nilsen, Hilde; Domanska, Diana (Peer reviewed; Journal article, 2023)Improved transcriptomic sequencing technologies now make it possible to perform longitudinal experiments, thus generating a large amount of data. Currently, there are no dedicated or comprehensive methods for the analysis ... -
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG
Alsøe, Lene; Sarno, Antonio; Carracedo Huroz, Sergio; Domanska, Diana Ewa; Dingler, Felix; Lirussi, Lisa; Sengupta, Tanima; Tekin, Nuriye Basdag; Jobert, Laure; Alexandrov, Ludmil B.; Galashevskaya, Anastasia; Rada, Cristina; Sandve, Geir Kjetil; Rognes, Torbjørn; Krokan, Hans Einar; Nilsen, Hilde Loge (Journal article; Peer reviewed, 2017)Both a DNA lesion and an intermediate for antibody maturation, uracil is primarily processed by base excision repair (BER), either initiated by uracil-DNA glycosylase (UNG) or by single-strand selective monofunctional ... -
Uracil in DNA - necessary intermediate for antibody maturation and mutagenic lesion
Sarno, Antonio (Doctoral thesis at NTNU;2015:153, Doctoral thesis, 2015)Uracil in DNA - et viktig mellomprodukt for adaptiv immunitet og mutagen skade Uracil er en av fire nukleobaser i RNA, men små mengder kan også befinne seg i DNA. Det er to kilder til genomisk uracil: misinkorporering ... -
Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil
Sarno, Antonio; Lundbæk, Marie Benner; Liabakk, Nina-Beate; Aas, Per Arne; Mjelle, Robin; Hagen, Lars; Sousa, Mirta; Krokan, Hans Einar; Kavli, Bodil Merete (Journal article; Peer reviewed, 2019)UNG is the major uracil-DNA glycosylase in mammalian cells and is involved in both error-free base excision repair of genomic uracil and mutagenic uracil-processing at the antibody genes. However, the regulation of UNG in ... -
UV degradation of natural and synthetic microfibers causes fragmentation and release of polymer degradation products and chemical additives
Sørensen, Lisbet; Groven, Anette Synnøve; Hovsbakken, Ingrid Alver; Del Puerto, Oihane; Krause, Daniel Franklin; Sarno, Antonio; Booth, Andy (Peer reviewed; Journal article, 2020)A high proportion of the total microplastic (MP) load in the marine environment has been identified as microfibers (MFs), with polyester (PET) and polyamide (PA) typically found in the highest abundance. The potential for ... -
UV degradation of natural and synthetic microfibers causes fragmentation and release of polymer degradation products and chemical additives
Sørensen, Lisbet; Groven, Anette Synnøve; Hovsbakken, Ingrid Alver; Del Puerto, Oihane; Krause, Daniel Franklin; Sarno, Antonio; Booth, Andrew (Peer reviewed; Journal article, 2020)A high proportion of the total microplastic (MP) load in the marine environment has been identified as microfibers (MFs), with polyester (PET) and polyamide (PA) typically found in the highest abundance. The potential for ...