Blar i NTNU Open på forfatter "Rø, Torstein Baade"
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Paediatric goal management training in patients with acquired brain injury: study protocol for a randomised controlled trial
Hypher, Ruth Elizabeth; Brandt, Anne Elisabeth; Risnes, Kari Ravndal; Rø, Torstein Baade; Skovlund, Eva; Andersson, Stein; Finnanger, Torun Gangaune; Stubberud, Jan (Journal article; Peer reviewed, 2019)Introduction Compromised integrity of the brain due to paediatric acquired brain injury (pABI) has been associated with cognitive impairment, particularly executive dysfunction, in addition to somatic and emotional symptoms ... -
Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration
Vandsemb, Esten Nymoen; Bertilsson, Helena; Abdollahi, Pegah; Størkersen, Øystein; Våtsveen, Thea Kristin; Rye, Morten Beck; Rø, Torstein Baade; Børset, Magne; Slørdahl, Tobias Schmidt (Journal article; Peer reviewed, 2016)Background: PRL-3 is a phosphatase implicated in oncogenesis in multiple cancers. In some cancers, notably carcinomas, PRL-3 is also associated with inferior prognosis and increased metastatic potential. In this study we ... -
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration
Hjort, Magnus Aasved; Hov, Håkon; Abdollahi, Pegah; Vandsemb, Esten; Fagerli, Unn-Merete; Lund, Bendik; Slørdahl, Tobias Schmidt; Børset, Magne; Rø, Torstein Baade (Journal article; Peer reviewed, 2018)Background Phosphatase of regenerating liver-3 (PRL-3) is implicated in oncogenesis of hematological and solid cancers. PRL-3 expression increases metastatic potential, invasiveness and is associated with poor prognosis. ... -
Phosphatase of regenerating liver-3 as a target for treatment of B cell malignancies
Hjort, Magnus Aassved (Doctoral theses at NTNU;2018:241, Doctoral thesis, 2018)PRL-3 som et angrepsmål i behandlingen av B-cellekreft Akutt lymfatisk leukemi (ALL), Hodgkin lymfom (HL) og myelomatose er kreftsykdommer som oppstår fra B-lymfocytter. Disse cellene er en del av kroppens immunforsvar. ... -
Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance
Hjort, Magnus Aassved; Abdollahi, Pegah; Vandsemb, Esten Nymoen; Fenstad, Mona H.; Lund, Bendik; Slørdahl, Tobias Schmidt; Børset, Magne; Rø, Torstein Baade (Journal article; Peer reviewed, 2017)Phosphatase of regenerating liver-3 (PRL-3/PTP4A3) is upregulated in multiple cancers, including BCR-ABL1- and ETV6-RUNX-positive acute lymphoblastic leukemia (ALL). With this study, we aim to characterize the biological ... -
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma
Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved; Andreassen, Trygve; Misund, Kristine; Slørdahl, Tobias Schmidt; Rø, Torstein Baade; Sponaas, Anne-Marit; Moestue, Siver Andreas; Bruheim, Per; Børset, Magne (Peer reviewed; Journal article, 2021)Cancer cells often depend on microenvironment signals from molecules such as cytokines for proliferation and metabolic adaptations. PRL‐3, a cytokine‐induced oncogenic phosphatase, is highly expressed in multiple myeloma ... -
Predictors of Functional School Outcome in Children With Pediatric Acquired Brain Injury
Stubberud, Jan Egil; Hypher, Ruth Elizabeth; Brandt, Anne Elisabeth; Finnanger, Torun Gangaune; Skovlund, Eva; Andersson, Stein; Risnes, Kari; Rø, Torstein Baade (Peer reviewed; Journal article, 2022)Objective: Among the variety of domains that may be impacted after pediatric acquired brain injury (pABI) are functional school outcomes. The purpose of this study was to identify demographic, medical, and psychological ... -
Prevalence and associations of impaired awareness of hypoglycemia in a pediatric type 1 diabetes population – The Norwegian Childhood Diabetes Registry
Hatle, Håvard; Skrivarhaug, Torild; Bjørgaas, Marit Ragnhild Rokne; Åsvold, Bjørn Olav; Rø, Torstein Baade (Peer reviewed; Journal article, 2024)Aims To determine the prevalence and associations of impaired awareness of hypoglycemia (IAH) in pediatric type 1 diabetes. Methods Nationwide, population-based cross-sectional study with 51 % participation. Participants ... -
PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2
Vandsemb, Esten; Rye, Morten Beck; Steiro, Ida Johnsen; Elsaadi, Samah; Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Sponaas, Anne-Marit; Børset, Magne; Abdollahi, Pegah (Peer reviewed; Journal article, 2021)Multiple myeloma (MM) is an incurable hematologic malignancy resulting from the clonal expansion of plasma cells. MM cells are interacting with components of the bone marrow microenvironment such as cytokines to survive ... -
PRL-3–a signaling hub in Multiple Myeloma
Abdollahi, Pegah (Doctoral theses at NTNU;2017:131, Doctoral thesis, 2017)PRL-3 -en sentral aktør i myelomatsoecellens signalformidling: Myelomatose er en kreftform som oppstår i plasmaceller, den ferdig differensierte formen for B lymfocytter. Et kjennetegn på myelomatose er dens lokalisasjon ... -
Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation
Rø, Anne Dorthea; Simpson, Melanie Rae; Rø, Torstein Baade; Storrø, Ola; Johnsen, Roar; Videm, Vibeke; Øien, Torbjørn (Journal article; Peer reviewed, 2017)Background In the randomized, controlled study Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT), maternal probiotic supplementation reduced the incidence of atopic dermatitis (AD) in the ... -
Rehabilitation of executive function in chronic paediatric brain injury: a randomized controlled trial
Brandt, Anne Elisabeth; Finnanger, Torun Gangaune; Hypher, Ruth Elizabeth; Rø, Torstein Baade; Skovlund, Eva; Andersson, Stein; Risnes, Kari; Stubberud, Jan Egil (Peer reviewed; Journal article, 2021)Background Impaired executive functions (EFs, i.e., purposeful, goal-directed behaviour) cause significant disability after paediatric acquired brain injury (pABI) warranting efficient interventions. Goal Management Training ... -
Requests for new oral antibiotic prescriptions in children within 2 days: a Norwegian population-based study
Bergene, Elin Høien; Nordeng, Hedvig Marie Egeland; Rø, Torstein Baade; Steinsbekk, Aslak (Journal article; Peer reviewed, 2018)Background Children commonly refuse to take antibiotics, which may induce parents to request new antibiotic prescriptions with different pharmaceutical characteristics. Objectives To investigate prescription changes ... -
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3
Abdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Holien, Toril; Sponaas, Anne-Marit; Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Børset, Magne (Journal article; Peer reviewed, 2016)Phosphatase of regenerating liver-3 (PTP4A3/PRL-3) is a dual-specificity phosphatase that is upregulated in various types of cancers and is related to poor prognosis and aggressive tumor behavior. The expression level of ... -
Strategies parents use to give children oral medicine: a qualitative study of online discussion forums
Bergene, Elin Høien; Rø, Torstein Baade; Steinsbekk, Aslak (Journal article; Peer reviewed, 2017)Aim: The aim of this study was to describe strategies parents use to give oral medicine to children. Methods: We conducted an Internet-based qualitative study of posts from online forums where parents discussed how to give ... -
Targeting phosphoglycerate dehydrogenase in multiple myeloma
Elsaadi, Samah; Steiro, Ida Johnsen; Abdollahi, Pegah; Vandsemb, Esten; Yang, Rui; Slørdahl, Tobias Schmidt; Rø, Torstein Baade; Menu, Eline; Sponaas, Anne-Marit; Børset, Magne (Peer reviewed; Journal article, 2021)Background: Multiple myeloma (MM) is a hematological malignancy characterized by the clonal expansion of plasma cells in the bone marrow. To date, this disease is still incurable and novel therapeutic approaches are required. ... -
Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells
Müller, Rebekka; Misund, Kristine; Holien, Toril; Bachke, Siri; Gilljam, Karin Margaretha; Våtsveen, Thea Kristin; Rø, Torstein Baade; Bellacchio, E.; Sundan, Anders; Otterlei, Marit (Journal article; Peer reviewed, 2013)Multiple myeloma is a hematological cancer that is considered incurable despite advances in treatment strategy during the last decade. Therapies targeting single pathways are unlikely to succeed due to the heterogeneous ... -
Use of oral medicines for short-term illnesses in children - Perspectives on prescribing, dispensing and administration
Bergene, Elin Høien (Doctoral theses at NTNU;2018:332, Doctoral thesis, 2018)Summary About half of all children receive one or more prescriptions per year, most commonly oral medicines for short-term illnesses. Choosing an appropriate medicine for a specific child can be challenging due to the ... -
Validity of the Behavioural Assessment of the Dysexecutive Syndrome for Children (BADS-C) in children and adolescents with pediatric acquired brain injury
Romundstad, Bendik; Solem, Stian; Brandt, Anne Elisabeth; Hypher, Ruth Elizabeth; Risnes, Kari; Rø, Torstein Baade; Stubberud, Jan Egil; Finnanger, Torun Gangaune (Peer reviewed; Journal article, 2022)The Behavioural Assessment of the Dysexecutive Syndrome for Children (BADS-C) was developed to address the need for a standardized ecologically valid test of executive function (EF) in the pediatric population. Our study ...