dc.contributor.author | Saberi, Abbas | |
dc.contributor.author | Bakhsheshi-Rad, Hamid Reza | |
dc.contributor.author | Ismail, Ahmad Fauzi | |
dc.contributor.author | Sharif, Safian | |
dc.contributor.author | Razzaghi, Mahmood | |
dc.contributor.author | Ramakrishna, Seeram | |
dc.contributor.author | Berto, Filippo | |
dc.date.accessioned | 2023-02-09T12:49:05Z | |
dc.date.available | 2023-02-09T12:49:05Z | |
dc.date.created | 2022-04-11T12:49:20Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Metals. 2022, 12 (2), . | en_US |
dc.identifier.issn | 2075-4701 | |
dc.identifier.uri | https://hdl.handle.net/11250/3049727 | |
dc.description.abstract | Magnesium-based composites have recently been studied as biodegradable materials for preparing orthopedic implants. In this article, the graphene oxide (GO) and GO-Cu nanosystem has been homogenously dispersed as a reinforcement in the matrix of Mg-Zn (MZ) alloy using the semi powder metallurgy (SPM) method, and subsequently, the composite has been successfully manufactured using the spark plasma sintering (SPS) process. GO and GO-Cu reinforced composite displayed a higher compressive strength (~55%) than the unreinforced Mg-Zn sample. GO and GO-Cu dual nanofillers presented a synergistic effect on enhancing the effectiveness of load transfer and crack deflection in the Mg-based matrix. Besides, the GO-Cu dual nanofillers displayed a synergistic influence on antibacterial activity through combining the capturing influences of GO nanosheets with the killing influences of Cu. However, electrochemical and in-vitro immersion evaluation showed that Cu-GO reinforcement had a slightly negative effect on the corrosion behavior of the Mg-Zn sample, but the incorporation of GO enhanced corrosion resistance of the composite. Moreover, MZ/GO and MZ/GO-Cu nanocomposites showed acceptable cytotoxicity to MG-63 cells and revealed a high potential for use as an orthopedic implant material. Based on the research results, MZ/GO-Cu nanocomposite could be used in bone tissue engineering applications. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | The Effect of Co-Encapsulated GO-Cu Nanofillers on Mechanical Properties, Cell Response, and Antibacterial Activities of Mg-Zn Composite | en_US |
dc.title.alternative | The Effect of Co-Encapsulated GO-Cu Nanofillers on Mechanical Properties, Cell Response, and Antibacterial Activities of Mg-Zn Composite | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 16 | en_US |
dc.source.volume | 12 | en_US |
dc.source.journal | Metals | en_US |
dc.source.issue | 2 | en_US |
dc.identifier.doi | 10.3390/met12020207 | |
dc.identifier.cristin | 2016709 | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |