• Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells 

      Samdal, Helle; Sandmoe, Malin Alise; Olsen, Lene Christin; Jarallah, Elaf Ali Hadi; Høiem, Therese Stork; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild (Journal article, 2018)
      The omega‐3 fatty acid docosahexaenoic acid (DHA) is known as an anticancer agent. Colorectal cancer (CRC) cells exhibit different sensitivity toward DHA, but the mechanisms involved are still unclear. Gene expression ...
    • Molecular insight into a new low-affinity xylan binding module from the xylanolytic gut symbiont Roseburia intestinalis 

      Leth, Maria Louise; Ejby, Morten; Madland, Eva; Kitaoku, Yoshihito; Slotboom, Dirk J.; Guskov, Albert; Aachmann, Finn Lillelund; Hachem, Maher Abou (Peer reviewed; Journal article, 2019)
      Efficient capture of glycans, the prime metabolic resources in the human gut, confers a key competitive advantage for gut microbiota members equipped with extracellular glycoside hydrolases (GHs) to target these substrates. ...
    • Past, present and future of zebrafish in epilepsy research 

      Yaksi, Emre; Jamali, Ahmed; Diaz Verdugo, Carmen; Jurisch-Yaksi, Nathalie (Journal article; Peer reviewed, 2021)
      Animal models contribute greatly to our understanding of brain development and function as well as its dysfunction in neurological diseases. Epilepsy research is a very good example of how animal models can provide us with ...
    • PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2 

      Vandsemb, Esten; Rye, Morten Beck; Steiro, Ida Johnsen; Elsaadi, Samah; Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Sponaas, Anne-Marit; Børset, Magne; Abdollahi, Pegah (Peer reviewed; Journal article, 2021)
      Multiple myeloma (MM) is an incurable hematologic malignancy resulting from the clonal expansion of plasma cells. MM cells are interacting with components of the bone marrow microenvironment such as cytokines to survive ...