Blar i Publikasjoner fra CRIStin - NTNU på tidsskrift "Acta Anaesthesiologica Scandinavica"

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    • Acute kidney injury in intensive care patients: Incidence, time course, and risk factors 

      Mo, Skule; Bjelland, Thor Wilhelm; Nilsen, Tom Ivar Lund; Klepstad, Pål (Peer reviewed; Journal article, 2022)
      Background Acute kidney injury (AKI) is frequent and influences the prognosis of intensive care unit (ICU) patients. The aim of this study was to estimate the incidence, time-course, risk factors, and mortality of AKI ...

    • Burnout among intensive care nurses, physicians and leaders during the COVID-19 pandemic: A national longitudinal study 

      Hovland, Ingvild Strand; Skogstad, Laila; Diep, Lien My; Ekeberg, Øivind; Ræder, Johan; Stafseth, Siv Anna Ulla-Britt Karlsson; Hem, Erlend; Karin Isaksson, Isaksson; Lie, Irene (Peer reviewed; Journal article, 2024)
      Background Burnout is frequent among intensive care unit (ICU) healthcare professionals and may result in medical errors and absenteeism. The COVID-19 pandemic caused additional strain during working hours and also ...

    • Clinical and ethical aspects of palliative sedation with propofol—A retrospective quantitative and qualitative study 

      Fredheim, Olav Magnus; Skulberg, Ingeborg M; Magelssen, Morten; Steine, Siri (Peer reviewed; Journal article, 2020)
      Background The anesthetic propofol is often mentioned as a drug that can be used in palliative sedation. The existing literature of how to use propofol in palliative sedation is scarce, with lack of information about ...

    • Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized controlled study 

      Mostad, Dagmar; Klepstad, Pål; Follestad, Turid; Pleym, Hilde (Peer reviewed; Journal article, 2021)
      Background: In general anaesthesia practice a fresh gas flow (FGF) of ≥0.5 L/min is usually applied. Automated gas delivery devices are developed to reduce volatile anaesthetic consumption by limiting gas flow. This study ...

    • Effects of Adrenaline on maternal and fetal fentanyl absorption in epidural analgesia: a randomized trial 

      Haidl, Frans Felxi; Rosseland, Leiv Arne; Spigset, Olav; Dahl, Vegard (Journal article; Peer reviewed, 2018)
      Background The combination of low‐dose local anesthesia and lipophilic opioids such as fentanyl is established as a standard solution for labor epidural analgesia. Fentanyl increases efficacy, but may have negative effects ...

    • Filled prescriptions for opioids among children and adolescents – A nationwide study from 2010 to 2018 

      Hamina, Aleksi; Handal, Marte; Fredheim, Olav; Clausen, Thomas; Chen, Li-Chia; Skurtveit, Svetlana Ondrasova (Peer reviewed; Journal article, 2021)
      Background Prescribing opioids for children and adolescents should be reserved for advanced life-limiting diseases and moderate-to-severe acute pain. Pediatric codeine use is discouraged by several authorities, but the ...

    • Frailty and survival in elderly intensive care patients in Norway 

      Andersen, Finn Husøy; Haaland, Øystein Ariansen; Klepstad, Pål; Flaatten, Hans (Journal article; Peer reviewed, 2021)
      Background Today, 10%-15% of Norwegian intensive care patients are ≥80 years. This proportion will increase significantly over the next 20 years, but it is unlikely that resources for intensive care increase correspondingly. ...

    • Open chest and pericardium facilitate transpulmonary passage of venous air emboli 

      Storm, Benjamin; Halvorsen, Per Steinar; Skulstad, Helge; Dybwik, Knut Gustav; Schjalm, Camilla; Christiansen, Dorte; Wisløff-Aase, Kristin; Fosse, Erik; Braaten, Tonje Bjørndal; Nielsen, Erik Waage; Mollnes, Tom Eirik (Peer reviewed; Journal article, 2021)
      Background Transpulmonary passage of air emboli can lead to fatal brain- and myocardial infarctions. We studied whether pigs with open chest and pericardium had a greater transpulmonary passage of venous air emboli than ...

    • Pharmacokinetics of propofol in severely obese surgical patients 

      Braathen, Martin; Rigby-Jones, Ann E.; Ræder, Johan; Spigset, Olav; Heier, Tom (Peer reviewed; Journal article, 2024)

    • Platelet transfusions in adult ICU patients with thrombocytopenia: A sub-study of the PLOT-ICU inception cohort study 

      Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry; Chawla, Sanjay; Castro, Pedro; Povoa, Pedro; Coelho, Luis; Metaxa, Victoria; Kochanek, Matthias; Liebregts, Tobias; Kander, Thomas; Sivula, Mirka; Andreasen, Jo Bønding; Nielsen, Lene Bjerregaard; Hvas, Christine Lodberg; Dufranc, Etienne; Canet, Emmanuel; Wright, Christopher John; Schmidt, Julien; Uhel, Fabrice; Missri, Louai; Krag, Mette; Cos Badia, Elisabet; Díaz-Lagares, Cándido; Menat, Sophie; Voiriot, Guillaume; Erikstrup Clausen, Niels; Lorentzen, Kristian; Kvåle, Reidar; Barratt-Due, Andreas; Hildebrandt, Thomas; Holten, Aleksander Rygh; Strand, Kristian; Bestle, Morten Heiberg; Klepstad, Pål; Vimpere, Damien; Paulino, Carolina; Lueck, Catherina; Juhl, Christian Svendsen; Costa, Carolina; Bådstøløkken, Per Martin; Lêdo, Lia Susana Aires; Møller, Morten Hylander; Russell, Lene (Peer reviewed; Journal article, 2024)
      Background Platelet transfusions are frequently used in the intensive care unit (ICU), but current practices including used product types, volumes, doses and effects are unknown. Study design and methods Sub-study ...

    • Postoperative quality and safety using Efficacy Safety Score (ESS) and a wireless patient monitoring system at the ward: A randomised controlled study 

      Skraastad, Erlend Johan; Borchgrevink, Petter Chr.; Nilsen, Tom Ivar Lund; Ræder, Johan (Journal article; Peer reviewed, 2019)
      Background: Postoperative pain, side‐effects and time to mobilisation are indica‐tors for the quality of postoperative recovery. The aim of this randomised controlled study was to investigate if efficacy safety score (ESS) ...

    • A survey of anaesthesia practices at all hospitals performing caesarean sections in Sierra Leone 

      Lonnee, Herman; Taule, Katinka; Sandvand, Johannes Knoph; Koroma, Michael M.; Dumbuya, Abubakar; Jusu, Kakpama S.K.; Shour, Mohamed A.; van Duinen, Aalke Johan (Peer reviewed; Journal article, 2020)
      Background Providing safe anaesthesia is essential when performing caesarean sections, one of the most commonly performed types of surgery. Anaesthesia-related causes of maternal mortality are generally considered ...

    • The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses 

      Skorpen, Frank; von Hofacker, Sebastian; Bjørngaard, Mads; Skogholt, Anne Heidi; Dale, Ola; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2016)
      BACKGROUND: Genetic variability contributes to variable clinical response to opioids. This study emerged from the observation of three Norwegian patients who showed no or extraordinary poor response to very high doses of ...

    • The trauma system and the patient - A national, regional and individual perspective 

      Uleberg, Oddvar (Peer reviewed; Journal article, 2019)
      Morbidity and mortality following traumatic injuries constitute a substantial global health challenge. This thesis aimed to describe the current challenges of trauma on a national, regional and individual level. Study 1 ...