Blar i Publikasjoner fra CRIStin - NTNU på tidsskrift "Nature Communications"

Viser treff 21-40 av 172

    • Automatic data-driven design and 3D printing of custom ocular prostheses 

      Reinhard, Johann; Urban, Philipp; Bell, Stephen; Carpenter, David; Sagoo, Mandeep S. (Journal article; Peer reviewed, 2024)
      Millions of people require custom ocular prostheses due to eye loss or congenital defects. The current fully manual manufacturing processes used by highly skilled ocularists are time-consuming with varying quality. Additive ...

    • Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses 

      Brumpton, Ben Michael; Sanderson, Eleanor; Heilbron, Karl; Hartwig, FP; Harrison, S; Vie, Gunnhild Åberge; Cho, Y; Howe, LD; Hughes, A; Boomsma, D; Havdahl, Alexandra; Hopper, J; Neale, M; Nivard, Michel G.; Pedersen, N; Reynolds, CA; Tucker-D, EM; Grotzinger, A; Howe, Laurence; Morris, Tim; Li, Shuai; Within-Family Consortium, The; 23andMe Research Team, The; Auton, A; Windmeijer, F; Chen, W-M; Bjørngaard, Johan Håkon; Hveem, Kristian; Willer, C; Evans, DM; Kaprio, J; Davey Smith, G; Åsvold, BO; Åsvold, Bjørn Olav; Hemani, G; Davies, Neil Martin (Peer reviewed; Journal article, 2020)
      Estimates from Mendelian randomization studies of unrelated individuals can be biased due to uncontrolled confounding from familial effects. Here we describe methods for within-family Mendelian randomization analyses and ...

    • Battery technology and recycling alone will not save the electric mobility transition from future cobalt shortages 

      Zeng, Anqi; Chen, Wu; Dalgas Rasmussen, Kasper; Zhu, Xuehong; Lundhaug, Maren Cathrine; Mueller, Daniel Beat; Tan, Juan; Keiding, Jakob K.; Liu, LiTao; Dai, Tao; Wang, Anjian; Liu, Gang (Peer reviewed; Journal article, 2022)
      In recent years, increasing attention has been given to the potential supply risks of critical battery materials, such as cobalt, for electric mobility transitions. While battery technology and recycling advancement are ...

    • Behavior-dependent directional tuning in the human visual-navigation network 

      Nau, Matthias (Peer reviewed; Journal article, 2020)
      The brain derives cognitive maps from sensory experience that guide memory formation and behavior. Despite extensive efforts, it still remains unclear how the underlying population activity unfolds during spatial navigation ...

    • Behavioral decomposition reveals rich encoding structure employed across neocortex in rats 

      Mimica, Bartul; Tombaz, Tuce; Battistin, Claudia; Fuglstad, Jingyi Guo; Dunn, Benjamin Adric; Whitlock, Jonathan Robert (Peer reviewed; Journal article, 2023)
      The cortical population code is pervaded by activity patterns evoked by movement, but it remains largely unknown how such signals relate to natural behavior or how they might support processing in sensory cortices where ...

    • Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism 

      Weber, Alain R.; Krawczyk, Claudia; Robertson, Adam Brian; Kusnierczyk, Anna; Vågbø, Cathrine Broberg; Schürmann, David; Klungland, Arne; Schär, Primo (Peer reviewed; Journal article, 2016)
      Cytosine methylation in CpG dinucleotides is an epigenetic DNA modification dynamically established and maintained by DNA methyltransferases and demethylases. Molecular mechanisms of active DNA demethylation began to surface ...

    • Bird populations most exposed to climate change are less sensitive to climatic variation 

      Bailey, Liam D.; van de Pol, Martijn; Adriaensen, Frank; Arct, Aneta; Barba, Emilio; Bellamy, Paul E.; Bonamour, Suzanne; Bouvier, Jean-Charles; Burgess, Malcolm D.; Charmantier, Anne; Cusimano, Camillo; Doligez, Blandine; Drobniak, Szymon M.; Dubiec, Anna; Eens, Marcel; Eeva, Tapio; Ferns, Peter N.; Goodenough, Anne E.; Hartley, Ian R.; Hinsley, Shelley A.; Ivankina, Elena; Juškaitis, Rimvydas; Kempenaers, Bart; Kerimov, Anvar B.; Lavigne, Claire; Leivits, Agu; Mainwaring, Mark C.; Matthysen, Erik; Nilsson, Jan-Åke; Orell, Markku; Rytkönen, Seppo; Senar, Juan Carlos; Sheldon, Ben C.; Sorace, Alberto; Stenning, Martyn J.; Török, János; van Oers, Kees; Vatka, Emma; Vriend, Stefan J.G.; Visser, Marcel E. (Peer reviewed; Journal article, 2022)
      The phenology of many species shows strong sensitivity to climate change; however, with few large scale intra-specific studies it is unclear how such sensitivity varies over a species’ range. We document large intra-specific ...

    • Bird tolerance to humans in open tropical ecosystems 

      Mikula, Peter; Tomášek, Oldřich; Romportl, Dušan; Aikins, Timothy K.; Avendaño, Jorge E.; Braimoh-Azaki, Bukola D A; Chaskda, Adams; Cresswell, Will; Cunningham, Susan J.; Dale, Svein; Favoretto, Gabriela R.; Floyd, Kelvin S.; Glover, Hayley; Grim, Tomáš; Henry, Dominic A. W.; Holmern, Tomas; Hromada, Martin; Iwajomo, Soladoye B.; Lilleyman, Amanda; Magige, Flora J.; Martin, Rowan O.; de A. Maximiano, Marina F.; Nana, Eric D.; Ncube, Emmanuel; Ndaimani, Henry; Nelson, Emma; van Niekerk, Johann H.; Pienaar, Carina; Piratelli, Augusto J.; Pistorius, Penny; Radkovic, Anna; Reynolds, Chevonne; Røskaft, Eivin; Shanungu, Griffin K.; Siqueira, Paulo R.; Tarakini, Tawanda; Tejeiro-Mahecha, Nattaly; Thompson, Michelle L.; Wamiti, Wanyoike; Wilson, Mark; Tye, Donovan R. C.; Tye, Nicholas D.; Vehtari, Aki; Tryjanowski, Piotr; Weston, Michael A.; Blumstein, Daniel T.; Albrecht, Tomáš (Peer reviewed; Journal article, 2023)
      Animal tolerance towards humans can be a key factor facilitating wildlife–human coexistence, yet traits predicting its direction and magnitude across tropical animals are poorly known. Using 10,249 observations for 842 ...

    • The blood proteome of imminent lung cancer diagnosis 

      Albanes, Demetrius; Alcala, Karine; Alcala, Nicolas; Amos, Christopher I.; Arslan, Alan A.; Bassett, Julie K.; Brennan, Paul; Cai, Qiuyin; Chen, Chu; Feng, Xiaoshuang; Freedman, Neal D.; Guida, Florence; Hung, Rayjean J.; Hveem, Kristian; Johansson, Mikael; Johansson, Mattias; Koh, Woon-Puay; Langhammer, Arnulf; Milne, Roger L.; Muller, David; Onwuka, Justina; Sørgjerd, Elin Pettersen; Robbins, Hilary A.; Sesso, Howard D.; Severi, Gianluca; Shu, Xiao-Ou; Sieri, Sabina; Smith-Byrne, Karl; Stevens, Victoria; Tinker, Lesley; Tjønneland, Anne; Visvanathan, Kala; Wang, Ying; Wang, Renwei; Weinstein, Stephanie; Yuan, Jian-Min; Zahed, Hana; Zhang, Xuehong; Zheng, Wei (Peer reviewed; Journal article, 2023)
      Identification of risk biomarkers may enhance early detection of smoking-related lung cancer. We measured between 392 and 1,162 proteins in blood samples drawn at most three years before diagnosis in 731 smoking-matched ...

    • Breast cancer quantitative proteome and proteogenomic landscape 

      Johansson, Henrik J.; Socciarelli, Fabio; Vacanti, Nathaniel M.; Haugen, Mads Haugland; Zhu, Yafeng; Siavelis, Ioannis; Fernandez-Woodbridge, Alejandro; Aure, Miriam Ragle; Sennblad, Bengt; Vesterlund, Mattias; Branca, Rui M.; Orre, Lukas M.; Huss, Mikael; Fredlund, Erik; Beraki, Else; Garred, Øystein; Boekel, Jorrit; Sauer, Torill; Zhao, Wei; Nord, Silje; Höglander, Elen K.; Jans, Daniel C.; Brismar, Hjalmar; Haukaas, Tonje Husby; Bathen, Tone Frost; Schlichting, Ellen; Naume, Bjørn; Luders, Torben; Borgen, Elin; Kristensen, Vessela N.; Russnes, Hege Elisabeth Giercksky; Lingjærde, Ole Christian; Mills, Gordon B.; Sahlberg, Kristine Kleivi; Børresen-Dale, Anne-Lise; Lehtiö, Janne (Journal article; Peer reviewed, 2019)
      In the preceding decades, molecular characterization has revolutionized breast cancer (BC) research and therapeutic approaches. Presented herein, an unbiased analysis of breast tumor proteomes, inclusive of 9995 proteins ...

    • Carbon hollow fiber membranes for a molecular sieve with precise-cutoff ultramicropores for superior hydrogen separation 

      Lei, Linfeng; Pan, Fengjiao; Lindbråthen, Arne; Zhang, Xiangping; Hillestad, Magne; Nie, Yi; Bai, Lu; He, Xuezhong; Guiver, Michael D. (Peer reviewed; Journal article, 2021)
      Carbon molecular sieve (CMS) membranes with rigid and uniform pore structures are ideal candidates for high temperature- and pressure-demanded separations, such as hydrogen purification from the steam methane reforming ...

    • The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization 

      Korologou-Linden, Roxanna; Bhatta, Laxmi; Brumpton, Ben Michael; Howe, Laura D.; Millard, Louise A. C.; Kolaric, Katarina; Ben-Shlomo, Yoav; Williams, Dylan M.; Smith, George Davey; Anderson, Emma L.; Stergiakouli, Evie; Davies, Neil Martin (Peer reviewed; Journal article, 2022)
      Alzheimer’s disease (AD) has no proven causal and modifiable risk factors, or effective interventions. We report a phenome-wide association study (PheWAS) of genetic liability for AD in 334,968 participants of the UK Biobank ...

    • Climatic conditions are weak predictors of asylum migration 

      Schutte, Sebastian; Nordkvelle, Jonas; Carling, Jørgen; Buhaug, Halvard (Journal article; Peer reviewed, 2021)

    • Clocked dynamics in artificial spin ice 

      Jensen, Johannes Høydahl; Strømberg, Anders; Breivik, Ida; Penty, Arthur George; Nino, Miguel Angel; Khaliq, Muhammad Waqas; Foerster, Michael; Tufte, Gunnar; Folven, Erik (Peer reviewed; Journal article, 2024)
      Artificial spin ice (ASI) are nanomagnetic metamaterials with a wide range of emergent properties. Through local interactions, the magnetization of the nanomagnets self-organize into extended magnetic domains. However, ...

    • Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance 

      Pietilä, Elina A.; Gonzalez-Molina, Jordi.; Moyano-Galceran, Lidia; Jamalzadeh, Sanaz; Zhang, Kaiyang; Lehtinen, Laura; Turunen, S Pauliina; Martins, Tomás A; Gultekin, Okan; Lamminen, Tarja; Kaipio, Katja; Joneborg, Ulrika; Hynninen, Johanna; Hietanen, Sakara; Grénman, Seija; Lehtonen, Rainer; Hautaniemi, Sampsa; Carpén, Olli; Carlson, Joseph W.; Lehti, Kaisa (Peer reviewed; Journal article, 2021)
      Due to its dynamic nature, the evolution of cancer cell-extracellular matrix (ECM) crosstalk, critically affecting metastasis and treatment resistance, remains elusive. Our results show that platinum-chemotherapy itself ...

    • Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits 

      Gilly, Arthur; Suveges, Daniel; Kuchenbaecker, Karoline; Pollard, Martin; Southam, Lorraine; Hatzikotoulas, Konstantinos; Farmaki, Aliki-Eleni; Bjørnland, Thea; Waples, Ryan; Appel, Emil; Casalone, Elisabetta; Melloni, Giorgio; Kilian, Britt; Rayner, William; Ntalla, Ioanna; Kundu, Kousik; Walter, Klaudia; Danesh, John; Butterworth, Adam; Barroso, Ines; Tsafantakis, Emmanouil; Dedoussis, George; Moltke, Ida; Zeggini, Eleftheria (Journal article; Peer reviewed, 2018)
      The role of rare variants in complex traits remains uncharted. Here, we conduct deep whole genome sequencing of 1457 individuals from an isolated population, and test for rare variant burdens across six cardiometabolic ...

    • Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores 

      de Rojas, Itziar; Moreno-Grau, Sonia; Tesi, Niccolo; Grenier-Boley, Benjamin; Andrade, Victor; Jansen, Iris E.; Rongve, Arvid; Aarsland, Dag; Selbæk, Geir; Saltvedt, Ingvild; Sando, Sigrid Botne; Djurovic, Srdjan; Andreassen, Ole; Pedersen, Nancy L.; Stringa, Najada; Zettergren, Anna; Hernández, Isabel; Montrreal, Laura; Antunez, Carmen; Antonell, Anna; Tankard, Rick; Bis, Joshua C.; Sims, Rebecca; Bellenguez, Celine; Quintela, Inés; González-Pérez, Antonio; Calero, Miguel; Franco-Macias, Emilio; Macias, Juan; Blesa, Rafael; Cervera-Carles, Laura; Menendez-Gonzalez, Manuel; Frank-Garcia, Ana; Royo, José Luis; Moreno, Fermin; Vilas, Raquel Huerto; Baquero, Miquel; Diez-Fairen, Monica; Lage, Carmen; García-Madrona, Sebastian; Garcia-Gonzalez, Pablo; Alarcón-Martín, Emilio; Valero, Sergi; Sotolongo-Grau, Oscar; Ullgren, Abbe; Naj, Adam C.; Lemstra, Afina W.; Benaque, Alba; Perez-Cordon, Alba; Benussi, Alberto; Rabano, Alberto (Peer reviewed; Journal article, 2021)
      Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical ...

    • Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen 

      Kuiper, Martin; Lægreid, Astrid; Flobak, Åsmund; Thommesen, Liv; Team, Dream (Journal article; Peer reviewed, 2019)
      The effectiveness of most cancer targeted therapies is short-lived. Tumors often developresistance that might be overcome with drug combinations. However, the number of possiblecombinations is vast, necessitating data-driven ...

    • Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism 

      Arbore, Giuseppina; West, Erin; Rahman, Jubayer; Le Friec, Gaelle; Niyonzima, Nathalie; Mehdi, Pirooznia; Ilker, Tunc; Polychronis, Pavlidis; Nicholas, Powell; Li, Yuesheng; Liu, Poching; Servais, Aude; Couzi, Lionel; Fremeaux-Bacchi, Veronique; Placais, Leo; Ferraro, Alastair; Walsh, Patrick R.; Kavanagh, David; Afzali, Behdad; Lavender, Paul; Lachmann, Helen J.; Kemper, Claudia (Journal article; Peer reviewed, 2018)
      The induction of human CD4+ Th1 cells requires autocrine stimulation of the complement receptor CD46 in direct crosstalk with a CD4+ T cell-intrinsic NLRP3 inflammasome. However, it is unclear whether human cytotoxic CD8+ ...

    • The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants 

      Rio-Machin, Ana; Villiamy, Tom; Hug, Nele; Walne, Amanda; Tawana, Kiran; Cardoso, Shirleny; Ellison, Alicia; Pontikos, Nikolas; Wang, Jun; Tummala, Hemanth; Al Seraihi, Ahad Fahad H.; Alnajar, Jenna; Bewicke-Copley, Findlay; Barnett, Michael; Armes, Hannah; Bloor, Adrian; Bödör, Csabo; Bowen, David; Fenaux, Pierre; Green, Andrew; Hallahan, Andrew; Hjorth-Hansen, Henrik; Hossein, Upal; Killick, Sally; Lawson, Sarah; Layton, Mark; Male, Alison M.; Marsh, Judith; Mehta, Priyanka; Mous, Rogier; Nomdedéu, Josep F.; Owen, Carolyn; Pavlu, Jiri; Payne, Elspeth; Protheroe, Rachel E.; Preudhomme, Claude; Pujol-Moix, Nuria; Renneville, Aline; Russell, Nigel; Saggar, Anand; Sciuccati, Gabriela; Taussig, David; Toze, Cynthia; Uyttebroeck, Anne; Vandenberghe, Peter; Schlegelberger, Brigitte; Ripperger, Tim; Steinemann, Doris; Wu, John; Mason, Joanne; Page, Paula; Akiki, Susanna; Reay, Kim; Cavenagh, Jamie D.; Plagnol, Vincent; Caceres, Javier F.; Fitzgibbon, Jude; Dokal, Inderjeet (Peer reviewed; Journal article, 2020)
      The inclusion of familial myeloid malignancies as a separate disease entity in the revised WHO classification has renewed efforts to improve the recognition and management of this group of at risk individuals. Here we ...