• Cancer-induced muscle atrophy is determined by intrinsic muscle oxidative capacity 

      Alves, Christiano R. R.; Eichelberger, Eric J.; das Neves, Willian; Ribeiro, Márcio A. C.; Bechara, Luiz R.G.; Voltarelli, Vanessa A.; de Almeida, Ney R.; Hagen, Lars; Sharma, Animesh; Ferreira, Julio C. B.; Swoboda, Kathryn J.; Slupphaug, Geir; Brum, Patricia C. (Peer reviewed; Journal article, 2021)
      We tested the hypothesis that cancer cachexia progression would induce oxidative post-translational modifications (Ox-PTMs) associated with skeletal muscle wasting, with different responses in muscles with the prevalence ...
    • Demyelinating polyneuropathy in goats lacking prion protein 

      Skedsmo, Fredrik Strebel; Malachin, Giulia; Våge, Dag Inge; Hammervold, Mie Marie; Salvesen, Øyvind; Ersdal, Cecilie; Ranheim, Birgit; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Bruheim, Per; Jäderlund, Karin Hultin; Matiasek, Kaspar; Espenes, Arild; Tranulis, Michael A. (Journal article; Peer reviewed, 2019)
      Studies in mice with ablation of Prnp, the gene that encodes the cellular prion protein (PrPC), have led to the hypothesis that PrPC is important for peripheral nerve myelin maintenance. Here, we have used a nontransgenic ...
    • Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia A comparison among participants between 2 and 53 years 

      Hope, Sigrun; Nærland, Terje; Høyland, Anne Lise; Torske, Tonje; Malt, Eva; Abrahamsen, Tore G; Nerhus, Mari; Wedervang-Resell, Kirsten; Lonning, Vera Louise Hiorth; Johannessen, Jarle; Steen, Nils Eiel; Agartz, Ingrid; Stenberg, Nina; Hundhausen, Thomas Eckhard; Mørkrid, Lars; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2020)
      Recent studies suggest that both high and low levels of vitamin B12 (vitB12) may have negative health impacts. We measured VitB12 in patients with the Neurodevelopmental disorders (ND) (n = 222), comprised of Autism Spectrum ...
    • Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma 

      Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved; Andreassen, Trygve; Misund, Kristine; Slørdahl, Tobias Schmidt; Rø, Torstein Baade; Sponaas, Anne-Marit; Moestue, Siver Andreas; Bruheim, Per; Børset, Magne (Peer reviewed; Journal article, 2021)
      Cancer cells often depend on microenvironment signals from molecules such as cytokines for proliferation and metabolic adaptations. PRL‐3, a cytokine‐induced oncogenic phosphatase, is highly expressed in multiple myeloma ...