dc.contributor.author | Karlsen, Håvard Rudi | |
dc.contributor.author | Saksvik-Lehouillier, Ingvild | |
dc.contributor.author | Stone, Katie L. | |
dc.contributor.author | Schernhammer, Eva | |
dc.contributor.author | Yaffe, Kristine | |
dc.contributor.author | Langvik, Eva | |
dc.date.accessioned | 2021-02-17T10:27:39Z | |
dc.date.available | 2021-02-17T10:27:39Z | |
dc.date.created | 2020-07-21T10:35:34Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Psychology and Health. 2020, 36 (2), 148-163. | en_US |
dc.identifier.issn | 0887-0446 | |
dc.identifier.uri | https://hdl.handle.net/11250/2728632 | |
dc.description.abstract | Anxiety and depression have been linked to increased risk of cardiovascular disease (CVD). Whether anxiety is a risk factor independent from depression, and if associations are limited to specific CVD outcomes remains unclear. Design: Participants (N = 3135) of the prospective Osteoporotic Fracturs in Men Sleep ancillary study were community-dwelling men (age ≥ 65) living in the US. Main outcome measures: The Goldberg Anxiety and Depression Scales, coronary heart disease (CHD) and cerebrovascular disease (CER). We used Cox proportional hazards models to calculate adjusted hazard ratios and 95% confidence intervals. Results: During 12 years of follow-up, we accrued 612 cases of CHD and 291 cases of CER (incident or repeat-event). Overall, we observed no association between anxiety or depression and CER. Anxiety was significantly associated with CHD, but this effect was attenuated after controlling for depression and covariates. Depression was significantly associated with CHD after similar adjustments. For men without prior history of CVD, neither anxiety nor depression were associated with incident CHD. Conclusions: Anxiety was not a significant independent predictor of CHD or CER, suggesting that previous findings of anxiety as a risk factor of CVD might be attributed to failure to control for the effect of depression. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Informa UK Limited, trading as Taylor & Francis Group | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | Anxiety as a risk factor for cardiovascular disease independent of depression: A prospective examination of community-dwelling men (The MrOS study) | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.source.pagenumber | 148-163 | en_US |
dc.source.volume | 36 | en_US |
dc.source.journal | Psychology and Health | en_US |
dc.source.issue | 2 | en_US |
dc.identifier.doi | 10.1080/08870446.2020.1779273 | |
dc.identifier.cristin | 1819988 | |
dc.description.localcode | © 2020 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |