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AI-driven attenuation correction for brain PET/MRI: Clinical evaluation of a dementia cohort and importance of the training group size
(Peer reviewed; Journal article, 2020)Introduction Robust and reliable attenuation correction (AC) is a prerequisite for accurate quantification of activity concentration. In combined PET/MRI, AC is challenged by the lack of bone signal in the MRI from which ... -
Atypical brain structure mediates reduced IQ in young adults born preterm with very low birth weight
(Peer reviewed; Journal article, 2022)Preterm birth with very low birth weight (VLBW) confers heightened risk for perinatal brain injury and long-term cognitive deficits, including a reduction in IQ of up to one standard deviation. Persisting gray and white ... -
Longitudinal study of the effect of a 5-year exercise intervention on structural brain complexity in older adults. A Generation 100 substudy
(Peer reviewed; Journal article, 2022)Physical inactivity has been identified as an important risk factor for dementia. High levels of cardiorespiratory fitness (CRF) have been shown to reduce the risk of dementia. However, the mechanism by which exercise ... -
Neural networks for parameter estimation in microstructural MRI: application to a diffusion-relaxation model of white matter
(Peer reviewed; Journal article, 2021)Specific features of white matter microstructure can be investigated by using biophysical models to interpret relaxation-diffusion MRI brain data. Although more intricate models have the potential to reveal more details ...