• Associations between post-stroke motor and cognitive function: a cross-sectional study 

      Einstad, Marte Stine; Saltvedt, Ingvild; Lydersen, Stian; Ursin, Marie Helene; Munthe-Kaas, Ragnhild; Ihle-Hansen, Hege; Askim, Torunn; Beyer, Mona K.; Næss, Halvor; Seljeseth, Yngve Müller; Ellekjær, Hanne; Thingstad, Pernille (Peer reviewed; Journal article, 2021)
      Background Motor and cognitive impairments are frequently observed following stroke, but are often managed as distinct entities, and there is little evidence regarding how they are related. The aim of this study was to ...
    • Cerebrospinal fluid sTREM2 in Alzheimer’s disease: comparisons between clinical presentation and AT classification 

      Knapskog, Anne Brita; Henjum, Kristi; Idland, Ane-Victoria; Eldholm, Rannveig Sakshaug; Persson, Karin Ester Torun; Saltvedt, Ingvild; Watne, Leiv; Engedal, Knut; Nilsson, Lars N.G. (Peer reviewed; Journal article, 2020)
      Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune receptor expressed by microglia. Its cleaved fragments, soluble TREM2 (sTREM2), can be measured in the cerebrospinal fluid (CSF). Previous studies ...
    • Client, caregiver, volunteer, and therapist views on a voluntary supported group exercise programme for older adults with dementia 

      Taraldsen, Kristin; Boulton, Elisabeth; Helbostad, Jorunn L.; Saltvedt, Ingvild; Granbo, Randi (Peer reviewed; Journal article, 2020)
      Background: Existing group exercise programmes, or other services offered to maintain physical activity levels, are typically not developed specifically for older adults with dementia. The aim of this study was to gain ...
    • Clinically accessible neuroimaging predictors of post-stroke neurocognitive disorder: a prospective observational study 

      SCHELLHORN, TILL; Aamodt, Eva Birgitte; Lydersen, Stian; Aam, Stina; Wyller, Torgeir Bruun; Saltvedt, Ingvild; Beyer, Mona Kristiansen (Peer reviewed; Journal article, 2021)
      Background Neurocognitive disorder (NCD) is common in stroke survivors. We aimed to identify clinically accessible imaging markers of stroke and chronic pathology that are associated with early post-stroke NCD. Methods We ...
    • Delirium og kognitiv svikt blant eldre i norske akuttmottak 

      Evensen, Sigurd; Saltvedt, Ingvild; Ranhoff, Anette Hylen; Myrstad, Marius; Myrstad, Christian; Mellingsæter, Marte; Wang-Hansen, Marte Sofie; Neerland, Bjørn Erik (Journal article; Peer reviewed, 2019)
      BAKGRUNN Delirium er vanlig og underdiagnostisert blant pasienter på sykehus og er assosiert med komplikasjoner, økt dødelighet, demensutvikling og behov for sykehjemsplass. Kognitiv svikt av andre årsaker er også vanlig ...
    • The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity 

      Evensen, Sigurd; Hylen Ranhoff, Anette; Lydersen, Stian; Saltvedt, Ingvild (Peer reviewed; Journal article, 2021)
      Purpose Delirium is common and associated with poor outcomes, partly due to underdetection. We investigated if the delirium screening tool 4 A’s test (4AT) score predicts 1 year mortality and explored the sensitivity and ...
    • Development and delivery of patient treatment in the Trondheim Hip Fracture Trial. A new geriatric in-hospital pathway for elderly patients with hip fracture 

      Saltvedt, Ingvild; Prestmo, Anders; Einarsen, Elin Kristin; Johnsen, Lars Gunnar; Helbostad, Jorunn L.; Sletvold, Olav (Journal article; Peer reviewed, 2012)
      Background Hip fractures are common among frail elderly persons and often have serious consequences on function, mobility and mortality. Traditional treatment of these patients is performed in orthopedic departments without ...
    • Effect of in-hospital comprehensive geriatric assessment (CGA) in older people with hip fracture. The protocol of the Trondheim Hip Fracture Trial 

      Sletvold, Olav; Helbostad, Jorunn L.; Thingstad, Pernille; Taraldsen, Kristin; Prestmo, Anders; Lamb, SE; Aamodt, Arild; Johnsen, Roar; Magnussen, Jon; Saltvedt, Ingvild (Journal article; Peer reviewed, 2011)
      Background Hip fractures in older people are associated with high morbidity, mortality, disability and reduction in quality of life. Traditionally people with hip fracture are cared for in orthopaedic departments without ...
    • Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease 

      DeMichele-Sweet, Mary Ann A.; Klei, Lambertus; Creese, Byron; Harwood, Janet C.; Weamer, Elise A.; McClain, Lora; Sims, Rebekka; Hernández, Isabel; Moreno-Grau, Sonia; Tárraga, Lluís; Boada, Mercè; Alarcón-Martín, Emilio; Valero, Sergi; Liu, Yushi; Hooli, Basavaraj; Aarsland, Dag; Selbæk, Geir; Bergh, Sverre; Rongve, Arvid; Saltvedt, Ingvild; Skjellegrind, Håvard; Engdahl, Bo Lars; Stordal, Eystein; Andreassen, Ole Andreas; Djurovic, Srdjan; Athanasiu, Lavinia; Seripa, Davide; Borroni, Barbara; Albani, Diego; Forloni, Gianluigi; Mecocci, Patrizia; Seretti, Alessandro; De Ronchi, Diana; Politis, Antonis; Williams, Julie; Mayeux, Richard; Foroud, Tatiana; Ruiz, Agustin; Ballard, Clive; Holmans, Peter; Lopez, Oscar L.; Kamboh, M. Ilyas; Devlin, Bernie; Sweet, Robert A. (Peer reviewed; Journal article, 2021)
      Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzheimer disease (AD with psychosis, AD + P). AD + P affects ~50% of individuals with AD, identifies a subgroup with poor ...
    • A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease 

      Wightman, Douglas P.; Jansen, Iris E.; Savage, Jeanne E.; Shadrin, Alexey; Bahrami, Shahram; Holland, Dominic; Rongve, Arvid; Børte, Sigrid; Winsvold, Bendik K S; Drange, Ole Kristian; Martinsen, Amy E.; Skogholt, Anne Heidi; Willer, Cristen; Bråthen, Geir; Bosnes, Ingunn; Nielsen, Jonas Bille; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Meisingset, Tore Wergeland; Zhou, Wei; Proitsi, Petroula; Hodges, Angela; Dobson, Richard; Velayudhan, Latha; Sealock, Julia; Davis, Lea K.; Pedersen, Nancy L.; Reynolds, Chandra A.; Karlsson, Ida K.; Magnusson, Sigurdur; Stefansson, Hreinn; Thordardottir, Steinunn; Jónsson, Pálmi V.; Snædal, Jon; Zettergren, Anna; Skoog, Ingmar; Kern, Silke; Waern, Margda; Zetterberg, Henrik; Blennow, Kaj; Stordal, Eystein; Hveem, Kristian; Zwart, John Anker Henrik; Athanasiu, Lavinia; Selnes, Per; Saltvedt, Ingvild; Sando, Sigrid Botne; Ulstein, Ingun; Djurovic, Srdjan; Fladby, Tormod; Aarsland, Dag; Selbæk, Geir; Ripke, Stephan; Stefánsson, Kári; Andreassen, Ole; Posthuma, Danielle (Journal article; Peer reviewed, 2021)
      Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying Alzheimer’s disease have been identified. ...
    • Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk 

      Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Peer reviewed, 2019)
      Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ...
    • A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease 

      Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Peer reviewed; Journal article, 2020)
      Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...
    • The Human Brain Representation of Odor Identification in Amnestic Mild Cognitive Impairment and Alzheimer's Dementia of Mild Degree 

      Kjelvik, Grete; Evensmoen, Hallvard Røe; Hummel, Thomas; Engedal, Knut; Selbæk, Geir; Saltvedt, Ingvild; Håberg, Asta (Peer reviewed; Journal article, 2020)
      Background: Odor identification (OI) ability is a suggested early biomarker of Alzheimer’s disease. In this study, we investigated brain activity within the brain’s olfactory network associated with OI in patients with ...
    • Impact of different methods defining post-stroke neurocognitive disorder: The Nor-COAST study 

      Munthe-Kaas, Ragnhild; Aam, Stina; Ihle-Hansen, Hege; Lydersen, Stian; Knapskog, Anne Brita; Wyller, Torgeir Bruun; Fure, Brynjar; Thingstad, Pernille; Askim, Torunn; Beyer, Mona K.; Næss, Halvor; Seljeseth, Yngve Müller; Ellekjær, Hanne; Pendlebury, Sarah T.; Saltvedt, Ingvild (Peer reviewed; Journal article, 2020)
      Introduction Post‐stroke neurocognitive disorder (NCD) is common; prevalence varies between studies, partially related to lack of consensus on how to identify cases. The aim was to compare the prevalence of post‐stroke ...
    • The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study 

      Aam, Stina; Gynnild, Mari Nordbø; Munthe-Kaas, Ragnhild; Saltvedt, Ingvild; Lydersen, Stian; Knapskog, Anne Brita; Ihle-Hansen, Hege; Ellekjær, Hanne; Eldholm, Rannveig Sakshaug; Fure, Brynjar (Peer reviewed; Journal article, 2021)
      Introduction: Post-stroke cognitive impairment (PSCI) is common, but evidence on the impact of vascular risk factors is lacking. We explored the association between pre-stroke vascular risk factors and PSCI and studied the ...
    • Interdisciplinary care of hip fractures: Orthogeriatric models, alternative models, interdisciplinary teamwork 

      Ranhoff, Anette Hylen; Saltvedt, Ingvild; Frihagen, Frede Jon; Ræder, Johan; Maini, Sameer; Sletvold, Olav (Journal article; Peer reviewed, 2019)
      Hip fractures are common among older people, and the prognosis is serious in terms of mobility, independence in daily life activities, and cognition, with 42% of patients never achieving the same function as before the ...
    • The long-term effect of being treated in a geriatric ward compared to an orthopaedic ward on six measures of free-living physical behavior 4 and 12 months after a hip fracture – a randomised controlled trial. 

      Taraldsen, Kristin; Thingstad, Pernille; Sletvold, Olav; Saltvedt, Ingvild; Lydersen, Stian; Granat, Malcolm H.; Chastin, Sebastien; Helbostad, Jorunn L. (Peer reviewed; Journal article, 2015)
      Background This study is part of the Trondheim Hip Fracture Trial, where we compared free-living physical behavior in daily life 4 and 12 months following hip surgery for patients managed with comprehensive geriatric ...
    • Moderately increased albuminuria, chronic kidney disease and incident dementia: the HUNT study 

      Gabin, Jessica Mira; Romundstad, Solfrid; Saltvedt, Ingvild; Holmen, Jostein (Journal article; Peer reviewed, 2019)
      Background Epidemiologic studies has shown an association of albuminuria and low estimated glomerular filtration rate (eGFR) with dementia, but the findings are inconsistent. This study examines the association between ...
    • Modifiable factors affecting older patients' quality of life and physical function during cancer treatment 

      Kirkhus, Lene; Harneshaug, Magnus; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Bergh, Sverre; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Kirkevold, Øyvind; Borza, Tom; Saltvedt, Ingvild; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)
      Background Maintaining physical function and quality of life (QoL) are prioritized outcomes among older adults. We aimed to identify potentially modifiable factors affecting older patients' physical function and QoL ...
    • Motor activity across delirium motor subtypes in geriatric patients assessed using body-worn sensors: a Norwegian cross-sectional study 

      Evensen, Sigurd Storhaug; Bourke, Alan; Lydersen, Stian; Sletvold, Olav; Saltvedt, Ingvild; Wyller, Torgeir Bruun; Taraldsen, Kristin (Journal article; Peer reviewed, 2019)
      Objectives It remains unclear if geriatric patients with different delirium motor subtypes express different levels of motor activity. Thus, we used two accelerometer-based devices to simultaneously measure upright activity ...