Blar i St. Olavs hospital på forfatter "Olsen, Lene Christin"
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Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation
Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Olsen, Lene Christin; Chawla, Konika; Aas, Per Arne; Sætrom, Pål (Peer reviewed; Journal article, 2021)Proper regulation of the cell cycle is necessary for normal growth and development of all organisms. Conversely, altered cell cycle regulation often underlies proliferative diseases such as cancer. Long non-coding RNAs ... -
MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari (Peer reviewed; Journal article, 2021)MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as central regulators of gene expression and powerful biomarkers of disease. Much is yet unknown about their role in psoriasis pathology. To globally characterize ... -
Mortality and neurodevelopmental outcome after invasive group B streptococcal infection in infants
Mynarek, Maren; Vik, Torstein; Andersen, Guro Lillemoen; Brigtsen, Anne Karin; Hollung, Sandra Julsen; Larose, Tricia L; Lydersen, Stian; Olsen, Lene Christin; Strøm, Marianne; Afset, Jan Egil (Peer reviewed; Journal article, 2023)Aim: To assess case fatality rate (CFR), infant mortality, and long-term neurodevelopmental disorders (NDDs) after invasive group B streptococcal (GBS; Streptococcus agalactiae) infection in infants. Method: Children born ... -
Single Cell Transcriptomic and Chromatin Profiles Suggest Layer Vb Is the Only Layer With Shared Excitatory Cell Types in the Medial and Lateral Entorhinal Cortex
Blankvoort, Stefan; Olsen, Lene Christin; Kentros, Clifford (Peer reviewed; Journal article, 2022)All brain functionality arises from the activity in neural circuits in different anatomical regions. These regions contain different circuits comprising unique cell types. An integral part to understanding neural circuits ...