• Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients with Recurrent Glioblastoma: A Randomized Clinical Trial 

      Werlenius, Katja; Kinhult, Sara; Solheim, Tora S; Magelssen, Henriette; Löfgren, David; Mudaisi, Munila; Hylin, Sofia; Bartek, Jiri; Strandéus, Michael; Lindskog, Magnus; Rashid, Havyan Bahroz; Carstam, Louise; Gulati, Sasha; Solheim, Ole Skeidsvoll; Salvesen, Øyvind Olav; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Importance Disulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma. Objective To evaluate the efficacy and safety of ...
    • Investigating survival, quality of life and cognition in PROton versus photon therapy for IDH- mutated diffuse grade 2 and 3 GLIOmas (PRO-GLIO): a randomised controlled trial in Norway and Sweden 

      Heggebø, Liv Cathrine; Borgen, Ida Maria Henriksen; Rylander, Hillevi; Kiserud, Cecilie E.; Nordenmark, Tonje Kristin Haug; Hellebust, Taran Annette Paulsen; Evensen, Morten Egeberg; Gustavsson, Magnus; Ramberg, Christina; Sprauten, Mette; Magelssen, Henriette; Blakstad, Hanne; Moorthy, Janani; Andersson, Karin; Raunert, Ingela; Henry, Thomas; Moe, Cecilie; Granlund, Carin; Goplen, Dorota; Brekke, Jorunn; Johannessen, Tor-Christian Aase; Solheim, Tora S; Marienhagen, Kirsten; Humberset, Øyvind; Bergström, Per; Agrup, Måns; Dahl, Ludvig; Gubanski, Michael; Gojon, Helene; Brahme, Carl-Johan; Rydén, Isabelle; Jakola, Asgeir Store; Vik-Mo, Einar O.; Lie, Hanne Cathrine; Asphaug, Lars; Hervani, Maziar; Kristensen, Ingrid; Rüegg, Corina Silvia; Olsen, Inge Christoffer; Ledal, Rolf J; Degsell, Eskil; Werlenius, Katja; Blomstrand, Malin; Brandal, Petter (Peer reviewed; Journal article, 2023)
      Abstract Introduction The use of proton therapy increases globally despite a lack of randomised controlled trials demonstrating its efficacy and safety. Proton therapy enables sparing of non-neoplastic tissue from ...
    • Normal tissue complication probability models in plan evaluation of children with brain tumors referred to proton therapy 

      Stokkevåg, Camilla Hanquist; Indelicato, Daniel J.; Herfarth, Klaus; Magelssen, Henriette; Evensen, Morten Egeberg; Ugland, Maren; Nordberg, Terje; Nystad, Tove Anita; Hægeland, Camilla; Alsaker, Mirjam Delange; Ulven, Kjetil; Dale, Jon Espen; Engeseth, Grete May; Boer, Camilla G.; Toussaint, Laura; Kornerup, Josefine Frida Margareta Ståhl; Pettersen, Helge Egil Seime; Brydøy, Marianne; Brandal, Petter; Muren, Ludvig Paul (Peer reviewed; Journal article, 2019)
      Background: Children with brain tumors undergoing radiotherapy are at particular risk of radiation-induced morbidity and are therefore routinely considered for proton therapy (PT) to reduce the dose to healthy tissues. The ...