• Assessing short-term risk of ischemic stroke in relation to all prescribed medications 

      Janszky, Imre; Vardaxis, Ioannis; Lindqvist, Bo Henry; Horn, Jens; Brumpton, Ben Michael; Strand, Linn Beate; Bakken, Inger Johanne Landsjøåsen; Alsnes, Ingvild Vatten; Romundstad, Pål Richard; Ljung, Rickard; Mukamal, Kenneth J.; Sen, Abhijit (Peer reviewed; Journal article, 2021)
      We examined the short-term risk of stroke associated with drugs prescribed in Norway or Sweden in a comprehensive, hypothesis-free manner using comprehensive nation-wide data. We identified 27,680 and 92,561 cases with a ...
    • Asthma, asthma control and risk of ischemic stroke: The HUNT study 

      Cepelis, Aivaras; Brumpton, Ben Michael; Laugsand, Lars Erik; Langhammer, Arnulf; Janszky, Imre; Strand, Linn B (Journal article; Peer reviewed, 2019)
      Background: Asthma, a chronic inflammatory airway disease, shares common pathophysiological mechanisms with ischemic stroke. The aim of the study is to assess the association between asthma, levels of asthma control and ...
    • Biological and Clinical Insights From Genetics of Insomnia Symptoms 

      Lane, Jacqueline M.; Jones, Samuel E.; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Brumpton, Ben Michael; Zwart, John-Anker; Nielsen, Jonas Bille; Winswold, Bendik; Willer, Cristen J; Janszky, Imre; Johnsen, Marianne Bakke; Wood, Andrew R.; Strand, Linn B.; Bowden, Jack; Song, Yanwei; Patel, Krunal; Anderson, Simon G.; Beaumont, Robin N.; Bechtold, David A.; Cade, Brian E.; Kathiresan, Sekar; Little, Max A.; Loudon, Andrew S.; Purcell, Shaun; Richmond, Rebecca C.; Schormair, Barbara; Tyrrell, Jessica; Winkelmann, Juliane; Zhao, Cheng; Redline, Susan; Spiegelhalder, Kai; Kyle, Simon D.; Frayling, Timothy M.; Lawlor, Deborah A.; Rutter, Martin K.; Weedon, Michael N.; Saxena, Richa (Journal article; Peer reviewed, 2019)
      Insomnia is a common disorder linked with adverse long-term medical and psychiatric outcomes. The underlying pathophysiological processes and causal relationships of insomnia with disease are poorly understood. Here we ...
    • Epilepsy is overrepresented among young people who died from COVID-19: Analysis of nationwide mortality data in Hungary 

      Horwáth, Réka A.; Sütö, Zsófia; Cséke, Balázs; Schranz, Dániel; Darnai, Gergely; Kovács, Norbert; Janszky, Imre; Janszky, József (Peer reviewed; Journal article, 2021)
      Background : Studies examining epilepsy as a COVID-related death risk have come to conflicting conclusions. Our aim was to assess the prevalence of epilepsy among COVID-related deaths in Hungary. Methods Each COVID-19 ...
    • High ward occupancy, bedspacing, and 60 day mortality for patients with myocardial infarction, stroke, and heart failure 

      Asheim, Andreas; Nilsen, Sara Marie; Aam, Stina; Anthun, Kjartan Sarheim; Carlsen, Fredrik; Janszky, Imre; Vatten, Lars Johan; Bjørngaard, Johan Håkon (Journal article; Peer reviewed, 2022)
      Abstract Aims To study the consequences of crowded wards among patients with cardiovascular disease. Methods and results This is a cohort study among 201 801 patients with 258 807 admissions who were acutely admitted for ...
    • Influenza vaccination and risk for cardiovascular events: a nationwide self-controlled case series study 

      Sen, Abhijit; Bakken, Inger Johanne Landsjøåsen; Govatsmark, Ragna Elise Støre; Varmdal, Torunn; Bønaa, Kaare Harald; Mukamal, Kenneth Jay; Håberg, Siri Eldevik; Janszky, Imre (Peer reviewed; Journal article, 2021)
      Background US and European guidelines diverge on whether to vaccinate adults who are not at high risk for cardiovascular events against influenza. Here, we investigated the associations between influenza vaccination and ...
    • Risk for Acute Myocardial Infarction After Ophthalmologic Procedures 

      Sen, Abhijit; Gemes, Katalin; Stålhammar, Gustav; Svensén, Christer; Tornvall, Per; Jonsson, Magnus; Varmdal, Torunn; Endreseth, Birger Henning; Janszky, Imre; Møller, Jette (Peer reviewed; Journal article, 2022)
      Background: Preoperative cardiovascular evaluations are frequently done before ambulatory ophthalmologic procedures. However, whether these procedures can trigger an acute myocardial infarction (AMI) is unknown. Obje ...
    • Systematic assessment of prescribed medications and short-term risk of myocardial infarction - a pharmacopeia-wide association study from Norway and Sweden 

      Sen, Abhijit; Vardaxis, Ioannis; Lindqvist, Bo Henry; Brumpton, Ben Michael; Strand, Linn B; Bakken, Inger Johanne Landsjøåsen; Vatten, Lars Johan; Romundstad, Pål Richard; Ljung, Rickard; Mukamal, Kenneth Jay; Janszky, Imre (Journal article; Peer reviewed, 2019)
      Wholesale, unbiased assessment of Scandinavian electronic health-care databases offer a unique opportunity to reveal potentially important undiscovered drug side effects. We examined the short-term risk of acute myocardial ...
    • Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition 

      Brumpton, Ben Michael; Fritsche, Lars; Zheng, Jie; Nielsen, Jonas Bille; Mannila, Maria Nastase; Surakka, Ida; Rasheed, Humaira; Vie, Gunnhild Åberge; Graham, Sarah E.; Gabrielsen, Maiken Elvestad; Laugsand, Lars Erik; Aukrust, Pål; Vatten, Lars Johan; Damås, Jan Kristian; Ueland, Thor; Janszky, Imre; Zwart, John-Anker; van't Hooft, Ferdinand M.; Seidah, Nabil Georges; Hveem, Kristian; Willer, Cristen; Smith, George Davey; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2019)
      PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce serum LDL (low-density lipoprotein) cholesterol (LDL-C) by increasing uptake in the liver. Although some long-term trials have evaluated their safety, ...