Browsing St. Olavs hospital by Issue Date
Now showing items 21-40 of 2618
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Animal models to study the role of long-term hypergastrinemia in gastric carcinogenesis
(Journal article; Peer reviewed, 2011)Patients with chronic hypergastrinemia due to chronic atrophic gastritis or gastrinomas have an increased risk of developing gastric malignancy, and it has been questioned whether also patients with hypergastrinemia caused ... -
The association between vascular factors and subjective memory impairment in older people : the HUNT study, Norway
(Journal article; Peer reviewed, 2012)Objectives: Subjective memory impairment (SMI) is often considered an early sign of dementia. This study investigates the relationship between SMI and dementia-related vascular factors in older people. Method: This study ... -
Mn-alginate gels as a novel system for controlled release of Mn2+ in manganese-enhanced MRI
(Journal article; Peer reviewed, 2012)The aim of the present study was to test alginate gels of different compositions as a system for controlled release of manganese ions (Mn2+) for application in manganese‐enhanced MRI (MEMRI), in order to circumvent the ... -
The regional research biobank of central Norway - "One biobank, many collections" :
(Journal article; Peer reviewed, 2012)The term biobank is used to designate a systematized collection of biological specimens, often restricted to specimens of human origin (1). Population biobanks, which mainly receive blood samples from large cohorts, have ... -
Gastric Carcinomas Localized to the Cardia
(Journal article; Peer reviewed, 2012)Objectives. Gastric adenocarcinomas localized to the cardia are increasing. Enterochromaffin-like (ECL) cells play a role in gastric carcinogenesis in hypergastrinemia, and the use of proton pump inhibitors (PPI) leading ... -
Sociodemographic differences in medication use, health-care contacts and sickness absence among individuals with medication-overuse headache
(Journal article; Peer reviewed, 2012)The objective of this study was to analyse sociodemographic differences in medication use, health-care contacts and sickness absence among individuals with medication-overuse headache (MOH). A cross-sectional, population ... -
Will (or can) people pay for headache care in a poor country?
(Journal article; Peer reviewed, 2012)We asked whether attempts to introduce headache services in poor countries would be futile on grounds of cost and unsustainability. Using data from a population-based survey in the Republic of Georgia, an exemplary poor ... -
Contextual and time dependent pain in fibromyalgia: An explorative study
(Journal article; Peer reviewed, 2012)Background Little is known about contextual effects on chronic pain, and how vulnerability factors influence pain in different contexts. We wanted to examine if fibromyalgia (FM) pain varied between two social contexts, ... -
Early eczema and the risk of childhood asthma: a prospective, population-based study
(Journal article; Peer reviewed, 2012)Background Severe eczema in young children is associated with an increased risk of developing asthma and rhino-conjunctivitis. In the general population, however, most cases of eczema are mild to moderate. In an unselected ... -
Effectiveness of resistance training in combination with botulinum toxin-A on hand and arm use in children with cerebral palsy: a pre-post intervention study
(Journal article; Peer reviewed, 2012)Background The aim of this pilot study was to examine the effects of additional resistance training after use of Botulinum Toxin-A (BoNT-A) on the upper limbs in children with cerebral palsy (CP). Methods Ten children ... -
Development and delivery of patient treatment in the Trondheim Hip Fracture Trial. A new geriatric in-hospital pathway for elderly patients with hip fracture
(Journal article; Peer reviewed, 2012)Background Hip fractures are common among frail elderly persons and often have serious consequences on function, mobility and mortality. Traditional treatment of these patients is performed in orthopedic departments without ... -
Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients
(Journal article; Peer reviewed, 2012)Background Appetite loss has a major impact on cancer patients. It is exceedingly prevalent, is a prognostic indicator and is associated with inferior quality of life. Cachexia is a multi‐factorial syndrome defined by a ... -
Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy
(Journal article; Peer reviewed, 2012)Background Today's clinical diagnostic tools are insufficient for giving accurate prognosis to breast cancer patients. The aim of our study was to examine the tumor metabolic changes in patients with locally advanced breast ... -
The burden of headache disorders in India: methodology and questionnaire validation for a community-based survey in Karnataka State
(Journal article; Peer reviewed, 2012)Primary headache disorders are a major public-health problem globally and, possibly more so, in low- and middle-income countries. No methodologically sound studies of prevalence and burden of headache in the adult Indian ... -
Comparison of contrast in brightness mode and strain ultrasonography of glial brain tumours
(Journal article; Peer reviewed, 2012)Background Image contrast between normal tissue and brain tumours may sometimes appear to be low in intraoperative ultrasound. Ultrasound imaging of strain is an image modality that has been recently explored for ... -
Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies
(Journal article; Peer reviewed, 2012)Basic cancer research is dependent on reliable in vitro and in vivo tumor models. The serotonin (5‐HT) producing small intestinal neuroendocrine tumor cell line KRJ‐1 has been used in in vitro proliferation and secretion ... -
Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
(Journal article; Peer reviewed, 2012)Introduction Presence of disseminated tumor cells (DTCs) in bone marrow (BM) and circulating tumor cells (CTC) in peripheral blood (PB) predicts reduced survival in early breast cancer. The aim of this study was to determine ... -
Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer
(Peer reviewed; Journal article, 2012)Background: The objective of this study was to assess markers of spermatogenesis in long-term survivors of testicular cancer (TC) according to treatment, and to explore correlations between the markers and associations ... -
Mutasjonstesting ved ikke-småcellet lungekreft
(Peer reviewed; Journal article, 2012)BAKGRUNN. Epidermal vekstfaktor-reseptor (EGFR) tyrosinkinasehemmere (EGFR-TKI) er en relativt ny klasse legemidler til behandling av ikke-småcellet lungekreft. Den nasjonale faggruppen for lungekreft, Norsk Lunge Cancer ... -
Vinorelbine and gemcitabine vs vinorelbine and carboplatin as first-line treatment of advanced NSCLC. A phase III randomised controlled trial by the Norwegian Lung Cancer Study Group
(Journal article; Peer reviewed, 2012)Background: Platinum-based doublet chemotherapy is the standard first-line treatment for advanced non-small cell lung cancer (NSCLC), but earlier studies have suggested that non-platinum combinations are equally effective ...