Blar i St. Olavs hospital på tidsskrift "Neurobiology of Aging"

Viser treff 1-4 av 4

    • Age-adjusted CSF t-tau and NfL do not improve diagnostic accuracy for prodromal Alzheimer’s Disease 

      Knudtzon, Stephanie; Nordengen, Kaja; Grøntvedt, Gøril Rolfseng; Jarholm, Jonas Alexander; Eliassen, Ingvild Vøllo; Selnes, Per; Pålhaugen, Lene; Espenes, Johan Jacob; Gisladottir, Berglind; Waterloo, Knut K; Fladby, Tormod; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Peer reviewed, 2024)
      Cerebrospinal fluid total-tau (t-tau) and neurofilament light chain (NfL) are biomarkers of neurodegeneration and are increased in Alzheimer’s disease (AD). In order to adjust for age-related increases in t-tau and NfL, ...

    • Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults 

      Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner; Rongve, Arvid; Fladby, Tormod; Kirsebom, Bjørn-Eivind Seljelid (Peer reviewed; Journal article, 2023)
      Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a ...

    • CSF neurofilament light may predict progression from amnestic mild cognitive impairment to Alzheimer's disease dementia 

      Lim, Bryant; Grøntvedt, Gøril Rolfseng; Bathala, Pradeepthi; Kale, Shraddha S.; Campbell, Christopher T.; Stengelin, Martin; Sando, Sigrid Botne; Prassas, Ioannis; Diamandis, Eleftherios P.; Bråthen, Geir (Peer reviewed; Journal article, 2021)
      Neurofilament light (NfL) is a promising biomarker of neurodegeneration in Alzheimer's disease (AD). In this study, cerebrospinal fluid (CSF) NfL was measured in a 24-month longitudinal cohort consisting of control (n = ...

    • Longitudinal brain age prediction and cognitive function after stroke 

      Aamodt, Eva Birgitte; Alnæs, Dag; de Lange, Ann-Marie Glasø; Aam, Stina; Schellhorn, Till; Saltvedt, Ingvild Tina; Beyer, Mona Kristiansen; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2022)
      Advanced age is associated with post-stroke cognitive decline. Machine learning based on brain scans can be used to estimate brain age of patients, and the corresponding difference from chronological age, the brain age gap ...