Mass Spectrometric Metabolic Profiling of Human Cells during Cell Cycle and Cytostatic Treatment.

dc.contributor.advisor	Bruheim, Per	nb_NO
dc.contributor.advisor	Nyvold Kvitang, Hans Fredrik	nb_NO
dc.contributor.author	Hole, Nina Lillebø	nb_NO
dc.date.accessioned	2014-12-19T13:22:08Z
dc.date.available	2014-12-19T13:22:08Z
dc.date.created	2013-09-19	nb_NO
dc.date.issued	2013	nb_NO
dc.identifier	649691	nb_NO
dc.identifier	ntnudaim:8912	nb_NO
dc.identifier.uri	http://hdl.handle.net/11250/247918
dc.description.abstract	This project had to different objectives. The first goal was to study the metabolite pool of the cell lines HaCaT and DU145 in the different cell phases in the cell cycle. To obtain this data, the cell lines had to be synchronized. Synchronization was to be achieved either by serum starvation or double thymidine block. The second objective was to study the metabolite pool of HaCaT, DU145 and HEK293 treated with cytostatica. The goal was to detect possible trends for the different cell lines, and this would be the starting point for further testing. The data analysis was performed by using GC-MS QqQ and LC-MS Q-TOF	nb_NO
dc.language	eng	nb_NO
dc.publisher	Institutt for bioteknologi	nb_NO
dc.title	Mass Spectrometric Metabolic Profiling of Human Cells during Cell Cycle and Cytostatic Treatment.	nb_NO
dc.type	Master thesis	nb_NO
dc.source.pagenumber	106	nb_NO
dc.contributor.department	Norges teknisk-naturvitenskapelige universitet, Fakultet for naturvitenskap og teknologi, Institutt for kjemi	nb_NO