Gold(I) Catalyzed Tandem Cyclization Reactions
Master thesis
Permanent lenke
http://hdl.handle.net/11250/247797Utgivelsesdato
2012Metadata
Vis full innførselSamlinger
- Institutt for kjemi [1353]
Sammendrag
Through this study it has been observed that in contrast to propargyl esters which give cyclopropyl products, the high reactivity of propargyl acetals allows a new tandem cyclization to take place, resulting in bicyclic products. It has also been found that steric effects may cause propargyl acetals to react by unexpected pathways. NMR studies confirmed a particularly high reactivity of propargyl acetal compared to propargyl ester. These results show how molecular diversity can easily be achieved by varying the substrates in gold(I) catalysis.