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dc.contributor.authorBjørnevik, Kjetil
dc.contributor.authorRiise, Trond
dc.contributor.authorBenjaminsen, Espen
dc.contributor.authorCelius, Elisabeth Gulowsen
dc.contributor.authorDahl, Ole-Petter
dc.contributor.authorKampman, Margitta Theodora
dc.contributor.authorLøken-Amsrud, Kristin Ingeleiv
dc.contributor.authorMidgard, Rune
dc.contributor.authorMyhr, Kjell-Morten
dc.contributor.authorTorkildsen, Øivind
dc.contributor.authorVatne, Anita
dc.contributor.authorGrytten, Nina
dc.identifier.citationMultiple Sclerosis. 2016, 23 213-219.nb_NO
dc.description.abstractBackground: The conflicting results from studies on socioeconomic status (SES) and multiple sclerosis (MS) risk might be due to a change in the distribution of environmental exposures over time or to methodological limitations in previous research. Objective: To examine the association between SES and MS risk during 50 years. Methods: We included patients registered in Norwegian MS registries and prevalence studies born between 1930 and 1979, and identified their siblings and parents using the Norwegian Population Registry. Information on education was retrieved from the National Education Registry, categorized into four levels (primary, secondary, undergraduate and graduate) and compared in patients and siblings using conditional logistic regression. Results: A total of 4494 MS patients and 9193 of their siblings were included in the analyses. Level of education was inversely associated with MS risk (p trend < 0.001) with an odds ratio (OR) of 0.73 (95% confidence interval (CI): 0.59–0.90) when comparing the highest and lowest levels. The effect estimates did not vary markedly between participants born before or after the median year of birth (1958), but we observed a significant effect modification by parental education (p = 0.047). Conclusion: Level of education was inversely associated with MS risk, and the estimates were similar in the earliest and latest birth cohorts.nb_NO
dc.publisherSAGE Publicationsnb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleLevel of education and multiple sclerosis risk over a 50-year period: Registry-based sibling studynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalMultiple Sclerosisnb_NO
dc.description.localcode© The Author(s), 2016.nb_NO
cristin.unitnameDMF fakultetsadministrasjon

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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal