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dc.contributor.authorSargénius, Hanna
dc.contributor.authorLydersen, Stian
dc.contributor.authorHestad, Knut
dc.identifier.citationBMC Obesity. 2017, 4 (6), .nb_NO
dc.description.abstractBackground:Previous research has shown cognitive dysfunction to be present in a significant number ofindividuals with obesity. The objective of this study was to assess the neuropsychological profile of morbidlyobese patients referred to weight-loss treatment.Methods:An extensive battery of neuropsychological tests with well-known normative data covering variouscognitive domains was administered to 96 patients. The test results were transformed to z-scores for comparisonswith normative data. As a means of determining level of cognitive impairmentwithinthe group, deficit scores wereapplied. Group comparisons on the different cognitive domains were conducted between patients with depressivesymptoms and patients reporting no such symptoms.Results:As illustrated in mean z-scores, the patients demonstrated lower performance compared to normative dataon visual memory (mean -.26, CI -.43 to -.09,p= .003), speed of information processing (mean -.22, CI -.34 to -.09,p= .001), executive functions (mean -.28, CI -.40 to -.16,p< .001), and attention/vigilance (mean -.25, CI -.37 to -.13,p< .001). Their performance was good on verbal fluency (mean .24, CI .04 to .44,p= .016) and verbal memory(mean .55, CI .38 to .72,p< .001). No significant performance differences were observed in the cognitive domainsof visuospatial ability, motor function, and working memory. The deficit scores, however, revealed working memoryand motor function to be significantly impaired within the group as well. Patients with depressive symptoms differed from patients without such symptoms on visual memory (mean .43, CI .07 to .80,p= .021).Conclusions:Some characteristic cognitive weaknesses and strengths were evident at the group level, althoughpronounced variation was observed. Deficits in executive functions, information processing, and attention shouldbe taken into consideration in clinical practice.nb_NO
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleNeuropsychological function in individuals with morbid obesity: A cross-sectional studynb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalBMC Obesitynb_NO
dc.description.localcode© The Author(s). 2017Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0International License (, which permits unrestricted use, distribution, andreproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link tothe Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver( applies to the data made available in this article, unless otherwise stated.nb_NO
cristin.unitnamePsykologisk institutt
cristin.unitnameRegionalt kunnskapssenter for barn og unge - Psykisk helse og barnevern

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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal