Blar i Institutt for bioingeniørfag på forfatter "To, Vu"
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A high-throughput drug combination screen of targeted small molecule inhibitors in cancer cell lines
Flobak, Åsmund; Niederdorfer, Barbara; To, Vu; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid (Journal article; Peer reviewed, 2019)While there is a high interest in drug combinations in cancer therapy, openly accessible datasets for drug combination responses are sparse. Here we present a dataset comprising 171 pairwise combinations of 19 individual ... -
High-throughput screening reveals higher synergistic effect of MEK inhibitor combinations in colon cancer spheroids
Folkesson, Evelina; Niederdorfer, Barbara; To, Vu; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid; Flobak, Åsmund (Peer reviewed; Journal article, 2020)Drug combinations have been proposed to combat drug resistance, but putative treatments are challenged by low bench-to-bed translational efficiency. To explore the effect of cell culture format and readout methods on ...