Blar i Institutt for psykisk helse på forfatter "Agartz, Ingrid"
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Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending
Bell, Christina; Tesli, Natalia; Gurholt, Tiril Pedersen; Rokicki, Jaroslav; Hjell, Gabriela; Fischer-Vieler, Thomas; Melle, Ingrid; Agartz, Ingrid; Andreassen, Ole; Rasmussen, Kirsten; Johansen, Ragnhild; Friestad, Christine; Haukvik, Unn Kristin Hansen (Peer reviewed; Journal article, 2021)The amygdala is involved in fear perception and aggression regulation, and smaller volumes have been associated with psychotic and non-psychotic violence. We explored the relationship between amygdala nuclei volumes in ... -
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Andlauer, Till F.M.; Guzman-Parra, José; Streit, Fabian; Strohmaier, Jana; González, Maria José; Flores, Susana Gil; Fabeiro, Francisco J. Cabaleiro; Noriega, Francisco del Río; Perez, Fermin Perez; González, Jesus Haro; Diaz, Guillermo Orozco; Diego-Otero, Yolanda de; Moreno-Küstner, Berta; Auburger, Georg; Degenhardt, Franziska; Heilmann-Heimbach, Stefanie; Herms, Stefan; Hoffmann, Per; Frank, Josef; Foo, Jerome C.; Treutlein, Jens; Witt, Stephanie H.; Cichon, Sven; Kogevinas, Manolis; Bøen, Erlend; Dale, Anders M.; Djurovic, Srdjan; Elvsåshagen, Torbjørn; Reinbold, Céline Sonja; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Melle, Ingrid; Ødegaard, Ketil Joachim; Stordal, Eystein; Andreassen, Ole; Rivas, Fabio; Mayoral, Fermín; Müller-Myhsok, Bertram; Forstner, Andreas J.; Nöthen, Markus M.; Rietschel, Marcella; Stahl, Eli A.; Breen, Gerome; McQuillin, Andrew; Ripke, Stephan; Trubetskoy, Vassily; Mattheisen, Manuel; Wang, Yunpeng; Morken, Gunnar; Vaaler, Arne (Peer reviewed; Journal article, 2021)Multiplex families with a high prevalence of a psychiatric disorder are often examined to identify rare genetic variants with large effect sizes. In the present study, we analysed whether the risk for bipolar disorder (BD) ... -
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Jensen, Søren Beck; Sheikh, Mashhood Ahmed; Akkouh, Ibrahim Ahmed; Szabo, Attila; O'Connell, Kevin Sean; Lekva, Tove; Engh, John; Agartz, Ingrid; Elvsåshagen, Torbjørn; Ormerod, Monica Bettina E. Greenwood; Weibell, Melissa Anne Elin Authen; Johnsen, Erik; Kroken, Rune Andreas; Melle, Ingrid; Drange, Ole Kristian; Nærland, Terje; Vaaler, Arne; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)Abstract Background and Hypothesis Gut microbiota alterations have been reported in severe mental illness (SMI) but fewer studies have probed for signs of gut barrier disruption and inflammation. We hypothesized that ... -
Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl, Eli A.; Breen, Gerome; Forstner, Andreas J.; McQuillin, Andrew; Ripke, Stephan; Trubetskoy, Vassily; Mattheisen, Manuel; Wang, Yunpeng; Coleman, Jonathan R.I.; Gaspar, Héléna A.; de Leeuw, Christiaan A.; Steinberg, Stacy; Pavlides, Jennifer M. Whitehead; Trzaskowski, Maciej; Byrne, Enda M.; Pers, Tune H.; Holmans, Peter A.; Richards, Alexander L.; Abbott, Liam; Agerbo, Esben; Akil, Huda; Albani, Diego; Alliey-Rodriguez, Ney; Als, Thomas D.; Anjorin, Adebayo; Antilla, Verneri; Awasthi, Swapnil; Badner, Judith A.; Bækvad-Hansen, Marie; Barchas, Jack D.; Bass, Nicholas; Bauer, Michael; Belliveau, Richard; Bergen, Sarah E.; Pedersen, Carsten Bøcker; Bøen, Erlend; Boks, Marco P.; Boocock, James; Budde, Monika; Bunney, William; Burmeister, Margit; Bybjerg-Grauholm, Jonas; Byerley, William; Casas, Miquel; Cerrato, Felecia; Cervantes, Pablo; Chambert, Kimberly; Charney, Alxander W.; Chen, Danfeng; Churchhouse, Claire; Clarke, Toni-Kim; Coryell, William; Craig, David W.; Cruceanu, Cristiana; Curtis, David; Czerski, Piotr M.; Dale, Anders; de Jong, Simone; Degenhardt, Franziska; Del-Favero, Jurgen; Depaulo, J. Raymond; Djurovic, Srdjan; Dobbyn, Amanda L.; Dumont, Ashley; Elvsåshagen, Torbjørn; Escott-Price, Valentina; Fan, Chun Chieh; Fischer, Sascha B.; Flickinger, Matthew; Foroud, Tatiana M.; Forty, Liz; Frank, Josef; Fraser, Christine; Freimer, Nelson B.; Frisén, Louise; Gade, Katrin; Gage, Diane; Garnham, Julie; Giambartolomei, Claudia; Pedersen, Marianne Giørtz; Goldstein, Jaqueline; Gordon, Scott D.; Gordon-Smith, Katherine; Green, Elaine K.; Green, Melissa J.; Greenwood, Tifany A.; Grove, Jakob; Guan, Weihua; Guzman-Parra, José; Hamshere, Marian L.; Hautzinger, Martin; Heilbronner, Urs; Herms, Stefan; Hipolito, Maria; Hoffmann, Per; Holland, Dominic; Huckins, Laura; Jamain, Stéphane; Johnson, Jessica S.; Juréus, Anders; Kandaswamy, Radhika; Karlsson, Robert; Kennedy, James L.; Kittel-Schneider, Sarah; Knowles, James A.; Kogevinas, Manolis; Koller, Anna C.; Kupka, Ralph; Lavebratt, Catharina; Lawrence, Jacob; Lawson, William B.; Leber, Markus; Lee, Phil H.; Levy, Shawn E.; Li, Jun Z.; Liu, Chunyu; Lucae, Susanne; Maaser, Anna; MacIntyre, Donald J.; Mahon, Pamela B.; Maier, Wolfgang; Martinsson, Lina; McCarroll, Steve; McGuffin, Peter; McInnis, Melvin G.; McKay, James D.; Medeiros, Helena; Medland, Sarah E.; Meng, Fan; Milani, Lili; Montgomery, Grant W.; Morris, Derek W.; Mühleisen, Thomas W.; Mullins, Niamh; Nguyen, Hoang; Nievergelt, Caroline M.; Adolfsson, Annelie Nordin; Nwulia, Evaristus A.; O'Donovan, Claire; Loohuis, Loes M. Olde; Ori, Anil P.S.; Oruc, Lilijana; Ösby, Urban; Perlis, Roy H.; Perry, Amy; Pfennig, Andrea; Potash, James B.; Purcell, Shaun M.; Regeer, Eline J.; Reif, Andreas; Reinbold, Céline S.; Rice, John P.; Rivas, Fabio; Rivera, Margarita; Roussos, Panos; Ruderfer, Douglas M.; Ryu, Euijung; Sánchez-Mora, Cristina; Schatzberg, Alan F.; Scheftner, William A.; Schork, Nicholas J.; Shannon Weickert, Cynthia; Shehktman, Tatyana; Shilling, Paul D.; Sigurdsson, Engilbert; Slaney, Claire; Smeland, Olav Bjerkehagen; Sobell, Janet L.; Søholm Hansen, Christine; Spijker, Anne T.; St Clair, David; Steffens, Michael; Strauss, John S.; Streit, Fabian; Strohmaier, Jana; Szelinger, Szabolcs; Thompson, Robert C.; Thorgeirsson, Thorgeir E; Treutlein, Jens; Vedder, Helmut; Wang, Weiqing; Watson, Stanley J.; Weickert, Thomas W.; Witt, Stephanie H.; Xi, Simon; Xu, Wei; Young, Allan H.; Zandi, Peter; Zhang, Peng; Zöllner, Sebastian; Adolfsson, Rolf; Agartz, Ingrid; Alda, Martin; Backlund, Lena; Baune, Bernhard T.; Bellivier, Frank; Berrettini, Wade H.; Biernacka, Joanna M.; Blackwood, Douglas H.R.; Boehnke, Michael; Børglum, Anders D.; Corvin, Aiden; Craddock, Nicholas; Daly, Mark J.; Dannlowski, Udo; Esko, Tõnu; Etain, Bruno; Frye, Mark; Fullerton, Janice M.; Gershon, Elliot S.; Gill, Michael; Goes, Fernando; Grigoroiu-Serbanescu, Maria; Hauser, Joanna; Hougaard, David M.; Hultman, Christina M.; Jones, Ian; Jones, Lisa A.; Kahn, René S.; Kirov, George; Landén, Mikael; Leboyer, Marion; Lewis, Cathryn M.; Li, Qingqin S.; Lissowska, Jolanta; Martin, Nicholas G.; Mayoral, Fermin; McElroy, Susan L.; McIntosh, Andrew M.; McMahon, Francis J.; Melle, Ingrid; Metspalu, Andres; Mitchell, Philip B.; Morken, Gunnar; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Myers, Richard M.; Neale, Benjamin M.; Nimgaonkar, Vishwajit; Nordentoft, Merete; Nöthen, Markus M.; O'Donovan, Michael C; Ødegaard, Ketil Joachim; Owen, Michael J.; Paciga, Sara A.; Pato, Carlos; Pato, Michele T.; Posthuma, Danielle; Ramos-Quiroga, Josep Antoni; Ribasés, Marta; Rietschel, Marcella; Rouleau, Guy A.; Schalling, Martin; Schofield, Peter R.; Schulze, Thomas G.; Serretti, Alessandro; Smoller, Jordan W.; Stefansson, Hreinn; Stefansson, Kari; Stordal, Eystein; Sullivan, Patrick F.; Turecki, Gustavo; Vaaler, Arne; Vieta, Eduard; Vincent, John B.; Werge, Thomas; Nurnberger, John I.; Wray, Naomi R.; Di Florio, Arianna; Edenberg, Howard J.; Cichon, Sven; Ophoff, Roel A.; Scott, Laura J.; Andreassen, Ole Andreas; Kelsoe, John; Sklar, Pamela (Journal article; Peer reviewed, 2019)Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with ... -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
Lee, Phil H.; Antilla, Verneri; Won, Hyejung; Bettella, Francesco; Agartz, Ingrid; Dale, Anders; Nærland, Terje; Elvsåshagen, Torbjørn; Ødegaard, Ketil Joachim; Melle, Ingrid; Knudsen, Gun Peggy Strømstad; Le Hellard, Stephanie; Reichborn-Kjennerud, Ted; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas; Neale, Benjamin M; Kendler, Kenneth S.; Smoller, Jordan W. (Peer reviewed; Journal article, 2019)Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed ... -
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Docherty, Anna R.; Mullins, Niamh; Ashley-Koch, Allison E.; Qin, Xuejun; Coleman, Jonathan R.I.; Shabalin, Andrey; Kang, JooEun; Murnyak, Balasz; Wendt, Frank; Adams, Mark; Campos, Adrian I.; DiBlasi, Emily; Fullerton, Janice M.; Kranzler, Henry R.; Bakian, Amanda V.; Monson, Eric T.; Rentería, Miguel E.; Walss-Bass, Consuelo; Andreassen, Ole; Behera, Chittaranjan; Bulik, Cynthia M.; Edenberg, Howard J.; Adolfsson, Rolf; Agartz, Ingrid; Alda, Martin; Alfredsson, Lars; Appadurai, Vivek; Artigas, María Soler; Djurovic, Srdjan; Foo, Jerome C.; Forstner, Andreas J.; Frye, Mark; Gatt, Justine; Melle, Ingrid; Mitchell, Philip B.; Molina, Esther; Morken, Gunnar; Smeland, Olav Bjerkehagen; Smoller, Jordan W.; Sonuga-Barke, Edmund J.S.; Trzaskowski, Maciej; Tsuang, Ming T.; Turecki, Gustavo; Vilar-Ribó, Laura; Vincent, John B.; Völzke, Henry; Walters, James T.R.; Weickert, Cynthia Shannon; Weickert, Thomas W.; Weissman, Myrna M. (Peer reviewed; Journal article, 2023)Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale genome-wide association studies (GWASs) recently discovered and cross-validated genome-wide significant (GWS) loci for ... -
GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores
Mullins, Niamh; Bigdeli, Tim B.; Børglum, Anders D.; Coleman, Jonathan R.I.; Demontis, Ditte; Mehta, Divya; Power, Robert A.; Ripke, Stephan; Stahl, Eli A.; Starnawska, Anna; Anjorin, Adebayo; Corvin, Aiden; Sanders, Alan R.; Forstner, Andreas J.; Reif, Andreas; Koller, Anna C.; Świątkowska, Beata; Baune, Bernhard T.; Müller-Myhsok, Bertram; Penninx, Brenda W.J.H.; Pato, Carlos; Zai, Clement; Rujescu, Dan; Hougaard, David M.; Quested, Digby; Levinson, Douglas F.; Binder, Elisabeth B.; Byrne, Enda M.; Agerbo, Esben; Streit, Fabian; Mayoral, Fermin; Bellivier, Frank; Degenhardt, Franziska; Breen, Gerome; Morken, Gunnar; Turecki, Gustavo; Rouleau, Guy A.; Grabe, Hans J.; Völzke, Henry; Jones, Ian; Giegling, Ina; Agartz, Ingrid; Melle, Ingrid; Lawrence, Jacob; Walters, James T.R.; Strohmaier, Jana; Shi, Jianxin; Hauser, Joanna; Biernacka, Joanna M.; Vincent, John B.; Kelsoe, John; Strauss, John S.; Lissowska, Jolanta; Pimm, Jonathan; Smoller, Jordan W.; Guzman-Parra, José; Berger, Klaus; Scott, Laura J.; Jones, Lisa A.; Azevedo, M. Helena; Trzaskowski, Maciej; Kogevinas, Manolis; Rietschel, Marcella; Boks, Marco; Ising, Marcus; Grigoroiu-Serbanescu, Maria; Hamshere, Marian L.; Leboyer, Marion; Frye, Mark; Nöthen, Markus M.; Alda, Martin; Preisig, Martin; Nordentoft, Merete; Boehnke, Michael; O'Donovan, Michael C.; Owen, Michael J.; Pato, Michele T.; Renteriá, Miguel E.; Budde, Monika; Weissman, Myrna M.; Wray, Naomi R.; Bass, Nicholas; Craddock, Nicholas; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas; Mors, Ole; Gejman, Pablo V.; Sklar, Pamela; McGrath, Patrick; Hoffmann, Per; McGuffin, Peter; Lee, Phil H.; Mortensen, Preben Bo; Kahn, René S.; Ophoff, Roel A.; Adolfsson, Rolf; Van der Auwera, Sandra; Djurovic, Srdjan; Kloiber, Stefan; Heilmann-Heimbach, Stefanie; Jamain, Stéphane; Hamilton, Steven P.; McElroy, Susan L.; Lucae, Susanne; Cichon, Sven; Schulze, Thomas G.; Hansen, Thomas; Werge, Thomas; Air, Tracy M.; Nimgaonkar, Vishwajit; Appadurai, Vivek; Cahn, Wiepke; Milaneschi, Yuri; Fanous, Ayman H.; Kendler, Kenneth S.; McQuillin, Andrew; Lewis, Cathryn M. (Journal article; Peer reviewed, 2019)Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of suicide attempt is partially distinct from that of the psychiatric ... -
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia A comparison among participants between 2 and 53 years
Hope, Sigrun; Nærland, Terje; Høyland, Anne Lise; Torske, Tonje; Malt, Eva; Abrahamsen, Tore G; Nerhus, Mari; Wedervang-Resell, Kirsten; Lonning, Vera Louise Hiorth; Johannessen, Jarle; Steen, Nils Eiel; Agartz, Ingrid; Stenberg, Nina; Hundhausen, Thomas Eckhard; Mørkrid, Lars; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2020)Recent studies suggest that both high and low levels of vitamin B12 (vitB12) may have negative health impacts. We measured VitB12 in patients with the Neurodevelopmental disorders (ND) (n = 222), comprised of Autism Spectrum ... -
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Szabo, Attila; O’Connell, Kevin; Ueland, Thor; Ahmed, Mashhood Sheikh; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John Abel; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Auten Weibell, Melissa; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2022)Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ... -
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2021)Background -Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ... -
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
Mørch, Ragni Helene; Dieset, Ingrid; Færden, Ann; Reponen, Elina Johanna; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Gardsjord, Erlend Strand; Aas, Monica; Iversen, Trude; Joa, Inge; Morken, Gunnar; Agartz, Ingrid; Melle, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Ueland, Thor; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2019)Background. Inflammation and immune activation have been implicated in the pathogenesis of severe mental disorders and cardiovascular disease (CVD). Despite high level of comorbidity, many studies of the immune system in ... -
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Andreou, Dimitrios; Steen, Nils Eiel; Jørgensen, Kjetil Nordbø; Smelror, Runar Elle; Wedervang-Resell, Kirsten; Nerland, Stener; Westlye, Lars Tjelta; Nærland, Terje; Myhre, Anne Margrethe; Joa, Inge; Reitan, Solveig Merete Klæbo; Vaaler, Arne; Morken, Gunnar; Bøen, Erlend; Elvsåshagen, Torbjørn; Boye, Birgitte; Malt, Ulrik Fredrik; Aukrust, Pål; Skrede, Silje; Kroken, Rune Andreas; Johnsen, Erik; Djurovic, Srdjan; Andreassen, Ole; Ueland, Thor; Agartz, Ingrid (Peer reviewed; Journal article, 2021)Background Both neurodegenerative and neurodevelopmental abnormalities have been suggested to be part of the etiopathology of severe mental illness (SMI). Neuron-specific enolase (NSE), mainly located in the neuronal ... -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, Vassily; Pardiñas, Antonio F.; Qi, Ting; Panagiotaropoulou, Georgia; Awasthi, Swapnil; Bigdeli, Tim B.; Bryois, Julien; Chen, Chia-Yen; Dennison, Charlotte A.; Hall, Lynsey S.; Lam, Max; Watanabe, Kyoko; Frei, Oleksandr; Ge, Tian; Harwood, Janet C.; Koopmans, Frank; Magnusson, Sigurdur; Richards, Alexander L.; Sidorenko, Julia; Wu, Yang; Zeng, Jian; Grove, Jakob; Kim, Minsoo; Li, Zhiqiang; Voloudakis, Georgios; Zhang, Wen; Adams, Mark; Agartz, Ingrid; Atkinson, Elizabeth G.; Agerbo, Esben; Al Eissa, Mariam; Albus, Margot; Alexander, Madeline; Alizadeh, Behrooz Z.; Alptekin, Köksal; Als, Thomas D.; Amin, Farooq; Arolt, Volker; Arrojo, Manuel; Athanasiu, Lavinia; Azevedo, Maria Helena; Bacanu, Silviu A.; Bass, Nicholas J.; Begemann, Martin; Belliveau, Richard A.; Bene, Judit; Benyamin, Beben; Bergen, Sarah E.; Blasi, Giuseppe; Bobes, Julio; Bonassi, Stefano; Braun, Alice; Bressan, Rodrigo Affonseca; Bromet, Evelyn J.; Bruggeman, Richard; Buckley, Peter F.; Buckner, Randy L.; Bybjerg-Grauholm, Jonas; Cahn, Wiepke; Cairns, Murray J.; Calkins, Monica E.; Carr, Vaughan J.; Castle, David; Catts, Stanley V.; Chambert, Kimberley D.; Chan, Raymond C K; Chaumette, Boris; Cheng, Wei; Cheung, Eric F C; Chong, Siow Ann; Cohen, David; Consoli, Angèle; Cordeiro, Quirino; Costas, Javier; Curtis, Charles; Davidson, Michael; Davis, Kenneth L.; de Haan, Lieuwe; Degenhardt, Franziska; DeLisi, Lynn E.; Demontis, Ditte; Dickerson, Faith; Dikeos, Dimitris; Dinan, Timothy; Djurovic, Srdjan; Duan, Jubao; Ducci, Giuseppe; Dudbridge, Frank; Eriksson, Johan G.; Fañanás, Lourdes; Faraone, Stephen; Fiorentino, Alessia; Forstner, Andreas; Frank, Josef; Freimer, Nelson B.; Fromer, Menachem; Frustaci, Alessandra; Gadelha, Ary; Genovese, Giulio; Gershon, Elliot S.; Giannitelli, Marianna; Giegling, Ina; Giusti-Rodríguez, Paola; Godard, Stephanie; Goldstein, Jacqueline I.; González Peñas, Javier; González-Pinto, Ana; Gopal, Srihari; Gratten, Jacob; Green, Michael F.; Greenwood, Tiffany A.; Guillin, Olivier; Gülöksüz, Sinan; Gur, Raquel E.; Gur, Ruben C.; Gutiérrez, Blanca; Hahn, Eric; Hakonarson, Hakon; Haroutunian, Vahram; Hartmann, Annette M.; Harvey, Carol; Hayward, Caroline; Henskens, Frans A.; Herms, Stefan; Hoffmann, Per; Howrigan, Daniel P.; Ikeda, Masashi; Iyegbe, Conrad; Joa, Inge; Julià, Antonio; Kähler, Anna Katarina; Kam-Thong, Tony; Kamatani, Yoichiro; Karachanak-Yankova, Sena; Kebir, Oussama; Keller, Matthew C.; Kelly, Brian J.; Khrunin, Andrey; Kim, Sung-Wan; Klovins, Janis; Kondratiev, Nikolay; Konte, Bettina; Kraft, Julia; Kubo, Michiaki; Kučinskas, Vaidutis; Kučinskiene, Zita Ausrele; Kusumawardhani, Agung; Kuzelova-Ptackova, Hana; Landi, Stefano; Lazzeroni, Laura C.; Lee, Phil H.; Legge, Sophie E.; Lehrer, Douglas S.; Lencer, Rebecca; Lerer, Bernard; Li, Miaoxin; Lieberman, Jeffrey; Light, Gregory A.; Limborska, Svetlana; Liu, Chih-Min; Lönnqvist, Jouko; Loughland, Carmel M.; Lubinski, Jan; Luykx, Jurjen J.; Lynham, Amy; Macek, Milan; Mackinnon, Andrew; Magnusson, Patrik K E; Maher, Brion S.; Maier, Wolfgang; Malaspina, Dolores; Mallet, Jacques; Marder, Stephen R.; Marsal, Sara; Martin, Alicia R.; Martorell, Lourdes; Mattheisen, Manuel; McCarley, Robert W.; McDonald, Colm; McGrath, John J.; Medeiros, Helena; Meier, Sandra; Melegh, Bela; Melle, Ingrid; Mesholam-Gately, Raquelle I.; Metspalu, Andres; Michie, Patricia T.; Milani, Lili; Milanova, Vihra; Mitjans, Marina; Molden, Espen; Molina, Esther; Molto, María Dolores; Mondelli, Valeria; Moreno, Carmen; Morley, Christopher P.; Muntané, Gerard; Murphy, Kieran C.; Myin-Germeys, Inez; Nenadić, Igor; Nestadt, Gerald; Nikitina-Zake, Liene; Noto, Cristiano; Nuechterlein, Keith H.; O'Brien, Niamh Louise; O'Neill, F Anthony; Oh, Sang-Yun; Olincy, Ann; Ota, Vanessa Kiyomi; Pantelis, Christos; Papadimitriou, George N.; Parellada, Mara; Paunio, Tiina; Pellegrino, Renata; Periyasamy, Sathish; Perkins, Diana O.; Pfuhlmann, Bruno; Pietiläinen, Olli; Pimm, Jonathan; Porteous, David; Powell, John; Quattrone, Diego; Quested, Digby; Radant, Allen D.; Rampino, Antonio; Rapaport, Mark H.; Rautanen, Anna; Reichenberg, Abraham; Roe, Cheryl; Roffman, Joshua L.; Roth, Julian; Rothermundt, Matthias; Rutten, Bart P F; Saker-Delye, Safaa; Salomaa, Veikko; Sanjuan, Julio; Santoro, Marcos Leite; Savitz, Adam; Schall, Ulrich; Scott, Rodney J.; Seidman, Larry J.; Sharp, Sally Isabel; Shi, Jianxin; Siever, Larry J.; Sigurdsson, Engilbert; Sim, Kang; Skarabis, Nora; Slominsky, Petr; So, Hon-Cheong; Sobell, Janet L.; Söderman, Erik; Stain, Helen J.; Steen, Nils Eiel; Steixner-Kumar, Agnes A.; Stögmann, Elisabeth; Stone, William S.; Straub, Richard E.; Streit, Fabian; Strengman, Eric; Stroup, T. Scott; Subramaniam, Mythily; Sugar, Catherine A.; Suvisaari, Jaana; Svrakic, Dragan M.; Swerdlow, Neal R.; Szatkiewicz, Jin P.; Ta, Thi Minh Tam; Takahashi, Atsushi; Terao, Chikashi; Thibaut, Florence; Toncheva, Draga; Tooney, Paul A.; Torretta, Silvia; Tosato, Sarah; Tura, Gian Battista; Turetsky, Bruce I.; Üçok, Alp; Vaaler, Arne; van Amelsvoort, Therese; van Winkel, Ruud; Veijola, Juha; Waddington, John; Walter, Henrik; Waterreus, Anna; Webb, Bradley T.; Weiser, Mark; Williams, Nigel M.; Witt, Stephanie H.; Wormley, Brandon K.; Wu, Jing Qin; Xu, Zhida; Yolken, Robert; Zai, Clement C.; Zhou, Wei; Zhu, Feng; Zimprich, Fritz; Atbaşoğlu, Eşref Cem; Ayub, Muhammad; Benner, Christian; Bertolino, Alessandro; Black, Donald W.; Bray, Nicholas J.; Breen, Gerome; Buccola, Nancy G.; Byerley, William F.; Chen, Wei J.; Cloninger, C Robert; Crespo-Facorro, Benedicto; Donohoe, Gary; Freedman, Robert; Galletly, Cherrie; Gandal, Michael J.; Gennarelli, Massimo; Hougaard, David M.; Hwu, Hai-Gwo; Jablensky, Assen V.; McCarroll, Steven A.; Moran, Jennifer L.; Mors, Ole; Mortensen, Preben B.; Müller-Myhsok, Bertram; Neil, Amanda L.; Nordentoft, Merete; Pato, Michele T.; Petryshen, Tracey L.; Pirinen, Matti; Pulver, Ann E.; Schulze, Thomas G.; Silverman, Jeremy M.; Smoller, Jordan W.; Stahl, Eli A.; Tsuang, Debby W.; Vilella, Elisabet; Wang, Shi-Heng; Xu, Shuhua; Adolfsson, Rolf; Arango, Celso; Baune, Bernhard T.; Belangero, Sintia Iole; Børglum, Anders D.; Braff, David; Bramon, Elvira; Buxbaum, Joseph D.; Campion, Dominique; Cervilla, Jorge A.; Cichon, Sven; Collier, David A.; Corvin, Aiden; Curtis, David; Forti, Marta Di; Domenici, Enrico; Ehrenreich, Hannelore; Escott-Price, Valentina; Esko, Tõnu; Fanous, Ayman H.; Gareeva, Anna; Gawlik, Micha; Gejman, Pablo V.; Gill, Michael; Glatt, Stephen J.; Golimbet, Vera; Hong, Kyung Sue; Hultman, Christina M.; Hyman, Steven E.; Iwata, Nakao; Jönsson, Erik Gunnar; Kahn, René S; Kennedy, James L.; Khusnutdinova, Elza; Kirov, George; Knowles, James A.; Krebs, Marie-Odile; Laurent-Levinson, Claudine; Lee, Jimmy; Lencz, Todd; Levinson, Douglas F.; Li, Qingqin S.; Liu, Jianjun; Malhotra, Anil K.; Malhotra, Dheeraj; McIntosh, Andrew; McQuillin, Andrew; Menezes, Paulo R.; Morgan, Vera A.; Morris, Derek W.; Mowry, Bryan J.; Murray, Robin M.; Nimgaonkar, Vishwajit; Nöthen, Markus M.; Ophoff, Roel A.; Paciga, Sara A.; Palotie, Aarno; Pato, Carlos N.; Qin, Shengying; Rietschel, Marcella; Riley, Brien P.; Rivera, Margarita; Rujescu, Dan; Saka, Meram C.; Sanders, Alan R.; Schwab, Sibylle G.; Serretti, Alessandro; Sham, Pak C.; Shi, Yongyong; St Clair, David; Stefánsson, Hreinn; Stefansson, Kari; Tsuang, Ming T.; van Os, Jim; Vawter, Marquis P.; Weinberger, Daniel R.; Werge, Thomas; Wildenauer, Dieter B.; Yu, Xin; Yue, Weihua; Holmans, Peter A.; Pocklington, Andrew J.; Roussos, Panos; Vassos, Evangelos; Verhage, Matthijs; Visscher, Peter M.; Yang, Jian; Posthuma, Danielle; Andreassen, Ole; Kendler, Kenneth S.; Owen, Michael J.; Wray, Naomi R.; Daly, Mark J.; Huang, Hailiang; Neale, Benjamin M.; Sullivan, Patrick F.; Ripke, Stephan; Walters, James T R; O'Donovan, Michael C. (Peer reviewed; Journal article, 2022)Schizophrenia has a heritability of 60–80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control ... -
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Engh, John; Ueland, Thor; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Wedervang-Resell, Kirsten; Weibell, Melissa; Westlye, Lars Tjelta; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole (Peer reviewed; Journal article, 2021)Background Immune dysfunction has been implicated in the pathogenesis of schizophrenia and other nonaffective psychosis (SCZ), bipolar spectrum disorder (BIP) and major depressive disorder (MDD). The cytokines B cell-activating ... -
Psychopathy subdomains in violent offenders with and without a psychotic disorder
Bell, Christina; Tesli, Natalia; Gurholt, Tiril Pedersen; Rokicki, Jaroslav; Hjell, Gabriela; Fischer-Vieler, Thomas; Melle, Ingrid; Agartz, Ingrid; Andreassen, Ole; Ringen, Petter Andreas; Rasmussen, Kirsten; Dahl, Hilde; Friestad, Christine; Haukvik, Unn Kristin Hansen (Peer reviewed; Journal article, 2022)Background Violence in psychosis has been linked to antisocial behavior and psychopathy traits. Psychopathy comprises aspects of interpersonal, affective, lifestyle, and antisocial traits which may be differently involved ... -
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)Background Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ... -
White Matter Matters: Unraveling Violence in Psychosis and Psychopathy
Tesli, Natalia; Rokicki, Jaroslav; Maximov, Ivan; Bell, Christina; Hjell, Gabriela; Gurholt, Tiril Pedersen; Fischer-Vieler, Thomas; Bang, Nina; Tesli, Martin Steen; Westlye, Lars Tjelta; Andreassen, Ole; Melle, Ingrid; Agartz, Ingrid; Rasmussen, Kirsten; Johansen, Ragnhild; Friestad, Christine; Haukvik, Unn Kristin Hansen (Peer reviewed; Journal article, 2021)Individuals with psychotic disorders have an increased risk of committing acts of violence. Neurobiological support for the extent to which violence in psychosis is driven by psychotic symptoms and/or antisocial traits ...