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dc.contributor.authorHestad, Knut
dc.contributor.authorWeider, Siri
dc.contributor.authorNilsen, Kristian Bernhard
dc.contributor.authorIndredavik, Marit Sæbø
dc.contributor.authorSand, Trond
dc.identifier.citationNeuropsychiatric Disease and Treatment 2016, 12:2419-2423nb_NO
dc.description.abstractObjective: To conduct a blind study of quantitative electroencephalogram-band amplitudes in patients with anorexia nervosa (AN) and healthy controls. Methods: Twenty-one patients with AN and 24 controls were examined with eyes-closed 16-channel electroencephalogram. Main variables were absolute alpha, theta, and delta amplitudes in frontal, temporal, and posterior regions. Results: There were no significant differences between the AN patients and controls regarding absolute regional band amplitudes in µV. Borderline significance was found for anterior theta (P=0.051). Significantly increased left and right frontal electrode theta amplitude was found in AN patients (F3, P=0.014; F4, P=0.038) compared to controls. Significant differences were also observed for secondary variables: lower values for relative parietooccipital delta and frontocentral alpha activity among AN patients than among controls. Conclusion: We observed slight excess frontal theta and lower relative alpha and delta amplitudes among AN patients than among controls. This pattern is possibly related to a slight frontal lobe dysfunction in AN, or it may reflect increased attention/vigilance or another state-related change in patients with AN compared to healthy controls.nb_NO
dc.publisherDove Medical Pressnb_NO
dc.titleIncreased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controlsnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.source.journalNeuropsychiatric Disease and Treatmentnb_NO
dc.description.localcodeThis work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.nb_NO

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